A5101100123- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Potassium and Related Disorders
- Neurological disorders and treatments
- Statistical Methods in Epidemiology
- Global Health Care Issues
- Antiplatelet Therapy and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Hydrogen's biological and therapeutic effects
- Hip and Femur Fractures
- Circular RNAs in diseases
First Affiliated Hospital of Wenzhou Medical University
2020-2025
Tianjin First Center Hospital
2024-2025
Tianjin Medical University
2024-2025
Wenzhou Medical University
2020-2025
First Affiliated Hospital of Zhengzhou University
2019-2023
Chinese Medical Association
2022
Wenzhou University
2021
First Affiliated Hospital of Fujian Medical University
2019-2020
First Affiliated Hospital of Henan University of Science and Technology
2020
Fujian Medical University
2020
Background: Left bundle branch pacing (LBBP) is a novel method and has been observed to have low stable thresholds in prior small short-term studies. The objective of this study was evaluate the feasibility safety LBBP large consecutive diverse group patients with long-term follow-up. Methods: This prospectively enrolled 632 pacemaker attempted from April 2017 July 2019. Pacing parameters, complications, ECG, echocardiographic measurements were assessed at implant during follow-up 1, 6, 12,...
Objective: To evaluate the economics and effectiveness of adding dapagliflozin or empagliflozin to standard treatment for heart failure (HF) patients with reduced ejection fraction (HFrEF) in China. Methods: A Markov model was developed project clinical economic outcomes 66-year-old HFrEF. cost-utility analysis performed based mostly on data from outcome trial chronic a (EMPEROR-Reduced) study prevention adverse (DAPA-HF) trial. The primary were measured via total incremental costs...
Background: Maslinic acid (MA), a pentacyclic triterpenoid compound derived from leaves and fruits of Olea europaea, bears multi-pharmacological properties. Our previous studies found that MA exerted cardioprotective effect by modulating oxidative stress, inflammation, apoptosis during myocardial ischemia-reperfusion injury (MIRI). Nevertheless, data regarding the anti-ferroptosis effects on MI/RI remains unidentified Aim Study: This study aimed to explore ferroptosis induced MI/RI, with...
Hypertensive heart disease (HHD) is a significant public health concern in China. We intend to provide an updated estimate of the burden HHD China between 1990 and 2030. prevalence, mortality, disability-adjusted life years (DALYs) data were obtained from Global Burden Disease (GBD) 2019 databases. Temporal trends analyzed using Joinpoint regression models, projections through 2030 estimated by Bayesian age-period-cohort model. In 2020, 334,695 newly prevalent cases 13,196 deaths due...
Background Frailty is increasingly recognized as a critical factor in the risk of chronic kidney disease (CKD), and it also condition that can undergo transitions. However, relationship between frailty transitions CKD aging populations remains underexplored. This study aims to investigate association middle-aged older adults using data from China Health Retirement Longitudinal Study.
To analyze the association between hemoglobin glycation index (HGI) and long-term prognosis of patients with coronary artery disease (CAD) after percutaneous intervention (PCI).Predicted glycated (HbA1c) level was calculated using an established formula HGI represented difference laboratory measured HbA1c predicted HbA1c. A total 1780 were stratified into three subgroups (HGI < -0.4, -0.4 ≦ 0.12 ≧ 0.12). The primary endpoints included all-cause mortality (ACM) cardiac (CM). secondary major...
His-Purkinje conduction system pacing (HPCSP) utilizing His (HBP) or left bundle branch (LBBP) in patients with atrial fibrillation (AF) and wide QRS duration has not been well studied. We assessed the benefit of block (LBBB) correction during HPCSP AF undergoing atrioventricular junction (AVJ) ablation LBBB, compared those narrow duration. This is an observational study consecutive typical LBBB whom we attempted after AVJ for refractory a ventricular ejection fraction (LVEF) ≤ 50%....
Monocyte to lymphocyte ratio (MLR) has been confirmed as a novel marker of poor prognosis in patients with coronary heart disease (CAD). However, the value MLR for CAD after percutaneous intervention (PCI) needs further studies. In present study, we aimed investigate correlation between and long-term PCI. A total 3,461 PCI at First Affiliated Hospital Zhengzhou University were included analysis. According cutoff MLR, all divided into 2 groups: low-MLR group (<0.34, n = 2338) high-MLR...
