- Fungal and yeast genetics research
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Mycotoxins in Agriculture and Food
- Cellular transport and secretion
- Plant Disease Resistance and Genetics
- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Plant Reproductive Biology
- Mycorrhizal Fungi and Plant Interactions
- Microbial Natural Products and Biosynthesis
- Plant Molecular Biology Research
- Plant Pathogenic Bacteria Studies
- Retinopathy of Prematurity Studies
- Genomics and Chromatin Dynamics
- Plant Virus Research Studies
- Plant Pathogens and Resistance
- DNA Repair Mechanisms
- Photosynthetic Processes and Mechanisms
- Plant pathogens and resistance mechanisms
- Plant Stress Responses and Tolerance
- Genomics and Phylogenetic Studies
- Neonatal Respiratory Health Research
- Plant Parasitism and Resistance
- Nematode management and characterization studies
Fujian Agriculture and Forestry University
2016-2025
Minjiang University
2017-2025
Chinese PLA General Hospital
2019-2025
AspenTech (United States)
2025
Beihang University
2023-2025
Kunming University of Science and Technology
2025
Air Force Medical University
2025
National Clinical Research Center for Digestive Diseases
2025
Xijing Hospital
2025
First Affiliated Hospital of Kunming Medical University
2025
Ustilaginoidea virens (Cooke) Takah is an ascomycetous fungus that causes rice false smut, a devastating emerging disease worldwide. Here we report 39.4 Mb draft genome sequence of U. encodes 8,426 predicted genes. The has ~25% repetitive sequences have been affected by repeat-induced point mutations. Evolutionarily, close to the entomopathogenic Metarhizium spp., suggesting potential host jumping across kingdoms. possesses reduced gene inventories for polysaccharide degradation, nutrient...
DNA methylation promotes transcription generally represses transcription, but in some instances, it has also been implicated activation. Harris et al. identified a protein complex Arabidopsis that is recruited to chromatin by methylation. This specifically activated the of genes are already mildly transcribed had no effect on transcriptionally silent such as transposable elements. The thereby counteracts repression caused transposon insertion neighboring while leaving transposons silent....
Epigenetics is a biological process that modifies and regulates gene expression, affects neuronal function, contributes to pain. However, the mechanism by which epigenetics facilitates maintains chronic pain poorly understood. We aimed determine whether N6-methyladenosine (m6A) specifically modified methyltransferase 14 (METTL14) alters activity governs sensitizing GluN2A subunit of N-methyl-D-aspartate receptor (NMDAR) in dorsal root ganglion (DRG) neurons model chemotherapy-induced...
The Magnaporthe oryzae avirulence gene AvrPiz-t activates immunity in a gene-for-gene fashion to rice mediated by the blast resistance Piz-t. To dissect molecular mechanism underlying their recognition, we initiated cloning of using map-based strategy. was delimited an approximately 21-kb genomic fragment, which six genes were predicted. Complementation tests each these candidate led final identification AvrPiz-t, encodes 108-amino-acid predicted secreted protein with unknown function and no...
The rice blast fungus Magnaporthe oryzae infects plants with a specialized cell called an appressorium, which uses turgor to drive rigid penetration peg through the leaf cuticle. Here, we show that NADPH oxidases (Nox) are necessary for septin-mediated reorientation of F-actin cytoskeleton facilitate cuticle rupture and plant invasion. We report Nox2–NoxR complex spatially organizes heteroligomeric septin ring at appressorium pore, required assembly toroidal network point emergence....
Maintaining active growth and effective immune responses is often costly for a living organism to survive. Fine-tuning the shared cross-regulators crucial metazoans plants make trade-off between immunity. The Arabidopsis regulatory receptor-like kinase BAK1 complexes with receptor kinases FLS2 in bacterial flagellin-triggered immunity BRI1 brassinosteroid (BR)-mediated growth. BR homeostasis signaling unidirectionally modulate FLS2-mediated at multiple levels. We have shown previously that...
Rice blast disease, caused by Magnaporthe oryzae, threatens global food security. The rice pathosystem is a longstanding model system for understanding plant-microbe interactions. In order to elucidate the coevolution of host and pathogen, provide appropriate methods preventing or controlling researchers have focused on evolution virulence factors resistance genes. Thus far, more than 30 (R) genes 12 avirulence (Avr) been cloned. This review summarizes cloned R genes, Avr M. oryzae...
The order Magnaporthales comprises about 200 species and includes the economically scientifically important rice blast fungus take-all pathogen of cereals, as well saprotrophs endophytes. Recent advances in phylogenetic analyses these fungi resulted taxonomic revisions. In this paper we list 28 currently accepted genera with their type available gene genome resources. polyphyletic Magnaporthe 1972 is proposed for suppression, Pyricularia 1880 Nakataea 1939 are recommended protection generic...
Significance Plant SUVH family H3K9 methyltransferases play a key role in connecting the two epigenetic silencing marks, DNA methylation and H3K9me2. However, regulation of protein activities their precise remains unclear. In this research, we performed comprehensive investigation into structure, biochemistry, vivo targeting characteristics histone methyltransferases. For binding methylated DNA, reveal that proteins possess unique thumb loop-dependent base-flipping mechanism....
We examined the genomes of 100 isolates Magnaporthe oryzae (Pyricularia oryzae), causal agent rice blast disease. grouped current field populations M. into three major globally distributed groups. A genetically diverse group, clade 1, which may represent a group closely related lineages, contains both mating types. Two well-separated clades, clades 2 and 3, appear to have arisen as clonal lineages distinct from clade. Examination genes involved in pathways identified clade-specific...
Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is one of most devastating diseases for rice crops, significantly affecting crop yield and quality. During infection process, M. oryzae secretes effector proteins that help in hijacking host's immune responses to establish infection. However, little known about interaction between protein AvrPik-D host Pikh, how increases disease severity promote In this study, we show interacts with zinc finger-type transcription factor WG7...