A5088752557- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Chromosomal and Genetic Variations
- Fern and Epiphyte Biology
- Insect and Pesticide Research
- Legume Nitrogen Fixing Symbiosis
- Genetic and Environmental Crop Studies
- Allelopathy and phytotoxic interactions
- GABA and Rice Research
- Plant Stress Responses and Tolerance
- Chromatography in Natural Products
- Insect Pest Control Strategies
- Plasma Applications and Diagnostics
- Diptera species taxonomy and behavior
- Bioactive natural compounds
- Natural product bioactivities and synthesis
- Sesquiterpenes and Asteraceae Studies
- Salivary Gland Disorders and Functions
- Study of Mite Species
- X-ray Diffraction in Crystallography
- Plant Genetic and Mutation Studies
- Plant biochemistry and biosynthesis
University of Belgrade
2014-2024
The Ohio State University
2018
Institute for Medical Research
2000
Institute for Medical Research and Occupational Health
2000
Institute for Medical Research
1998
University of Bonn
1970-1974
Maize Research Institute Zemun Polje
1970
Medicinal plants and their extracts contain substantial quantities of polyphenols. As metabolically active plant metabolites, polyphenols are food components with a wide range biological activities. Given poor absorbability in the digestive tract activity toward human host is typically mediated through interaction intestinal microbes. result, comprise novel group prebiotics. In this study, we tested effect five polyphenol-rich from four medicinal herbs on growth probiotic pathogenic The...
Crop protection still mostly relies on synthetic pesticides for crop pest control. However, the rationale their continued use is shaded by revealed adverse effects, such as relatively long environmental persistence that leads to water and soil contamination retention of residues in food brings high risks human animal health. As part integrated management, biopesticides may provide protection, being eco-friendly safe humans non-target organisms. Essential oils, complex mixtures...
ABSTRACT Introduction Nepeta species contain a variety of secondary metabolites, including iridoid monoterpenes – nepetalactones and phenolic acids that are considered the main bioactive constituents. This work represents first attempt to comparatively explore variations in these two major groups metabolites within genus. Objective To develop an efficient analytical methodology for simultaneous analysis methanol extracts selected species, evaluate its potential application chemotaxonomic...
Iridoids, a class of atypical monoterpenes, exhibit exceptional diversity within the Nepeta genus (subfam. Nepetoidae, fam. Lamiaceae).The majority these plants produce iridoids unique stereochemistry, with nepetalactones (NLs) predominating; however, few species lack compounds. By comparatively analyzing metabolomics, transcriptomics, gene co-expression, and phylogenetic data iridoid-producing N. rtanjensis Diklić & Milojević iridoid-lacking nervosa Royle Bentham, we presumed that...
In this work we present results of two significantly different types plasma treatment on Paulownia tomentosa Steud. seeds. the first type, seeds were directly treated in low‐pressure and then imbibed with distilled water. second an atmospheric pressure was used for obtaining activated water (PAW) which is imbibition The CAT activity protein content evaluated during 4 d following process, i.e., immediately after phytochrome activation 3 subsequent days. Comparison to control group allows...
β-cyclodextrin (β-CD) is a good host for the encapsulation of fennel and basil essential oils (FEO BEO, respectively) formation inclusion complexes (ICs) using co-precipitation method. According to results GC/MS analysis conducted in this study, monoterpenes monoterpenoids were dominant chemical groups total FEO, while these two occurred along with sesquiterpenes sesquiterpenoids. The presence compounds from both EOs was validated FT-IR spectra ICs, which indicated successful complexation....
In this paper, we will present results of plasma treatments meristematic cells Daucus carota. Plasma needle was used as an atmospheric pressure/gas composition source non-equilibrium in all treatments. Activity antioxidant enzymes superoxide dismutase and catalase measured immediately after treatment two weeks following the treatment. Superoxide activity increased samples On other hand, much higher treated when These show that there is a direct proof triggering signal transduction by...
