A5078460819- Nonmelanoma Skin Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer and Skin Lesions
- Ear and Head Tumors
- Reconstructive Facial Surgery Techniques
- Immunotherapy and Immune Responses
- Cutaneous Melanoma Detection and Management
- Melanoma and MAPK Pathways
- Epigenetics and DNA Methylation
- Congenital limb and hand anomalies
- Respiratory and Cough-Related Research
- Ear Surgery and Otitis Media
- Nasolacrimal Duct Obstruction Treatments
- Poisoning and overdose treatments
- Cancer Genomics and Diagnostics
- Carcinogens and Genotoxicity Assessment
- Facial Nerve Paralysis Treatment and Research
- Hedgehog Signaling Pathway Studies
- Reconstructive Surgery and Microvascular Techniques
- Tumors and Oncological Cases
- Intracerebral and Subarachnoid Hemorrhage Research
- Head and Neck Cancer Studies
- Neuroendocrine Tumor Research Advances
- Neurological and metabolic disorders
- Mechanisms of cancer metastasis
RWTH Aachen University
2021-2025
Centre Hospitalier Régional et Universitaire de Nancy
2018
Fachklinik Hornheide
2009-2014
Johannes Gutenberg University Mainz
2007
Background Enhancer of zeste homolog 2 (EZH2) is a transcriptional enzyme implicated in tumor development and often correlated to poor patient outcomes various malignancies. The study evaluated methods for EZH2 expression lip ear squamous cell carcinomas (LSCC, ESCC) by matching patients with without lymph node metastasis (LNM) further analysis clinical outcome parameters. inhibition therapy has shown promising results multiple cancer entities, ongoing research exploring its potential other...
Tumor budding (TB) is a histomorphological characteristic of the tumor invasion front and it has an impact on outcome prediction for head neck squamous cell carcinoma (HNSCC) aetiopathology. The average TB score (TB rel) all tumor-positive marginal sections (n = 443) in primary was analyzed FFPE-fixed slices 66 patients with HNSCC, they were compared cryo-fixed sections. rel correlates aggressiveness (i.e., lymph node metastasis quantity, ratio, extra capsular growth, Pn1, pV1, grading)....
High IMP3 expression is correlated with a worse outcome. Until now, there have been no data about and clinical outcome for high-risk localisation of squamous cell carcinoma the skin (cSCC).One-hundred twenty-two patients cSCC lip ear were included, in tumours was immunohistochemically assessed different evaluation approaches. Subsequently, subgroups analysed matched pair approach pathologic parameters. In following, analysis methods tested suitability.We found significant correlation between...
Among cutaneous squamous cell carcinomas, the ear (ecSCC) is one of most common sites. Loco regional lymph node metastasis found in six to eleven percent cases, corresponding increased compared other The aim this study was test markers PD-L1, PD-1, CD4, CD8, and FoxP3 for suitability as prognostic predictive markers.Sixty-four patients with ecSCC were included study. expression immunohistochemical (PD-L1, FOXP3) correlated retrospective clinic pathological parameters (lymph metastasis,...