A5102823286- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Family and Patient Care in Intensive Care Units
- Family and Disability Support Research
- Circadian rhythm and melatonin
- Global Health and Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Biosensors and Analytical Detection
- COVID-19 and Mental Health
- Global Health Workforce Issues
- Dietary Effects on Health
- Pneumothorax, Barotrauma, Emphysema
- Global Maternal and Child Health
- Grief, Bereavement, and Mental Health
- Attachment and Relationship Dynamics
- Sleep and related disorders
- Palliative Care and End-of-Life Issues
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 detection and testing
- Spinal Dysraphism and Malformations
- Family Support in Illness
- Diet and metabolism studies
- Assisted Reproductive Technology and Twin Pregnancy
- Nosocomial Infections in ICU
Harvard University
2018-2023
Beth Israel Deaconess Medical Center
2021-2023
University of Massachusetts Amherst
2022
Brigham and Women's Hospital
2018-2021
Circadian (United States)
2021
Harvard Global Health Institute
2021
Loyola University Chicago
2008
University of Chicago
2008
Appropriate meal timing, despite mistimed sleep, maintains internal circadian alignment and prevents glucose intolerance.
SARS-CoV-2 RNA loads can be detected in the excreta of individuals with COVID-19 and have demonstrated positive correlations clinical infection trends. Consequently, wastewater-based epidemiology (WBE) approaches been implemented globally as a public health surveillance tool to monitor community-level prevalence infections. The majority wastewater specimens are gathered either composite samples via automatic samplers (autosamplers) or grab samples. However, autosamplers expensive challenging...
Evidence on heterogeneity in outcomes of surgical quality interventions low-income and middle-income countries is limited. We explored factors driving performance the Safe Surgery 2020 intervention Tanzania's Lake Zone to distil implementation lessons for low-resource settings. identified higher (n=3) lower performers from quantitative data improvement 14 safety teamwork communication indicators at 0 12 months 10 facilities, using a positive deviance framework. From 72 key informant...
The purpose of this article is to review research concerning adolescent development and family functioning among youth with spina bifida myelomeningocele (SBM). Adolescence a developmental period characterized by substantial changes in biological, psychological, social functioning, as well transformation reorganization within the system. A biopsychosocial-contextual model was utilized describe interface between normative experience chronic health condition SBM. Major empirical findings...
Abstract Background Evidence-based strategies for improving surgical quality and patient outcomes in low-resource settings are a priority. Objective To evaluate the impact of multicomponent safe surgery intervention (Safe Surgery 2020) on (1) adherence to safety practices, teamwork communication, documentation files, (2) incidence maternal sepsis, postoperative site infection. Methods We conducted prospective, longitudinal study 10 control facilities Tanzania’s Lake Zone, across 3-month...
Background: Delirium, an acute decline in attention and global cognitive dysfunction, occurs frequently following cardiac surgery has been demonstrated to be significantly associated with dysfunction reduced functional ability. In the DEXACET trial, we a significant reduction postoperative in-hospital delirium intravenous (IV) acetaminophen when compared placebo. this analysis examined whether protective association also extended 12 month outcomes. Methods: This study was prospective,...
Polypharmacy of sedatives (PP) is a potentially modifiable, iatrogenic risk factor for ICU delirium. The extent to which sedative PP influenced development high rates delirium among critically ill COVID-19 patients unknown. We tested the hypothesis that PP, defined as use four or more classes intravenous agents, mediator in causal pathway mechanical ventilation and
Objectives To describe incidence and risk factors of loss previous independent living through nonhome discharge or home with health assistance in survivors intensive care unit (ICU) admission for coronavirus disease 2019 (COVID-19). Design Multicenter observational study including patients admitted to the ICU from January 2020 till June 30, 2021. Hypothesis We hypothesized that there is a high surviving due COVID-19. Setting Data were included 306 hospitals 28 countries participating SCCM...
Background: Prior studies have shown variation in the intensity of end-of-life care intensive units (ICUs) among patients different races. Objective: We sought to identify levels at end life ICU and assess for any association with race ethnicity. Design: An observational, retrospective cohort study. Settings: A tertiary center Boston, MA. Participants: All critically ill admitted medical surgical ICUs between June 2019 December 2020. Exposure: Self-identified Main Outcome Measure: The...
Introduction Postoperative delirium is common among older cardiac surgery patients. Often difficult to predict and address prophylactically, complicates the postoperative course by increasing morbidity mortality as well prolonging both hospital intensive care unit (ICU) lengths of stay. Based on our pilot trial, we intend study effect scheduled 6-hourly acetaminophen administration for 48 hours post-cardiac with cardiopulmonary bypass (CPB) incidence in-hospital long-term neurocognitive...
Recent studies suggest that eating during the biological night/habitual rest phase may increase obesity risk, even when caloric intake and physical activity are controlled for. Preliminary data indicate circadian timing system can influence energy expenditure (EE) after a meal, i.e. diet-induced thermogenesis (DIT), with lower DIT in evening (during night shift simulation protocol). Although unmasking protocols using constant routine (CR) have shown rhythms overall EE, they not thus far...
Kelly, Lauren; Novack, Lena; Banner-Goodspeed, Valerie; Bose, Somnath Author Information