- Remote Sensing in Agriculture
- Remote Sensing and LiDAR Applications
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Pregnancy-related medical research
- Advancements in Transdermal Drug Delivery
- Fire effects on ecosystems
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Species Distribution and Climate Change
- Musculoskeletal pain and rehabilitation
- Nanoplatforms for cancer theranostics
- Advanced Bandit Algorithms Research
- Wound Healing and Treatments
- Phytochemistry and Biological Activities
- Bee Products Chemical Analysis
- interferon and immune responses
- HIV/AIDS drug development and treatment
- Extracellular vesicles in disease
- Geology and Paleoclimatology Research
- FOXO transcription factor regulation
- Medicinal Plant Pharmacodynamics Research
- Cell Adhesion Molecules Research
- Cancer-related Molecular Pathways
University of Chinese Academy of Sciences
2024
Shanghai Institute of Materia Medica
2024
Chinese Academy of Sciences
2024
China University of Geosciences (Beijing)
2023-2024
Henan University of Traditional Chinese Medicine
2024
Chengdu University of Traditional Chinese Medicine
2023
China University of Geosciences
2023
Peking University
2019-2020
Laboratoire de Génétique Médicale
2007
Laboratory of Molecular Genetics
2007
Acute myeloid leukemia (AML) is a genetically heterogeneous malignant disorder of the hematopoietic system, characterized by accumulation DNA-damaged immature precursors. Here, we find that hCINAP involved in repair double-stranded DNA breaks (DSB) and its expression correlates with AML prognosis. Following DSB, recruited to damage sites where it promotes SENP3-dependent deSUMOylation NPM1. This turn results dissociation RAP80 from site CTIP-dependent resection homologous recombination. NPM1...
Deep learning (DL) models for change detection (CD) are affected by the changed/unchanged and hard/easy sample imbalance during training process. Most of loss functions solving problem a static which is difficult to adapt variation data distribution. In this paper, we propose dynamic method termed adaptive focal function (DAFL). Specifically, first statistically count number samples in different batches data, weighting factor constructed dynamically adaptively balance their proportions....
To investigate the effects of Lathyrol on expression androgen receptor (AR) and sphingosine kinase 2 (SPHK2) in renal cell carcinoma (RCC) mice to further explore mechanism by which inhibits invasion incidence epithelial-mesenchymal transition (EMT).
Although the human intestinal microbiome has been shown to harbor antimicrobial drug resistance genes (ARGs), prevalence of such in a healthy population and their impact on extraintestinal infections that occur community are not well established. This study sought identify ARG mobile elements intestines at California University, compared these those previously identified among uropathogenic Escherichia coli isolated from patients with urinary tract infection same community. We Gram-negative...
In cloudy and rainy regions, frequent cloud cover limits clear data obtained using a single optical sensor, posing substantial challenge for detecting deforestation events on sub-annual scale. this study, scale detection algorithm, namely, the LandTrendr (SSLT) change was developed synergies from multiple sources. First, combined time series constructed by combining Landsat Sentinel-2 data. Second, sliding window applied to spatially normalize normalized burn ratioand eliminate effects of...
Forest disturbance detection is important for revealing ecological changes. Long-time series remote sensing analysis methods have emerged as the primary approach detecting large-scale forest disturbances. Many of existing change algorithms focus primarily on identifying high-intensity disturbances, such harvesting and fires, with only a limited capacity to detect both low-intensity This study proposes an online continuous algorithm multi-intensity disturbances harvest, fire, selective...
Abstract Objective: To investigate the effects of Lathyrol on expression androgen receptor (AR) and sphingosine kinase 2 (SPHK2) in renal cell carcinoma (RCC) mice to further explore mechanism by which inhibits invasion incidence epithelial-mesenchymal transition (EMT). Methods: An RCC xenograft mouse model was constructed, were randomly divided into a group, an experiment group negative control group. The intragastrically gavaged with solution (20 mg/kg), 0.9% NaCl (same volume as that used...
In this paper, we develop a unified framework for lower bound methods in statistical estimation and interactive decision making. Classical techniques -- such as Fano's inequality, Le Cam's method, Assouad's lemma have been central to the study of minimax risk estimation, yet they are insufficient analysis that collect data an manner. The recent bounds making via Decision-Estimation Coefficient (DEC) appear be genuinely different from classical methods. We propose view these distinct...
Abstract Although the human intestinal microbiome has been shown to harbor antimicrobial drug-resistance genes (ARG), prevalence of such in a healthy population and their impact on extraintestinal infections that occur community are not well established. This study sought identify ARG mobile elements intestines at California university, compared these those found uropathogenic Escherichia coli isolated from patients with community-acquired urinary tract infection (CA-UTI). We Gram-negative...
Abstract Precipitation carried by the Asian summer monsoon influences livelihoods of millions people, and there has been a great deal work trying to reveal driving mechanisms behind past changes. Compared widely studied East monsoon, behavior South (SASM) in Pliocene is still not well known. Here, we present new high‐resolution geochemical (Rb/Sr Ti) data from lacustrine Yuanmou Basin (Southwest China) spanning early Pleistocene (4.30–2.0 Ma) that permit detailed analysis hydroclimate...