A5034984783- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Immune Response and Inflammation
- Neonatal Respiratory Health Research
- Adipokines, Inflammation, and Metabolic Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Liver Disease Diagnosis and Treatment
- COVID-19 Impact on Reproduction
- Immune cells in cancer
- Lipoproteins and Cardiovascular Health
- Inflammasome and immune disorders
- Nitric Oxide and Endothelin Effects
- SARS-CoV-2 detection and testing
- Pancreatitis Pathology and Treatment
- Adipose Tissue and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
Université de Montréal
2022-2024
Hôpital Maisonneuve-Rosemont
2022-2024
Hospital General de México
2020-2022
Universidad Nacional Autónoma de México
2020-2022
There is a deep need for mortality predictors that allow clinicians to quickly triage patients with severe coronavirus disease 2019 (Covid-19) into intensive care units at the time of hospital admission. Thus, we examined efficacy lymphocyte-to-neutrophil ratio (LNR) and neutrophil-to-monocyte (NMR) as in-hospital death admission in Covid-19. A total 54 Mexican adult Covid-19 met hospitalization criteria were retrospectively enrolled, followed-up daily until discharge or death, then assigned...
Aberrant immune responses, including hyperresponsiveness to Toll-like receptor (TLR) ligands, underlie acute respiratory distress syndrome (ARDS). Type I interferons confer antiviral activities and could also regulate the inflammatory response, whereas little is known about their actions resolve aberrant inflammation. Here we report that interferon-β (IFN-β) exerts partially overlapping, but cooperative with aspirin-triggered 15-epi-lipoxin A 4 (15-epi-LXA ) 17-epi-resolvin D1 counter...
Jahir Rodríguez-Morales, Sebastián Guartazaca-Guerrero, Salma A. Rizo-Téllez, Rebeca Viurcos-Sanabria, Eira Valeria Barrón, Aldo F. Hernández-Valencia, Porfirio Nava, Galileo Escobedo, José Damián Carrillo-Ruiz and Lucía Méndez-García. Exp Neurobiol 2022;31:270-6. https://doi.org/10.5607/en21049
Health care workers (HCW) are at high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The incidence SARS-CoV-2 infection in HCW has been examined cross-sectional studies by quantitative polymerase chain reaction (qPCR) tests, which may lead to underestimating exact rates. We thus investigated the a group dedicated disease 2019 (COVID-19) hospital six-month follow-up period. conducted prospective cohort study on 109 participants both sexes working areas high,...
Laboratory parameters display limited accuracy in predicting mortality coronavirus disease 2019 (COVID-19) patients, as with serum albumin. Emerging evidence suggests that cytokine values may enhance the predictive capacity of albumin, especially interleukin (IL)-15. We thus investigated whether use IL-15-to-albumin ratio enables improving prediction at hospital admission a large group COVID-19 patients. In this prospective cross-sectional study, we enrolled and followed up three hundred...
Sebastián Guartazaca-Guerrero, Jahir Rodríguez-Morales, Salma A. Rizo-Téllez, Helena Solleiro-Villavicencio, Aldo F. Hernández-Valencia, José Damián Carrillo-Ruiz, Galileo Escobedo and Lucía Méndez-García. Exp Neurobiol 2021;30:256-61. https://doi.org/10.5607/en21009
The contribution of the cellular immune response to severity coronavirus disease 2019 (COVID-19) is still uncertain because most evidence comes from patients receiving multiple drugs able change function. Herein, we conducted a prospective cohort study and obtained blood samples 128 unvaccinated healthy volunteers examine in vitro pattern CD4+ CD8+ T cells monocyte subsets polyclonal stimuli, including anti-CD3, anti-CD28, poly I:C, severe acute respiratory syndrome type 2 (SARS-CoV-2)...
Objective: Intensive care units (ICUs) collapsed under the global wave of coronavirus disease 2019 (COVID-19).Thus, we designed a clinical decision-making model that can help predict at hospital admission what patients with COVID-19 are higher risk requiring critical care.Methods: This was cross-sectional study in 119 met hospitalization criteria for including less than 30 breaths per minute, peripheral oxygen saturation < 93%, and/or ≥ 50% lung involvement on imaging.Depending need care,...
The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).Mortality attributable to COVID-19 remains considerably high, with case fatality rates as high 8-11%.Early medical intervention in patients who are seriously and critically ill reduces fatal outcomes.Thus, there an urgent need identify biomarkers that could help clinicians determine which SARS-CoV-2 infection at a higher risk of developing most adverse outcomes, include...