Fahad Akhtar

ORCID: 0000-0003-0548-0333
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About
Contact & Profiles
Research Areas
  • Proteoglycans and glycosaminoglycans research
  • Graphene and Nanomaterials Applications
  • Hydrogels: synthesis, properties, applications
  • Nanoparticle-Based Drug Delivery
  • Cell death mechanisms and regulation
  • Phagocytosis and Immune Regulation
  • Biochemical and Structural Characterization
  • vaccines and immunoinformatics approaches
  • HER2/EGFR in Cancer Research
  • Toxin Mechanisms and Immunotoxins
  • Viral Infections and Vectors
  • Food and Agricultural Sciences
  • interferon and immune responses
  • Urinary Tract Infections Management
  • Biochemical Analysis and Sensing Techniques
  • Calcium signaling and nucleotide metabolism
  • RNA Interference and Gene Delivery
  • Antibiotic Use and Resistance
  • Bacterial Identification and Susceptibility Testing
  • Nanoplatforms for cancer theranostics
  • Histone Deacetylase Inhibitors Research
  • Protein Degradation and Inhibitors
  • Dendrimers and Hyperbranched Polymers
  • Antimicrobial Peptides and Activities
  • Cell Adhesion Molecules Research

China Pharmaceutical University
2018-2025

Bristol-Myers Squibb (United States)
2022

University of Chinese Academy of Sciences
2020-2021

Institute of Genetics and Developmental Biology
2020-2021

Chinese Academy of Sciences
2020-2021

Hazara University
2016-2017

The identification of agonists the stimulator interferon genes (STING) pathway has been an area intense research due to their potential enhance innate immune response and tumor immunogenicity in context immuno-oncology therapy. Initial efforts identify STING focused on modification 2',3'-cGAMP (1) (an endogenous activator ligand) other closely related cyclic dinucleotides (CDNs). While these have successfully identified novel CDNs that progressed into clinic, utility is currently limited...

10.1021/acs.jmedchem.1c01986 article EN Journal of Medicinal Chemistry 2022-02-02
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