- Insect Pest Control Strategies
- Phytochemical compounds biological activities
- Natural Compounds in Disease Treatment
- Allelopathy and phytotoxic interactions
- Insect and Pesticide Research
- Natural product bioactivities and synthesis
- Insect-Plant Interactions and Control
- Fungal Plant Pathogen Control
- Plant-Microbe Interactions and Immunity
- Phytochemistry and Biological Activities
- Biological Activity of Diterpenoids and Biflavonoids
- Plant tissue culture and regeneration
- Plant Pathogens and Fungal Diseases
- Plant-derived Lignans Synthesis and Bioactivity
- Plant Virus Research Studies
- Epigenetics and DNA Methylation
- Insect Resistance and Genetics
- Essential Oils and Antimicrobial Activity
- Cancer-related gene regulation
- Soybean genetics and cultivation
- Plant biochemistry and biosynthesis
- Plant Disease Resistance and Genetics
- Fungal Biology and Applications
- Legume Nitrogen Fixing Symbiosis
- Genomics and Chromatin Dynamics
The University of Texas MD Anderson Cancer Center
2018-2025
Northwest A&F University
2015-2025
Zhejiang University
2002-2025
Northwestern Polytechnical University
2025
Ningbo University
2023-2025
Huazhong Agricultural University
2014-2024
Howard Hughes Medical Institute
2022-2024
Duke University
2022-2024
Jilin Agricultural University
2023-2024
Foshan University
2022-2024
Manganese (Mn) is an essential micronutrient for plants playing important role in many physiological functions. OsNRAMP5 a major transporter responsible Mn and cadmium uptake rice, but whether it involved the root-to-shoot translocation distribution of these metals unknown. In this work, was found to be highly expressed hulls. It also leaves expression level decreased with leaf age. High-magnification observations revealed that enriched vascular bundles roots shoots especially parenchyma...
The Magnaporthe oryzae avirulence gene AvrPiz-t activates immunity in a gene-for-gene fashion to rice mediated by the blast resistance Piz-t. To dissect molecular mechanism underlying their recognition, we initiated cloning of using map-based strategy. was delimited an approximately 21-kb genomic fragment, which six genes were predicted. Complementation tests each these candidate led final identification AvrPiz-t, encodes 108-amino-acid predicted secreted protein with unknown function and no...
The lysozyme of bacteriophage T7 is a bifunctional protein that cuts amide bonds in the bacterial cell wall and binds to inhibits transcription by RNA polymerase. structure mutant has been determined x-ray crystallography refined at 2.2-A resolution. folds into an alpha/beta-sheet prominent cleft. A zinc atom located cleft, bound directly three amino acids and, through water molecule, fourth. Zinc required for amidase activity but not inhibition Alignment ligands with those carboxypeptidase...
From transcription to translation, mRNA is complexed with heterogeneous nuclear ribonucleoproteins (hnRNP proteins) that mediate processing, export from the nucleus, and delivery into cytoplasm. Although mechanism unknown, of mature nucleus a critical regulatory step in gene expression. Analyses hnRNP proteins have shown many these are required for this essential cellular process. In study, we characterize Saccharomyces cerevisiae Nab2 protein, which was first identified as poly(A)...
Contact toxicity of essential oils Litsea pungens Hemsl. and L. cubeba (Lour.) Pers. (Lauraceae) blends their major constituents was assessed against third-instar Trichoplusia ni larvae via topical application. Both showed moderate activity T. with LD50 values 87.1 112.5 μg/larva, respectively. 1,8-Cineole from the oil γ-terpinene accounted for much to larvae. The selected indicated a synergistic effect among putatively active inactive constituents, presence all necessary full natural oils....
The production of secondary metabolites with antibiotic properties is a common characteristic to entomopathogenic bacteria Xenorhabdus spp. These not only have diverse chemical structures but also wide range bioactivities medicinal and agricultural interests such as antibiotic, antimycotic insecticidal, nematicidal antiulcer, antineoplastic antiviral. It has been known that cultivation parameters are critical the produced by microorganisms. Even small changes in culture medium may impact...
