Lei Zhou

ORCID: 0000-0003-0546-8510
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About
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Research Areas
  • Graphene and Nanomaterials Applications
  • Cardiac Imaging and Diagnostics
  • Genetics, Aging, and Longevity in Model Organisms
  • Telomeres, Telomerase, and Senescence
  • dental development and anomalies
  • Natural product bioactivities and synthesis
  • Advanced X-ray and CT Imaging
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Viral Infections and Immunology Research
  • Cardiovascular Health and Disease Prevention
  • melanin and skin pigmentation
  • Intracranial Aneurysms: Treatment and Complications
  • Endodontics and Root Canal Treatments
  • Dental Radiography and Imaging
  • Advanced MRI Techniques and Applications
  • SARS-CoV-2 and COVID-19 Research
  • Traditional Chinese Medicine Analysis
  • COVID-19 Clinical Research Studies

Jinzhou Medical University
2024

Zhejiang Shuren University
2024

Nanjing Medical University
2024

Jiangsu Province Hospital
2024

Central South University
2023

Abstract Diffuse myocardial fibrosis is associated with adverse outcomes in heart failure preserved ejection fraction (HFpEF). Dual-energy CT (DECT) can noninvasively assess by quantification of extracellular volume (ECV) fraction. This study evaluated the association between ECV measured DECT and clinical patients HFpEF. 125 hospitalized HFpEF were enrolled this retrospective cohort study. was using late iodine enhancement. The composite endpoint defined as hospitalization all-cause...

10.1038/s41598-024-58271-9 article EN cc-by Scientific Reports 2024-03-29

Objective Natural product-derived biomaterials are highly desired as possible ingredients in cosmetics, they often safe and effective. Salvianic acid A (SAA) salvianolic B (SAB) the primary water-soluble of Salvia miltiorrhiza Bunge ( Lamiaceae). These compounds have extensive applications both effective biocompatible bioactive agents for treatment various diseases including cardiovascular disorders, liver ailments, neuroprotection. This study aimed to evaluate skin-whitening effects SAA SAB...

10.1177/1934578x231219604 article EN cc-by-nc Natural Product Communications 2024-01-01

Abstract Aims Acute myocarditis (AM) has been recognized as a rare complication of coronavirus disease 2019 (COVID‐19) infection. This study was conducted to present the clinical characteristics, courses and short‐term prognoses Omicron variant severe acute respiratory syndrome 2 (SARS‐CoV‐2) induced AM in China, which unavailable so far. Methods results Data from 28 patients diagnosed with definite COVID‐19–associated 6 hospitals China between 1 December 2022 30 June 2023 were collected...

10.1002/ehf2.15048 article EN cc-by-nc-nd ESC Heart Failure 2024-09-19

Background: Human dermal fibroblasts (HDFs) play a critical role in skin aging and wound healing. However, the underlying mechanism of HDF healing elderly have not been well defined. This study aims to elucidate mechanisms HDFs senescenc how senescent affect aged skin.Methods: The expression levels SPESP1 were evaluated vivo vitro experiments. Additionally, proteomics, RNAseq, immunoprecipitation, liquid chromatography-mass spectrometry (LC-MS) Chromatin immunoprecipitation (ChIP) analysis...

10.2139/ssrn.4634805 preprint EN 2023-01-01
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