A5055637509- Radical Photochemical Reactions
- Electrochemical Analysis and Applications
- NF-κB Signaling Pathways
- Herpesvirus Infections and Treatments
- Electrocatalysts for Energy Conversion
- Sulfur-Based Synthesis Techniques
- Genomics, phytochemicals, and oxidative stress
- Catalytic C–H Functionalization Methods
- interferon and immune responses
- Advanced Chemical Sensor Technologies
- Biosensors and Analytical Detection
- Spectroscopy and Chemometric Analyses
- Genomics and Chromatin Dynamics
- Epigenetics and DNA Methylation
- Catalytic Cross-Coupling Reactions
- Cancer-related gene regulation
- Drug Transport and Resistance Mechanisms
- Chemical Synthesis and Analysis
- Chemical Synthesis and Reactions
- CO2 Reduction Techniques and Catalysts
- Spectroscopy Techniques in Biomedical and Chemical Research
University of Southampton
2023-2025
University of British Columbia
1998-2020
Stony Brook University
1991-1995
State University of New York
1991-1995
Highly encumbered 2,2',6-tri- and 2,2',6,6'-tetra-substituted biaryls are readily prepared from aryl ortho-iodobenzyl ethers through mediated cathodic reduction under flow. The reaction proceeds via the stepwise transfer of two electrons: first to induce loss iodide a radical cyclisation, second polar fragmentation.
The avian reticuloendotheliosis virus T contains within its genome the oncogene rel. expression of this gene is responsible for induction lymphoid tumors in birds. Recently, rel was shown to be related p50 DNA binding subunit transcription factor complex NF-kappa B. Binding sites B are found enhancer regions a number genes, including immunoglobulin kappa and human immunodeficiency long terminal repeat. In communication we identify an activity from T-transformed cells that binds...
The Mitsunobu reaction is a powerful transformation for the one-pot activation and substitution of aliphatic alcohols. Significant efforts have focused on modifying classic conditions to overcome problems associated with purification from phosphine-based byproducts. Herein, we report phosphine free method alcohol that mediated by sulfuryl fluoride. This new effective wide range primary alcohols using phthalimide, di-tert-butyl-iminodicarboxylate, aromatic thiol nucleophiles in 74 % average...
Simulations support time dependent detachment of homogeneous ET and coupled chemistry under mediated electroreduction when E ele < M ArI .
Constitutive and inducible kapp B binding activities associated with v-Rel c-Rel in the cytosol of v-Rel-transformed cells have been identified. These were resolved by electrophoretic mobility shift assay chromatographic techniques into a high-molecular-weight protein-DNA complex designated I containing v- lower-molecular-weight complexes II, III IV which contained only stimulated nucleotides, low pH, detergent. experiments suggest that interaction decreases DNA-binding activity each.