X. Wen

ORCID: 0000-0003-0599-7308
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Research Areas
  • Numerical methods in inverse problems
  • Numerical methods in engineering
  • Bone Tissue Engineering Materials
  • Composite Material Mechanics
  • Differential Equations and Numerical Methods
  • Electromagnetic Scattering and Analysis
  • Additive Manufacturing and 3D Printing Technologies
  • 3D Printing in Biomedical Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Tissue Engineering and Regenerative Medicine
  • Ultrasonics and Acoustic Wave Propagation
  • Nonlinear Dynamics and Pattern Formation
  • Differential Equations and Boundary Problems
  • Advanced Numerical Methods in Computational Mathematics
  • CAR-T cell therapy research
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Advanced Mathematical Modeling in Engineering
  • Ocean Waves and Remote Sensing
  • Thermoelastic and Magnetoelastic Phenomena
  • Liver physiology and pathology
  • Bach Studies and Logistics Development
  • Advanced Research in Science and Engineering
  • Shoulder Injury and Treatment
  • Statistical and Computational Modeling
  • Elite Sociology and Global Capitalism

Henan University of Science and Technology
2024

Institute of Plant Protection
2024

Jiangsu Academy of Agricultural Sciences
2024

University of Shanghai for Science and Technology
2023

Virginia Commonwealth University
2014-2019

Tongji University
2015

Tiandi Science & Technology (China)
2014

Clemson University
2007-2012

University of Leeds
1996-2007

Medical University of South Carolina
2007

Abstract In this paper, several boundary element regularization methods, such as iterative, conjugate gradient, Tikhonov and singular value decomposition for solving the Cauchy problem associated to Helmholtz equation are developed compared. Regularizing stopping criteria convergence, well stability, of numerical methods proposed analysed. The can be regularized by various general presented in but more accurate results obtained classical methods. Copyright © 2004 John Wiley & Sons, Ltd.

10.1002/nme.1031 article EN International Journal for Numerical Methods in Engineering 2004-05-24

This article is concerned with the numerical solution of an inverse source problem associated variable coefficients convection-diffusion equation. The Dual Reciprocity Boundary Element Method (DRBEM) combined iterative Sequential Quadratic Programming (SQP) procedure in order to identify locations and strengths several point sources. As number sources needs be estimated a priori, there are three possible cases, namely correct, over under estimation this number. All situations investigated...

10.1080/17415970600731274 article EN Inverse Problems in Science and Engineering 2007-06-12

10.1016/j.enganabound.2004.06.003 article EN Engineering Analysis with Boundary Elements 2004-08-27

Bone tissue engineering is an emerging field providing viable substitutes for bone regeneration. Freeform fabrication provides effective process tool to manufacture scaffolds with complex shapes and designed properties. We developed a novel precision extruding deposition (PED) technique fabricate composite polycaprolactone∕hydroxyapatite (PCL∕HA) scaffolds. 25% concentration by weight of HA was used reinforce 3D Two groups having 60% 70% porosities pore sizes 450μm 750μm respectively, were...

10.1115/1.2898411 article EN Journal of Manufacturing Science and Engineering 2008-04-01

Purpose To develop a numerical technique for solving the inverse source problem associated with constant coefficients convection‐diffusion equation. Design/methodology/approach The proposed is based on boundary element method (BEM) combined an iterative sequential quadratic programming (SQP) procedure. governing equation transformed into Helmholtz and ill‐conditioned system of equations that arises after application BEM solved using technique. Findings presented in this paper well‐suited...

10.1108/09615530610644235 article EN International Journal of Numerical Methods for Heat &amp Fluid Flow 2006-02-01

The identification of the space-dependent coefficient in two-dimensional Helmholtz-type equations from a complete knowledge field modelled by these and its normal derivative on boundary additional internal measurements is investigated. This problem approached combining regularized dual reciprocity element method (DRBEM) with constrained non-linear minimisation technique. optimal regularization parameter chosen according to Morozov's discrepancy principle. accuracy, convergence stability...

10.1080/17415970600844325 article EN Inverse Problems in Science and Engineering 2006-11-06

The regulation of plant biomass degradation by fungi is critical to the carbon cycle, and applications in bioproducts biocontrol. Trichoderma harzianum an important degrader, enzyme producer, biocontrol agent, but few putative major transcriptional regulators have been deleted this species. T. ortholog activator XYR1/XlnR/XLR-1 was deleted, mutant strains were analyzed through growth profiling, enzymatic activities, transcriptomics on cellulose. From plate cultures, Δxyr1 had reduced...

10.3390/biom14020148 article EN cc-by Biomolecules 2024-01-24

The shoulder is one of the most complex anatomical structures in body, consisting bones, muscles, tendons, bursae, joint capsules, nerves, and blood vessels. Shoulder pain common musculoskeletal syndromes clinically, according to statistics, prevalence adult population 11% 27%, lifetime as high 67%. There are also significant differences across age gender. Typically, stems from trauma, degeneration, inflammation, vascular disease, referred other parts head, neck, hands. Studies have shown...

10.32629/jcmr.v5i3.2768 article EN Journal of Clinical Medicine Research 2024-10-24

Receptor downregulation is instrumental for many therapeutic interventions. knockout through gene-editing technologies efficient but can introduce off-target mutations and chromothripsis. Regulation of gene expression at the protein level a promising alternative. Here, we present results showing targeted T cell antigen receptor (TCR) degradation using chimeric E3 fusion proteins that call Targeting Chimeras (ReceptorTAC). We show TCR dependent on enzymatically active, membrane-anchored...

10.1021/acssynbio.1c00397 article EN ACS Synthetic Biology 2022-05-13
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