A5076701506- Glioma Diagnosis and Treatment
- 14-3-3 protein interactions
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Plant Disease Resistance and Genetics
- Peptidase Inhibition and Analysis
- Cancer-related gene regulation
- Radiopharmaceutical Chemistry and Applications
- Lanthanide and Transition Metal Complexes
- Advanced Radiotherapy Techniques
- Ubiquitin and proteasome pathways
- Iron oxide chemistry and applications
- Advanced MRI Techniques and Applications
- Lung Cancer Treatments and Mutations
- Memory and Neural Mechanisms
- Nanoparticle-Based Drug Delivery
Midwestern University
2025
University of California, Los Angeles
2020-2024
Astronomy and Space
2022
St. Antonius Ziekenhuis
2011
Amsterdam UMC Location Vrije Universiteit Amsterdam
2010
Background/Objectives: Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancer accounts for over 50,000 new cases annually in United States. The survival rates are markedly different localized OSCC versus metastatic disease, which five-year rate only 39%. Depending on its pathology stage at diagnosis, treatment may involve surgery, radiation, targeted therapy, or conventional chemotherapy. However, there an unmet need reliable biomarkers to predict response link...
Tumor resistance to docetaxel may be associated with reduced drug concentrations in tumor tissue. Positron emission tomography (PET) allows for quantification of radiolabeled ([(11)C]docetaxel) kinetics and might useful predicting response therapy. The primary objective was evaluate the feasibility quantitative [(11)C]docetaxel PET scans lung cancer patients. secondary investigate whether were perfusion, size, dexamethasone administration.Thirty-four patients underwent dynamic PET-computed...
Abstract Patients with degenerative cervical myelopathy (DCM) experience structural and functional brain reorganization. However, few studies have investigated the influence of sex on cerebral alterations. The present study investigates role connectivity (FC) global network topology in DCM healthy controls (HCs). resting-state MRI data was acquired for 100 patients (58 males vs. 42 females). ROI-to-ROI FC topological features were characterized each patient HC. Group differences examined....
Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancers that predominantly affects men accounts for over 50,000 new cancer cases annually in United States. Survival rates are markedly different localized OSCC versus metastatic disease, which five-year survival only 39%. Depending on pathology stage at diagnosis, treatment may involve surgery, radiation, targeted therapy, or conventional chemotherapy. However, there an unmet need reliable biomarkers to predict...
Abstract Background Evidence from single and multicenter phase II trials have suggested diffusion MRI is a predictive imaging biomarker for survival benefit in recurrent glioblastoma (rGBM) treated with anti-VEGF therapy. The current study confirms these findings large, randomized III clinical trial. Methods Patients rGBM were enrolled (1:1), controlled trial (NCT02511405) to compare the efficacy safety of bevacizumab (BV) versus BV combination ofranergene obadenovec (BV+VB-111), an...
Abstract Visual perception plays a critical role in navigating space and extracting useful semantic information crucial to survival. To identify distant landmarks, we constantly shift gaze vectors through saccades, while still maintaining the visual of stable allocentric space. How can sustain so effortlessly? solve this question, have developed new concept NHT (Neural Holography Tomography). This model states that retinotopy is invisible (not available consciousness) must be converted time...
Abstract BACKGROUND Evidence from independent single center as well multicenter phase II trials have suggested diffusion MRI is a strong predictive imaging biomarker for survival benefit in recurrent glioblastoma (rGBM) treated with anti-VEGF monotherapy, but not systemic chemotherapies or combination therapies agents. The current study builds on this body of evidence by evaluating these MR phenotypes large randomized III clinical trial. METHODS Patients rGBM were enrolled (1:1), controlled...