- Plant Disease Resistance and Genetics
- Soybean genetics and cultivation
- Plant-Microbe Interactions and Immunity
- Plant Virus Research Studies
- Microbial infections and disease research
- Molecular Biology Techniques and Applications
- Plant Pathogens and Fungal Diseases
- Fungal and yeast genetics research
- Genomics and Phylogenetic Studies
- Plant Pathogens and Resistance
- Legume Nitrogen Fixing Symbiosis
- Transgenic Plants and Applications
- Cancer-related molecular mechanisms research
- Plant and Fungal Interactions Research
- Animal Nutrition and Physiology
- Ferroptosis and cancer prognosis
- Plant pathogens and resistance mechanisms
- Mycotoxins in Agriculture and Food
- Cellular transport and secretion
- Fungal Biology and Applications
- Antimicrobial Peptides and Activities
- Cancer, Hypoxia, and Metabolism
- Aquaculture Nutrition and Growth
- Immune cells in cancer
- Biochemical and Structural Characterization
First Affiliated Hospital of Bengbu Medical College
2024-2025
Fifth Affiliated Hospital of Sun Yat-sen University
2022-2024
Nanjing Medical University
2024
Sun Yat-sen University
2022-2024
Fujian Agriculture and Forestry University
2018-2023
Army Medical University
2022-2023
Southwest Hospital
2022-2023
Shandong Agricultural University
2016-2022
Xinqiao Hospital
2021-2022
Sichuan Agricultural University
2019-2022
Abstract Chloranthales remain the last major mesangiosperm lineage without a nuclear genome assembly. We therefore assemble high-quality chromosome-level of Chloranthus spicatus to resolve enigmatic evolutionary relationships, as well explore patterns evolution among lineages mesangiosperms (eudicots, monocots, magnoliids, Chloranthales, and Ceratophyllales). find that synteny is highly conserved between genomic regions Amborella , Vitis . identify an ancient single whole-genome duplication...
Simple sequence repeats (SSRs) are tandem of DNA that have been used to develop robust genetic markers. These molecular markers powerful tools for basic and applied studies such as breeding. In the model plants in Nicotiana genus e.g. N. benthamiana, a comprehensive assessment SSR content has become possible now because several genomes sequenced. We conducted genome-wide characterization marker development across seven genomes.Here, we initially characterized 2,483,032 SSRs (repeat units...
Potato late blight is a severe and highly epidemic disease caused by Phytophthora infestans that can affect all parts of the plant. This study mainly screened antagonistic strains for good control potato identified strain SDTB038 as Bacillus velezensis according to its morphological chemical properties 16S rRNA, gyrA, gyrB gene sequences. achieved in greenhouses fields promoted plant growth. Two-year field trials (2018 2019) showed B. be used reduce food losses blight, achieving reductions...
Background & Aims: Liver cancer stem cells (LCSCs) mediate therapeutic resistance and correlate with poor outcomes in patients hepatocellular carcinoma (HCC). Fibroblast growth factor (FGF)-19 is a crucial oncogenic driver gene HCC correlates prognosis. However, whether FGF19 signaling regulates the self-renewal of LCSCs unknown. Methods: were enriched by serum-free suspension. Self-renewal characterized sphere formation assay, clonogenicity sorafenib assay tumorigenic potential assays. Ca2+...
The potential toxicity of carbon quantum dots (CQDs) has received much attention because their increasing biomedical applications.
Recently, a new strain of Cercospora sojina (Race15) has been identified, which caused the breakdown resistance in most soybean cultivars China. Despite this serious yield reduction, little is known about why more virulent than others. Therefore, we sequenced Race15 genome and compared it to Race1 sequence, as its virulence significantly lower. We then re-sequenced 30 isolates C. from different regions identifying differential genes using genome-wide association analysis (GWAS).The 40.12-Mb...
Fusarium wilt, caused by oxyporum f. sp. cubense (Foc), is the most serious disease affecting banana production. To clarify distribution of Foc races in Fujian Province China, 79 soil samples were collected from four regions Zhangzhou City, primary production area Fujian. We isolated and identified 12 strains based on internal transcribed spacer (ITS) sequence analysis, PCR amplification using Foc-specific primers pathogenicity assays. Our analysis indicated that 11 isolates belong to race...
Introduction Calcium sensor calcineurin B-like proteins (CBLs) and their interacting partners, CBL-interacting protein kinases (CIPKs), have emerged as a complex network in response to abiotic biotic stress perception. However, little is known about how CBL-CIPK complexes function potatoes. Methods In this study, we identified the components of one potato signaling complex, StCBL4–StCIPK2, characterized its defense against Rhizoctonia solani causing stem canker potato. Results Expressions...
