A5046357555- Multiple Sclerosis Research Studies
- Brain Tumor Detection and Classification
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Sleep and related disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Effects of Vibration on Health
- Retinal Development and Disorders
- Peripheral Neuropathies and Disorders
- Olfactory and Sensory Function Studies
- Respiratory viral infections research
- Systemic Lupus Erythematosus Research
- Cancer-related cognitive impairment studies
- SARS-CoV-2 and COVID-19 Research
- Bacterial Infections and Vaccines
- Vitamin D Research Studies
- Balance, Gait, and Falls Prevention
- Vestibular and auditory disorders
- Pneumonia and Respiratory Infections
- Glaucoma and retinal disorders
- Circadian rhythm and melatonin
- Medication Adherence and Compliance
- Psoriasis: Treatment and Pathogenesis
- Genomics and Rare Diseases
- Liver Diseases and Immunity
- Older Adults Driving Studies
Carmel Medical Center
2016-2025
Technion – Israel Institute of Technology
2015-2025
Clalit Health Services
2022-2025
Clinical Research Associates
2024
MicroVision (United States)
2016
Ben-Gurion University of the Negev
2007
Israel Defense Forces Medical Corps
2005
Abstract Background Flu-like symptoms (FLS) are common side effects of interferon beta (IFN-β) treatment in patients with Multiple Sclerosis (PwMS) and associated post-injection cytokine surge. We hypothesized that vitamin D3 supplementation would ameliorate FLS by decreasing related serum cytokines’ levels. Methods In a randomized, double blind study 45 IFNβ-treated PwMS, 21 were assigned to 800 IU per day (low dose), while 24 received 4,370 (high dose) for one year. assessed monthly...
The association between subjective cognitive fatigue and objective dysfunction in patients with multiple sclerosis (PwMS) has been studied, conflicting results.To explore the impact of on function, while controlling for influence depression, disability, comorbidities, psychotropic medications.PwMS completed a computerized testing battery age- education-adjusted domain scores. Disability (Expanded Status Scale (EDSS)), fatigue, depression were concurrently evaluated.In all, 699 PwMS included....
Highlights•One in four pwMS had a discordance between their physiological and perceived fall-risk.•This was not explained by cognitive performance.•Lower performance associated with higher fall-risk pwMS.AbstractBackgroundCognitive impairment is linked increased risk of falls people multiple sclerosis (pwMS), but it clear whether may help to account for the due actual functioning individual's perception fall-risk. This study examined relationship concordance/discordance pwMS.Methods: In this...
Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) limited to an accelerated recovery. We aimed evaluate impact time from symptoms onset IVMP initiation and dose on visual recovery among people with MS‐ON. Methods A retrospective cohort study MS‐ON was undertaken. The associations between as well best‐corrected acuity (BCVA) improvement after 6–12 mo were analyzed. Results Sixty‐one events ON 61...
To assess the relation between stress caused by perils of rocket attack on civilian centers in northern Israel during 2006 war Hezbollah and multiple sclerosis (MS) exacerbations.Participants were 156 patients with relapsing-remitting MS. We compared number relapses after similar time periods at preceding year. Exposure to events resulting subjective evaluated means structured interviews using questionnaires previously validated.During 33 days war, there 18 among our patients, 1 6 over 12...
Switching disease-modifying therapy (DMT) may be considered for relapsing–remitting multiple sclerosis (RRMS) if a patient's current is no longer optimal. This was particularly important during the recent COVID-19 pandemic because of considerations around immune deficiency and impaired vaccine response associated with B cell-depleting DMTs. real-world, single-center study aimed to evaluate change or decline in functional ability overall disease stability people RRMS who were switched from...
The objective of this article is to examine the role coping strategies in multiple sclerosis outcomes among civilians under a military attack during 2006 war between Hezbollah and Israel. Participants were 156 patients with relapsing—remitting sclerosis. We analysed relationships emotional distress exacerbation. also assessed model relationship perceived stress, event-related increased risk exacerbations using multivariate logistic regression. Ways subjective stress evaluated by means...
Systemic inflammation and nutritional deficiencies are characteristics of Crohn's disease (CD) have been suggested to influence cognitive performance. This study assessed function in patients with CD.Participants were adult CD arriving at routine follow-up. Subjective complaints, depression, anxiety, fatigue, sleep evaluated by validated questionnaires. characteristics, blood tests, activity index obtained. Nutritional risk was derived from serum albumin change body weight. Montreal...
Background Patients with Multiple Sclerosis (PwMS) display altered lipoproteins levels and function, which seem to affect disease risk progress. Whether disease-modifying therapies the lipoprotein profile in PwMS has scarcely been studied. Objective The study aims assess whether fingolimod dimethyl fumarate (DMF) PwMS. Methods We compared retrospectively blood of 29 fingolimod-treated 41 DMF-treated patients before after 3 12 months therapy. treated cholesterol-reducing medications were not...
Adherence to multiple sclerosis (MS) disease-modifying drugs (DMDs) is essential for realization of their optimal effectiveness and benefits.To evaluate the usefulness validity a smartphone-based e-diary as tool adherence assessment well its promoter DMDs.An MS tailored (MyMS&Me) reminded patients take DMDs on time. DMD intake was self-recorded in by participants. Three methods evaluation were compared: derived, retrospective self-reported, medication possession rate (MPR). The proportion...