The effects of temperature, agitation and aeration on glycoprotein GP-1 production by Streptomyces kanasenisi ZX01 in bench-scale fermentors were systematically investigated. maximum final was achieved at an speed 200 rpm, rate 2.0 vvm temperature 30 °C. By using a dynamic gassing out method, the volumetric oxygen transfer coefficient (kLa) also studied. values logarithmic phase increased with increase (from 14.53 to 32.82 h-1) 13.21 22.43 h-1). In addition, successful scale-up from...
Previous studies have suggested that multiwalled carbon nanotubes (MWCNTs) promote plant growth; however, the mechanism is yet to be fully understood. In this study, effects of MWCNTs (20, 100, and 500 mg/L) on (C) nitrogen (N) metabolism in maize were studied explore molecular action plants. The results showed 100 mg/L increased shoot fresh dry weight, root seedling length while other doses no significant effects. Further chlorophyll content, transpiration rate, stomatal conductance,...
Upon stress, eukaryotes typically reprogram their translatome through GCN2-mediated phosphorylation of the eukaryotic translation initiation factor, eIF2α, to inhibit general while selectively translating essential stress regulators. Unexpectedly, in plants, pattern-triggered immunity (PTI) and response other environmental stresses occur independently GCN2/eIF2α pathway. Here, we show that PTI induces mRNA decapping translation, defense mRNAs with a purine-rich element (“R-motif”) are...
This study aimed to investigate the application potential of Portulaca oleracea extract (POE) in active packaging for preservation chilled meat. First, antioxidant capacity and ingredients POE were systematically studied. The results demonstrated that has excellent contains abundant compounds. Subsequently, antioxidant-active films based on chitosan starch containing different concentrations (CS/POE films) successfully developed. main physicochemical mechanical properties CS/POE...
Cadmium (Cd) pollution is a serious threat to plant growth and human health. Although the mechanisms controlling Cd response have been elucidated in other species, they remain unknown Sorghum (Sorghum bicolor (L.) Moench), an important C4 cereal crop. Here, one-week-old sorghum seedlings were exposed different concentrations (0, 10, 20, 50, 100, 150 μM) of CdCl2 effects these on morphological responses evaluated. stress significantly decreased activities enzymes peroxidase (POD), superoxide...
Hormone-activated nuclear receptors (NR) bind to specific regulatory DNA elements associated with their target genes and recruit coactivator proteins remodel chromatin structure, RNA polymerase, activate transcription. The p160 coactivators (e.g., SRC-1, GRIP1, ACTR) directly activated NR can a variety of secondary coactivators. We have established transient-transfection assay system under which the activity various is highly or completely dependent on synergistic cooperation among three...
Methylation of Lys79 on histone H3 by Dot1p is important for gene silencing. The elongated structure the conserved core yeast contains an N-terminal helical domain and a seven-stranded catalytic that harbors binding site methyl-donor active pocket sided with hydrophobic residues. S-adenosyl-L-homocysteine exhibits extended conformation distinct from folded observed in structures SET lysine methyltransferases. A asparagine (Asn479), located at bottom pocket, suggests mechanism similar to...
The efficiency of enzymatic hydrolysis cellulose can be improved by various pretreatments the substrate. In order to increase saccharification wheat straw, we determined effect different on physical structure, chemical components and straw. Our results showed that combination grinding sodium hydroxide (NaOH) treatment had high straws. optimal pretreatment condition was grind straws into sizes 120 meshes followed with 1.0% NaOH for 1.5 h (121°C/15psi). Under this condition, content straw...
Abstract Background The molecular mechanisms of the development and progression bladder cancer are poorly understood. objective this study was to analyze expression Bmi-1 protein its clinical significance in human cancer. Methods We examined mRNA by RT-PCR Western blot, respectively 14 paired cancers adjacent normal tissues. 137 specimens 30 tissue determined immunohistochemistry. Statistical analyses were applied test relationship between Bmi-1, clinicopathologic features prognosis. Results...
Cyclic AMP (cAMP) signaling plays an important role in regulating multiple cellular responses, such as growth, morphogenesis, and/or pathogenicity of eukaryotic organisms fungi. As a second messenger, cAMP is the activation downstream effector molecules. The balance intracellular levels depends on biosynthesis by adenylyl cyclases (ACs) and hydrolysis phosphodiesterases (PDEases). rice blast fungus Magnaporthe oryzae contains high-affinity (PdeH/Pde2) low-affinity (PdeL/Pde1) PDEases,...