Background: Left bundle branch pacing (LBBP) is a novel physiological and previous studies have confirmed the feasibility safety of it. The incidence complications in LBBP relatively low as reported. Here we present case interventricular septal hematoma complicating lead implantation. Case summary: was achieved for treatment high-grade atrioventricular block 67-year-old female. Chest pain began 1 h after implantation when electrocardiogram showed ST-T changes. Then bedside echocardiography...
Septal myectomy for obstructive hypertrophic cardiomyopathy (HCM) is associated with conduction block; however, the electrophysiological characteristics of block have not been well characterized. The aim study was to assess feasibility and safety His bundle pacing (HBP) left branch area (LBBAP) in patients septal myectomy-associated block.Patients HCM indications or cardiac resynchronization therapy after were included. Electrophysiological mapping performed identify site block. success...
Background Stress hyperglycemia ratio (SHR) has shown a predominant correlation with transient adverse events in critically ill patients. However, there remains gap comprehensive research regarding the association between SHR and mortality among patients experiencing cardiac arrest admitted to intensive care unit (ICU). Methods A total of 535 their initial ICU admission suffered arrest, according American Medical Information Mart for Intensive Care (MIMIC)-IV database. Patients were...
Abstract Background Previous studies indicated that metabolic heterogeneity of obesity would affect the risk cardiovascular disease (CVD). However, alterations in CVD associated with transitions between various health statuses influenced by status remain unclear. Methods We utilized data from China Health and Retirement Longitudinal Study (CHARLS), a longitudinal cohort study involving Chinese residents aged 45 years older. Baseline were collected 2011–2012, follow‐up surveys conducted up to...
Abstract Background It has been confirmed that the triglyceride to high-density lipoprotein cholesterol ratio (THR) is associated with insulin resistance and metabolic syndrome. However, best of our knowledge, only a few studies small sample sizes have investigated relationship between THR coronary artery disease (CAD). Therefore, we aimed assess correlation long-term mortality in patients CAD after undergoing percutaneous intervention (PCI) study enrolled large number patients. Methods A...
In the present study, we aimed to establish a novel score predict long-term mortality of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients who underwent percutaneous intervention (PCI). A total 2,174 NSTE-ACS from CORFCHD-ZZ study were enrolled as derivation cohort. The validation cohort including 1,808 CORFCHD-PCI study. Receiver operating characteristic analysis and area under curve (AUC) evaluation used select candidate variables. model performance was validated...
Background The Prognostic Nutritional Index (PNI) has been reported to be correlated with long-term outcomes after gastrointestinal tumor surgery. However, our knowledge, only a few studies have shown that the PNI is related cardiovascular diseases. Therefore, we aimed assess association between and in patients coronary artery disease (CAD) undergoing percutaneous intervention (PCI). Methods This was retrospective observational study. A total of 3561 CAD PCI were retrospectively enrolled...
Red blood cell distribution width (RDW) to platelet ratio (RPR) is a novel inflammatory indicator. It integrates the risk prediction of RDW and platelet, which associated with adverse outcomes. However, predictive power RPR in mortality for patients acute myocardial infarction (AMI) remains uncertain. Thus, we aimed explore association between 180-day in-hospital AMI.Data on AMI were extracted from Medical Information Mart Intensive Care IV (MIMIC-IV) database. Patients divided into two...
Abstract We performed left bundle pacing combined with atrioventricular nodal (AVN) ablation in a patient persistent atrial fibrillation and refractory symptomatic heart failure. The major findings were new‐onset intrinsic paced QRS morphology of right branch block (RBBB) pattern after AVN which was at more site compared the RBBB could not be corrected regardless output. Longitudinal dissociation cannot explain this observation, while anatomical separation could. also confirm proximal rather...
The role of activation the coagulation and fibrinolysis system in pathogenesis prognosis cardiovascular diseases (CVDs) has drawn wide attention. Recently, D-dimer to fibrinogen ratio (DFR) is considered as a useful biomarker for diagnosis ischemic stroke pulmonary embolism. However, few studies have explored relationship between DFR disease. In our study, patients were divided into 2 groups according value: lower group (DFR < 0.52, n = 2123) higher ≥ 1073). primary outcome was all-cause...
C-reactive protein (CRP) has been proposed as a contributor to the pathogenesis of coronary artery disease (CAD) and inflammatory reactions, which are associated with decrease in serum albumin, it reported that CRP-to-serum albumin ratio (CAR) can predict CAD severity inpatient ischemic cardiomyopathy (ICM) patients. However, relationship between CAR long-term adverse outcomes patients after percutaneous intervention (PCI) is still unknown.A total 3561 enrolled Outcomes Risk Factors Patients...