A5058595486- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Nausea and vomiting management
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder Injury and Treatment
- Quantum Dots Synthesis And Properties
- Nerve Injury and Rehabilitation
- Pain Management and Opioid Use
- Orthopaedic implants and arthroplasty
- Chalcogenide Semiconductor Thin Films
- Pain Mechanisms and Treatments
- Advanced biosensing and bioanalysis techniques
- Pain Management and Treatment
- Peripheral Nerve Disorders
- Total Knee Arthroplasty Outcomes
- Musculoskeletal pain and rehabilitation
- Trauma Management and Diagnosis
- Public Health and Environmental Issues
- Spinal Hematomas and Complications
- Ethics and bioethics in healthcare
- Advanced Photocatalysis Techniques
- Intraoperative Neuromonitoring and Anesthetic Effects
- Nanocluster Synthesis and Applications
- Veterinary Pharmacology and Anesthesia
Hospital Clínico de la Universidad de Chile
2017-2024
University of Chile
2013-2023
McGill University
2019-2020
Association of Perioperative Registered Nurses
2019
Maharaj Nakorn Chiang Mai Hospital
2019
Chiang Mai University
2019
Background This randomized trial compared ultrasound-guided pericapsular nerve group block and suprainguinal fascia iliaca in patients undergoing primary total hip arthroplasty. We selected the postoperative incidence of quadriceps motor (defined as paresis or paralysis knee extension) at 6 hours outcome. hypothesized that, with block, would decrease its occurrence from 70% to 20%. Methods Forty arthroplasty under spinal anesthesia were randomly allocated receive a (n=20) using 20 mL...
Background This randomized trial compared pericapsular nerve group block and periarticular local anesthetic infiltration in patients undergoing primary total hip arthroplasty. We hypothesized that, with block, would decrease the postoperative incidence of quadriceps weakness at 3 hours fivefold (ie, from 45% to 9%). Methods Sixty arthroplasty under spinal anesthesia were randomly allocated receive a (n=30) using 20 mL adrenalized bupivacaine 0.50%, or 60 0.25%. Both groups also received 30...
Fluorescent nanoparticles or quantum dots (QDs) have been intensely studied for basic and applied research due to their unique size-dependent properties. There is an increasing interest in developing ecofriendly methods synthesize these since they improve biocompatibility avoid the generation of toxic byproducts. The use biological systems, particularly prokaryotes, has emerged as a promising alternative. Recent studies indicate that QDs biosynthesis related factors such cellular redox...
Background This randomized trial compared ultrasound-guided interscalene block (ISB) and costoclavicular brachial plexus (CCB) for arthroscopic shoulder surgery. We hypothesized that CCB would provide equivalent analgesia to ISB 30 min after surgery without the risk of hemidiaphragmatic paralysis. Methods All 44 patients received an intermediate cervical plexus. Subsequently, they were or CCB. The local anesthetic agent (20 mL levobupivacaine 0.5% epinephrine 5 µg/mL) pharmacological adjunct...
Although interscalene brachial plexus block (ISB) remains the gold standard for analgesia after shoulder surgery, inherent risks of ipsilateral phrenic nerve and hemidiaphragmatic paralysis (HDP) limit its use in patients with preexisting pulmonary compromise. In a previous Daring Discourse (2017), our research team has identified potential diaphragm-sparing alternatives to ISB undergoing surgery. recent years, field been fertile research, publication multiple randomized controlled trials...
This randomized trial compared ultrasound (US)-guided interscalene block (ISB) and small-volume supraclavicular (SCB) for arthroscopic shoulder surgery. We hypothesized that SCB would provide equivalent analgesia to ISB 30 minutes after surgery without the risk of hemidiaphragmatic paralysis (HDP).All patients received an US-guided intermediate cervical plexus block. In group, was performed with 20 mL levobupivacaine 0.5% epinephrine 5 μg/mL. carried out using same local anesthetic agent: 3...