Gene families contain genes that come from the same ancestor and have similar sequences structures. They perform certain specific functions within among different species. Currently, there is no complete process or platform for rapid analysis of plant gene families. In this study, a comprehensive query families, Plant Family Platform (PlantGF), was constructed. The composed four main parts: Search, Tools, Statistics Auxiliary. A total 2 909 580 family members were identified 138 species in...
Metabolic reprogramming is a novel method for the treatment of malignant tumors. The exploration metabolism procedures between radiosensitive and radioresistant tumors may provide perspectives lung adenocarcinoma (LUAD) patients after radiation therapy. In our study, metabolic immune response changes were found cell line (A549RR) its parent cells (A549) using gene ontology Kyoto Encyclopedia Genes Genomes (KEGG) pathway analysis. Nucleotide/amino acid, lipid, glucose process, including...
Phenylalanine ammonia-lyase (PAL) is the crucial enzyme of phenylpropanoid pathway, which plays an important role in plant disease resistance. To understand function PAL Picea asperata, this study, full-length cDNA sequence gene from species was isolated and named PaPAL. The contains a 2160-bp open reading frame (ORF) encoding 720 amino acids with calculated molecular weight 78.7 kDa theoretical isoelectric point 5.88. deduced PaPAL protein possesses specific signature motif...
Abstract The soybean aphid, Aphis glycines , is an extreme specialist and important invasive pest that relies on olfaction for behaviors such as feeding, mating, foraging. Odorant‐binding proteins (OBPs) play a vital role in by binding to volatile compounds regulating insect sensing of the environment. In this work we used rapid amplification complementary DNA ends technology identify characterize 10 genes encoding A. OBPs (AglyOBPs) belonging 3 subfamilies, including 4 classic OBPs, 5...
Thaumatin-like proteins (TLPs) are involved in the plant defense response against pathogens, and most of them exhibit antifungal activity. However, role TLPs pathogen-induced responses spruce is not fully understood. In this study, four TLP genes encoding thaumatin-like protein, designated as PlTLP1–4, were isolated identified from Picea likiangensis needles. Sequence analysis showed that PlTLP1, PlTLP3, PlTLP4 contained 16 conserved cysteine residues, while PlTLP2 had only 10 residues. qPCR...
Abstract Background Frogeye leaf spot (FLS) is a destructive fungal disease that affects soybean production. The most economical and effective strategy to control FLS the use of resistant cultivars. However, limited number loci in management will be countered by emergence new high-virulence Cercospora sojina races. Therefore, we identified quantitative trait (QTL) resistance novel genes using genome-wide association study (GWAS) on 234 Chinese Results A total 30,890 single nucleotide...
Annona atemoya Hort cv. African Pride (AP) is highly valued due to its high quality and unique flavor, but susceptible water-logging. Prevalence of root diseases in saturated soils one the main problems production, which restricts development AP south China, where flooding frequently occurs rainy seasons. However, some annona species, e.g. A. montana, glabra muricata, are relatively tolerant continuous periodic water-logging conditions, limited commercial value. Yet, potential may exist...
Alpha-lactalbumin (α-LA) is a major whey protein in bovine and other mammalian milk, which regulates synthesis of lactose. Little known about its genetic polymorphism whether can be used as potential marker for dairy ingredients, milk yield traits, properties. To investigate polymorphisms their relationship with lactation traits Chinese Holstein cows, single-strand conformation method (PCR-SSCP) direct sequencing were to mark the α-LA gene SNPs. AA (0.7402) AB (0.2598) genotypes screened out...
The exocyst complex is a multisubunit tethering (MTC) for secretory vesicles at the plasma membrane and contains eight subunits, Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, Exo84. While well defined in eukaryotes from yeast to humans, components filamentous fungi show different localization patterns apical tips of hyphae, which suggests that have evolved divergent strategies regulate endomembrane trafficking.
Lentinan (LNT) is a natural and functional polysaccharide isolated from Lentinus edodes fruiting bodies, which functions in stimulating the plant immune response, improving disease resistance regulating growth. This study explores use of LNT as growth regulator attractant cotton production. After treatment with LNT, content malondialdehyde (MDA) seeds decreased, whereas activities polyphenol oxidase (PPO), superoxide dismutase (SOD) peroxidase (POD) leaves increased significantly. also...