A5080305203- Adipose Tissue and Metabolism
- Meat and Animal Product Quality
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- Animal Nutrition and Physiology
- Plant Stress Responses and Tolerance
- Gout, Hyperuricemia, Uric Acid
- Inflammasome and immune disorders
- Diet and metabolism studies
- Lipid metabolism and biosynthesis
- Microbial Metabolites in Food Biotechnology
- Cancer, Hypoxia, and Metabolism
- Muscle metabolism and nutrition
- Biochemical effects in animals
- Nanoparticles: synthesis and applications
- Peroxisome Proliferator-Activated Receptors
- Digestive system and related health
- Veterinary Medicine and Surgery
- Circadian rhythm and melatonin
- biodegradable polymer synthesis and properties
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Cardiac Fibrosis and Remodeling
- Probiotics and Fermented Foods
- Plant Gene Expression Analysis
Hangzhou Academy of Agricultural Sciences
2020-2024
Zhejiang University
2020-2024
Wenzhou Medical University
2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024
Institute of Animal Sciences
2023
Ministry of Education of the People's Republic of China
2022-2023
South China University of Technology
2019-2023
Ministry of Agriculture and Rural Affairs
2023
Affiliated Hospital of North Sichuan Medical College
2021
Guangdong Academy of Medical Sciences
2019-2020
Pork is the most consumed meat in world, and its quality associated with human health. Intramuscular fat (IMF) deposition (also called marbling) a key factor positively correlated various traits lipo-nutritional values of meat. However, cell dynamics transcriptional programs underlying lipid highly marbled are still unclear. Here, we used Laiwu pigs high (HLW) or low (LLW) IMF contents to explore cellular mechanisms highly-marbled pork by single-nucleus RNA sequencing (snRNA-seq) bulk...
CLA improves the lipo-nutritional quality in muscle and these changes are associated with production functions of differential bacteria SCFAs gut Heigai pigs.
Abstract Background In addition to its contractile properties and role in movement, skeletal muscle plays an important function regulating whole-body glucose lipid metabolism. A central component of such regulation is mitochondria, whose quality are essential maintaining proper metabolic homeostasis, with defects processes as autophagy mitophagy involved mitochondria control impairing mass function, potentially leading a number associated diseases. Cold exposure has been reported markedly...
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses is implicated in several auto-inflammatory disorders. Here, we measured miR-223 expression acute intercritical gout patients, after which used RAW264.7 macrophages transfected with a mimic/inhibitor to determine the function monosodium urate (MSU)-induced gouty inflammation. Methods Results: MiR-223 was detected among 122 patients (AG), 118 (IG), 125 healthy subjects (HC). were cultured...
Nanotechnology is one of the most recent approaches employed to defend plants against both biotic and abiotic stress including heavy metals such as Cadmium (Cd). In this study, we evaluated effects titanium dioxide (TiO2) nanoparticles (TiO2 NPs) in alleviating Cd Tetrastigma hemsleyanum Diels et Gilg. Compared with treatment, TiO2 NPs decreased leaf concentration, restored exposure-related reduction biomass about 69% control activities antioxidative enzymes. Integrative analysis...
To gain better insight into the regulatory networks of anthocyanin biosynthesis, an integrated analysis metabolome and transcriptome in purple green leaves Tetrastigma hemsleyanum was conducted. Transcript metabolite profiles were archived by RNA-sequencing data LC-ESI-MS/MS, respectively. There 209 metabolites 4211 transcripts that differentially expressed between leaves. Correlation tests contents transcriptional changes showed 141 significant correlations (Pearson correlation coefficient...
Conjugated linoleic acids (CLAs) have served as a nutritional strategy to reduce fat deposition in adipose tissues of pigs. However, the effects CLAs on lipid profiles serum and how these molecules regulate are still unclear. In this study, we explored regulating terms microbiota based Heigai pig model. A total 56 finishing pigs (body weight: 85.58 ± 10.39 kg) were randomly divided into two treatments fed diets containing 1% soyabean oil or for 40 d. reduced affected fatty composition via...
Abstract Melatonin has been reported to play crucial roles in regulating meat quality, improving reproductive properties, and maintaining intestinal health animal production, but whether it regulates skeletal muscle development weaned piglet is rarely studied. This study was conducted investigate the effects of melatonin on growth performance, development, lipid metabolism animals by intragastric administration solution. Twelve 28-d-old DLY (Duroc × Landrace Yorkshire) piglets with similar...
Cat obesity has become a serious problem that affects cats' lives and welfare. Knowing how to control in pet cats its mechanism is urgently needed. Here, by feeding 30 different diets for 28 d, we explored the effects of 5 cat foods with potato, sweet cassava, rice, wheat as main carbohydrate sources on glycolipid metabolism cats. The results showed dietary did not affect normal growth performance stool scores Notably, found starch gelatinization degree potato cassava food were higher than...
Small fructans improve plant tolerance for cold stress. However, the underlying molecular mechanisms are poorly understood. Here, we have demonstrated that small fructan tetrasaccharide nystose improves stress of primary rice roots. Roots developed from seeds soaked in showed lower browning rate, higher root activity, and faster growth compared to water under chilling Comparative proteomics analysis nystose-treated control roots identified a total 497 differentially expressed proteins. GO...
Studies have demonstrated that cholesterol variability is an independent predictor of cerebrovascular and cardiovascular events.This study aimed to investigate the association visit-to-visit in total (TC) with kidney decline a Chinese community-based population.We assessed intraindividual TC among 6,465 hypertensive participants correlated results endpoints. was measured using standard deviation (SD), average successive (ASV), coefficient variation (CV), mean (VIM). The endpoint this...
Abstract Background Increased left atrium diameter (LAD) is associated with an elevated risk of cardiovascular diseases. The relationship between nutrition status and atrial enlargement (LAE) still unclear. present study aimed to investigate the association famine exposure in early life LAE adulthood. Methods Participants were divided into non‐exposed, fetal, early, middle late childhood exposed groups according birth data. was defined when LAD ≥3.9 cm women ≥4.1 men, or ≥2.3 m −2 by a...
Abstract Background: Polyunsaturated fatty acids (PUFAs) supplementation has been widely discussed as a strategy for improving meat quality in pig production but the effects are inconsistent. This meta-analysis was performed to comprehensively evaluate its on including intramuscular fat (IMF) content, drip loss, color, pH 45min and 24h of pigs. Methods: We searched PubMed Web Science databases (articles published from Jan 1 st , 2000, Oct 16 th 2020) compared PUFAs-supplemented diets with...
Abstract Background Hypertrophic cardiomyopathy (HCM) is characterized by massive myocardial hypertrophy, which the most frequent cause of sudden death and can lead to heart failure (HF) or stroke. The objective this study was explore communication network among various cells in pathological HCM derived from transverse aortic constriction (TAC) mouse model, investigate potential mechanism through data mining, biological informatics analysis, experimental validation. Methods Results...