The habenular complex (HbCpx) is a phylogenetically conserved brain structure located in the epithalamus of vertebrates. Despite its fundamental role decision-making processes and proposed link between dysfunction neuropsychiatric conditions, little known about structural functional organization HbCpx humans. goal this study was thus to provide first systematic morphologic immunohistochemical analysis human begin dissecting nuclear subnuclear organization. Our results confirmed that...
Background The costoclavicular approach targets the brachial plexus in proximal infraclavicular fossa, where lateral, medial, and posterior cords are tightly bundled together. This randomized trial compared single- double-injection ultrasound-guided blocks. We selected onset time as primary outcome hypothesized that, with its single-injection counterpart, technique would result a swifter onset. Methods Ninety patients undergoing upper limb surgery (at or below elbow joint) were randomly...
CuInS2 (CIS) nanoparticles have unique chemical, toxicological and optoelectronic properties that favor their technological applications. In the present work we report a novel one step biomimetic method for aqueous synthesis of CIS nanoparticles, is also low cost environmentally friendly. This uses only CuSO4 InCl3 as precursor salts, biological molecule glutathione sulfur donor stabilizer (NPs). The reaction performed at temperatures, under aerobic conditions atmospheric pressure. produced...
Background This randomized trial compared perineural dexamethasone with combined dexamethasone-dexmedetomidine for ultrasound-guided infraclavicular block. We hypothesized that the combination of adjuvants would result in a longer motor Methods Fifty patients undergoing upper limb surgery block (using 35 mL lidocaine 1%-bupivacaine 0.25% epinephrine 5 µg/mL) were randomly allocated to receive (2 mg) or mg)-dexmedetomidine (50 µg). After performance block, blinded observer assessed success...
Background and objectives This multicenter, randomized trial compared 2, 5, 8 mg of perineural dexamethasone for ultrasound-guided infraclavicular brachial plexus block. Our research hypothesis was that all three doses would result in equivalent durations motor block (equivalence margin=3.0 hours). Methods Three hundred sixty patients undergoing upper limb surgery with were randomly allocated to receive or preservative-free dexamethasone. The local anesthetic agent (35 mL lidocaine...
Background This randomized trial compared perineural dexamethasone (5 mg) and dexmedetomidine (100 µg) for ultrasound-guided infraclavicular brachial plexus block. We hypothesized that both adjuvants would result in similar durations of motor block therefore designed the study as an equivalence (equivalence margin=3.0 hours). Methods One hundred twenty patients undergoing upper limb surgery with (using 35 mL lidocaine 1%–bupivacaine 0.25% epinephrine 5 µg/mL) were randomly allocated to...
CdTe quantum dots (QDs) capped with two relevant biological thiols, glutathione (GSH) or cysteine (Cys) were synthesized in aqueous solution using CdCl2, K2TeO3 and NaBH4 their chemical, spectroscopic biocompatibility properties assessed. Synthesized nanoparticles (NPs) are 3–6 nm diameter, emission spectra between 480–580 depending on QDs size, yields 0.35–0.65. The toxicity of thiol-capped NPs to different bacterial strains was determined. Increased for Cys-capped observed. In addition,...
Background This double-blind, randomized trial compared dural puncture epidural analgesia (DPEA) for labor using 25-gauge and 27-gauge pencil point spinal needles. We hypothesized that both needle sizes would result in similar onset time (equivalence margin=2.5 min) therefore designed the study as an equivalence trial. Methods One hundred forty patients undergoing were to DPEA with (n=70) or After placement of catheter, a bolus 20 mL bupivacaine 0.125% fentanyl 2 µg/mL was administered all...
To the Editor Aside from notable exceptions,[1][1] most randomized trials have investigated diaphragm-sparing nerve blocks for shoulder surgery in setting of postoperative analgesia and not surgical anesthesia.[2][2] However, care patients with pulmonary compromise undergoing
This randomized trial[1][1] compared pericapsular nerve group block and periarticular local anesthetic infiltration in patients undergoing primary total hip arthroplasty. We hypothesized that, with block, would decrease