A5041067860- RNA Interference and Gene Delivery
- Genetic Neurodegenerative Diseases
- Parkinson's Disease Mechanisms and Treatments
- Advanced biosensing and bioanalysis techniques
- Muscle Physiology and Disorders
- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Immunotherapy and Immune Responses
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Advanced Electron Microscopy Techniques and Applications
- Nanoplatforms for cancer theranostics
- Neurological disorders and treatments
- MicroRNA in disease regulation
- Biosensors and Analytical Detection
- Inflammatory Bowel Disease
- Graphene and Nanomaterials Applications
- CRISPR and Genetic Engineering
- Vitamin C and Antioxidants Research
- Anesthesia and Neurotoxicity Research
- Extracellular vesicles in disease
Automation and Process Engineering Laboratory
2022-2024
Université Claude Bernard Lyon 1
2021-2024
Centre National de la Recherche Scientifique
2021-2024
École d'Ingénieurs en Chimie et Sciences du Numérique
2023
University of Verona
2019-2022
mRNA based infectious disease vaccines have opened the venue for development of novel nucleic acids-based therapeutics. For all therapeutics dedicated delivery systems are required, where different functionalities and targeting abilities need to be optimized respective applications. One option advanced formulations with tailored properties lipid-polymer hybrid nanoparticles complex nanostructure, which allow combine features several already well described acid systems. Here, we explored...
The main step in the assessment of nanomaterial safety and suitability for biomedical use is location dynamic tracking nanoparticles (NPs) inside cells or tissues. To precisely investigate uptake mechanisms intracellular fate NPs, transmission electron microscopy technique choice; however, detection NPs may sometimes be problematic. In fact, while containing strongly dense (e.g., metal) components do not require specific methods at ultrastructural level, organic are hardly detectable...
Graphical abstract Abstract Reactive oxygen species (ROS) are important signaling molecules that play key roles in the progression of inflammatory disorders. Owing to a mismatch antioxidant level balance overproduction ROS, induced chronic inflammation can lead several type diseases such as cancer, bowel disease, atherosclerosis, diabetes or neurodegenerative Over last years, nanomedicine has shown tremendous promise ROS-regulating approaches. The development advanced redox-active...