Wilfred Mabeche Anjago

ORCID: 0000-0003-0531-7499
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About
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Research Areas
  • Fungal and yeast genetics research
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Fungal Biology and Applications
  • Microbial Natural Products and Biosynthesis
  • Plant Pathogens and Resistance
  • Mycotoxins in Agriculture and Food
  • Plant Disease Resistance and Genetics
  • Plant tissue culture and regeneration
  • Biofuel production and bioconversion
  • Fermentation and Sensory Analysis
  • Banana Cultivation and Research
  • Plant nutrient uptake and metabolism
  • Infectious Diseases and Mycology
  • Mycorrhizal Fungi and Plant Interactions

Fujian Agriculture and Forestry University
2016-2025

Institute of Plant Protection
2023-2024

Jiangsu Academy of Agricultural Sciences
2023-2024

Minjiang University
2022

Protein phosphatases are crucial enzymes that regulate key cellular processes such as the cell cycle, gene transcription, and translation in eukaryotes. Seven PP2C protein have been identified Magnaporthe oryzae. However, their synergistic roles pathology physiology of M. oryzae remain poorly investigated. By qRT-PCR analysis, we found PTC1 PTC2 significantly upregulated PTC5 deletion mutant. The double MoPTC5/MoPTC1 MoPTC5/MoPTC2 genes reduced hyphal growth, conidiophore formation,...

10.3390/jof11030231 article EN cc-by Journal of Fungi 2025-03-18

Rice blast caused by Magnaporthe oryzae pathotype is the worst disease that leads to serious food insecurity globally. Understanding rice pathogenesis therefore essential for development of mitigation strategy. Reverse phosphorylation mediated phosphatases perform a vital function in activation diverse biological mechanisms within eukaryotic. However, little has been reported on roles PP2Cs virulence fungus. In this current work, we deployed functional genomics and biochemical approach...

10.20944/preprints202503.1471.v1 preprint EN 2025-03-20

Oomycetes are devastating soil-borne plant pathogens, and cause numerous losses on diverse crops worldwide. In this study, our aim was to identify actinomycetes with antimicrobial activity towards oomycetes from the rhizosphere of soybean. Strong growth inhibition P. myriotylum found in dual culture a strain called 11 × 1, also using 1 cell-free filtrate EtOAc extract. The growth-inhibiting filtrates stable at high temperatures, acidic alkaline conditions. identified as Streptomyces highest...

10.1080/09583157.2023.2301646 article EN Biocontrol Science and Technology 2024-01-10

Summary Plants generate multitude of aldehydes under abiotic and biotic stress conditions. Ample demonstrations have shown that rice‐derived enhance the resistance rice against rice‐blast fungus Magnaporthe oryzae . However, how fungal pathogen nullifies inhibitory effects host to establish compatible interaction remains unknown. Here we identified evaluated in vivo transcriptional activities M. aldehyde dehydrogenase (ALDH) genes. Transcriptional analysis ALDH genes revealed acetylating...

10.1111/1462-2920.13888 article EN Environmental Microbiology 2017-08-11

Biopesticides are an attractive biotechnological alternative to conventional pesticides for soil-borne plant diseases. A screening strategy with over 100 actinomycetes bacteria isolated from diverse rhizosphere soils uncovered the Streptomyces rochei strain JK1 as a potent inhibitor of oomycete growth. The culture filtrates inhibited growth in plate assays and could suppress two major oomycete-caused diseases caused by Pythium myriotylum Phytophthora sojae. macrolide secondary metabolite...

10.1016/j.biocontrol.2023.105411 article EN cc-by-nc-nd Biological Control 2023-12-06

Fusarium wilt, caused by oxyporum f. sp. cubense (Foc), is the most serious disease affecting banana production. To clarify distribution of Foc races in Fujian Province China, 79 soil samples were collected from four regions Zhangzhou City, primary production area Fujian. We isolated and identified 12 strains based on internal transcribed spacer (ITS) sequence analysis, PCR amplification using Foc-specific primers pathogenicity assays. Our analysis indicated that 11 isolates belong to race...

10.1016/s2095-3119(18)62149-5 article EN other-oa Journal of Integrative Agriculture 2019-08-01

Abstract BACKGROUND Sanguinarine (SAN) is a benzophenanthridine alkaloid that broadly targets range of pathways in mammalian and fungal cells. In this study we set out to explore the molecular mechanism sanguinarine inhibition development pathogenicity Magnaporthe oryzae with hope will bolster antiblast agents. RESULTS We found fungus exhibited significant reduction vegetative growth hyphal melanization while spores produced long germ tubes on artificial hydrophobic surface characteristic...

10.1002/ps.6508 article EN Pest Management Science 2021-06-11

Reversible protein phosphorylation is essential in cellular signal transduction. The rice blast fungus Magnaporthe oryzae contains six putative type 2C phosphatases, namely MoPtc1, MoPtc2, MoPtc5, MoPtc6, MoPtc7, and MoPtc8. major functions of MoPtc1 MoPtc2 have been reported recently. In this communication, we found that were induced by calcium chloride. We also the deletion both resulted overstimulation high-osmolarity glycerol (Hog1) pathogenicity MAP kinase 1 (Pmk1) pathways M. oryzae....

10.3390/jof8121287 article EN cc-by Journal of Fungi 2022-12-08

The regulation of plant biomass degradation by fungi is critical to the carbon cycle, and applications in bioproducts biocontrol. Trichoderma harzianum an important degrader, enzyme producer, biocontrol agent, but few putative major transcriptional regulators have been deleted this species. T. ortholog activator XYR1/XlnR/XLR-1 was deleted, mutant strains were analyzed through growth profiling, enzymatic activities, transcriptomics on cellulose. From plate cultures, Δxyr1 had reduced...

10.3390/biom14020148 article EN cc-by Biomolecules 2024-01-24

Protein kinases and phosphatases catalyze the phosphorylation dephosphorylation of their protein substrates, respectively, these are important mechanisms in cellular signal transduction. The rice blast fungus Magnaporthe oryzae possesses 6 type 2C class, including MoPtc1, 2, 5, 6, 7 8. However, only very little is known about roles filamentous fungi. Here in, we deployed genetics molecular biology techniques to identify, characterize establish MoPtc5 MoPtc7 M. development pathogenicity. We...

10.3390/jof9010001 article EN cc-by Journal of Fungi 2022-12-20

Abstract Reversible protein phosphorylation is essential in cellular signal transduction. The rice blast fungus Magnaporthe oryzae , contains six putative type 2c phosphatases namely; MoPtc1, MoPtc2, MoPtc5, MoPtc6, MoPtc7 and MoPtc8 respectively. In this study, we carried out transcription expression analysis found that MoPtc2 are significantly induced during pathogen-host interactions. Subsequent deletions of MoPtc1 or not only resulted increased sensitivity to cell wall stress mediated by...

10.1101/2022.09.09.507255 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-09-10
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