- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Chromatography in Natural Products
- Protein purification and stability
- Phase Equilibria and Thermodynamics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Mass Spectrometry Techniques and Applications
- Mesoporous Materials and Catalysis
- Crystallization and Solubility Studies
- Spectroscopy and Chemometric Analyses
- Heat and Mass Transfer in Porous Media
- Advanced Chemical Sensor Technologies
- Diffusion Coefficients in Liquids
- Acoustic Wave Resonator Technologies
- Analytical Methods in Pharmaceuticals
- Spectroscopy and Laser Applications
- Cyclone Separators and Fluid Dynamics
- NMR spectroscopy and applications
- Advanced Sensor Technologies Research
- Advancements in Photolithography Techniques
- Field-Flow Fractionation Techniques
- Structural Health Monitoring Techniques
- Aerosol Filtration and Electrostatic Precipitation
- Gas Dynamics and Kinetic Theory
- Granular flow and fluidized beds
Vrije Universiteit Brussel
2016-2025
Research Institute for Chromatography
2013
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTAdvances in Ultrahigh-Pressure Liquid Chromatography Technology and System DesignJelle De Vos, Ken Broeckhoven, Sebastiaan Eeltink*View Author Information Vrije Universiteit Brussel, Department of Chemical Engineering, Pleinlaan 2, B-1050, Brussels, Belgium*Phone: +32 (0)2 629 3324. Fax: 3248. E-mail: [email protected]Cite this: Anal. Chem. 2016, 88, 1, 262–278Publication Date (Web):November 24, 2015Publication History Published online8 December...
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTAdvances and Innovations in Liquid Chromatography Stationary Phase SupportsK. Broeckhoven*K. BroeckhovenVrije Universiteit Brussel, Department of Chemical Engineering (CHIS), Faculty Engineering, Pleinlaan 2, 1050 Brussels, Belgium*Email: [email protected]More by K. BroeckhovenView Biographyhttp://orcid.org/0000-0003-0524-7830 G. DesmetG. DesmetVrije BelgiumMore DesmetView BiographyCite this: Anal. Chem. 2021, 93, 1, 257–272Publication Date...
It is shown that all C m and s expressions ever established in the literature are intrinsically fully identical can be derived from a simple parallel plug flow model. Analytically solving this model yields m- s-term exactly correspond to obtained via either method of moments (general rate model) or Giddings' nonequilibrium theory. This holds for open-tubular as well packed monolithic columns. From equivalence, set convenient "translation" could established, enabling swift transition between...
We discuss the most important plot types for kinetic performance of liquid chromatography columns and elaborate on how these plots should best be constructed can made dimensionless. Distinction is between that are suited practitioners (column users) versus those theoreticians column manufacturers.
The reintroduction of superficially porous particles has resulted in a leap forward for the separation performance liquid chromatography. underlying reasons higher efficiency columns packed with these are discussed. newly introduced 5 μm is evaluated and compared to 2.7 3.5 fully using typical test compounds (alkylphenones) relevant pharmaceutical compound (impurity amoxicillin). provide superior kinetic both over entire range conditions. particles, however, appears depend strongly on...
The present study speculates on the potential gain we can expect of a further leap in pressure by moving from current 1500 bar to futuristic 3000 as well reviews main impediments be expected when trying realize such systems. focuses so-called "analytical scale" separations, i.e., separations that are currently carried out 2.1 mm columns, this is state-of-the-art ultrahigh-pressure liquid chromatography (UHPLC) instrumentation.