The present study provides, for the first time, a physicochemical and biochemical characterization of redox processes associated with ripening Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) Imaging (EPRI) measurements reactive oxygen species (ROS) were performed in parallel tissue-specific metabolic profiling major antioxidants assessment antioxidant enzymes activity. Fruit transition from mature green (MG) to ripe red (RR) stage involved...
Nepeta nuda L., a notable medicinal species in the tradition of Balkan region, is rich source bioactive iridoids and phenolics previously described as high-resolution taxonomical classifiers for genus Nepeta. However, their potential investigating intra-species differentiation here first time. The aim was to recognize sources natural chemical diversity association with genetic variability both within among N. populations Central Balkans. Chemical assessed from methanol extracts essential...
Histone posttranslational modifications (PTMs) impart information that regulates chromatin structure and activity. Their effects are mediated by histone reader proteins bind specific PTMs to modify and/or recruit appropriate effectors alter the landscape. Despite their crucial juxtaposition between functional outcome, relatively few plant readers have been identified, nothing is known about impact on viral pathogenesis. We used geminivirus Cabbage leaf curl virus (CaLCuV) as a model...
Novel poly(methacrylic acid)/gelatin (PMAG) interpenetrating networks reinforced by different amounts of nanostructured particles hydroxyapatite (HA) (HA/polymer weight ratios from 0% to 40%) were synthesized. The introduction HA significantly enhanced mechanical properties, but slightly reduced swelling ability, pH sensibility and porosity. increase HA/polymer ratio 40% increased the compressive strength 29.83 (pure PMAG hydrogel) 68.16 kPa. Drug release behavior investigated in simulated...
Spiked centaury (Centaurium spicatum) is a well-known medicinal plant from the Mediterranean region with various bioactivities, but there are no studies addressing use of different solvent systems to improve its pharmacological potential. Nine extraction procedures were adapted study effects composition on content bioactive compounds in C. spicatum extracts and corresponding bioactivities. Targeted metabolomics was performed obtain information chemical extracts. Ethanol-water-based most...
The aim of this study was to determine intra- and interspecies variation in the qualitative quantitative composition methanol-soluble metabolites leaves three Digitalis species ( D. lanata , ferruginea grandiflora ) from central Balkans. Despite steady use foxglove constituents for human health as valuable medicinal products, populations genus Plantaginaceae have been poorly investigated describe their genetic phenetic variation. Following untargeted profiling using UHPLC-LTQ Orbitrap MS, by...
Extracts of the aerial (fronds) and underground parts (rhizome roots) Asplenium adiantum-nigrum L. ruta-muraria were analyzed for their phenolic composition antioxidant properties (scavenging capacities against DPPH• ABTS•+), comparatively assayed antimicrobial antibiofilm activity. Total 17 compounds, belonging to classes acids (hydroxybenzoic hydroxycinnamic acids), flavonoids (flavan-3-ols, flavonols), xanthones identified quantified using UHPLC/DAD/(–)HESI-MS/MS analysis. The present...
Most of the species from genus Centaurium Hill readily hybridize between themselves in natural habitats. Artificial interspecific hybrid plants were obtained under vitro conditions using reciprocal crosses 4 species: erythraea, C. littorale, maritimum, and pulchellum. Among 76 crossing experiments performed, 3 types produced seeds gave 20 plants. Nuclear DNA quantification, fingerprinting molecular markers, determination variation main secondary metabolite content employed to confirm their...
Introduction Plants respond to water stress with a variety of physiological and biochemical changes, but their response varies among species, varieties cultivars. Waterlogging in tomato reduces plant growth, degrade chlorophyll increase concentration oxidative parameters. Priming can alleviate plants caused by waterlogging enabling be more tolerant an additional the current or even subsequent generation. The aim this study was evaluate genotypes for sensitivity applied during early...
L. shares a typical secondary chemistry with other
The geographic distribution of Borrelia burgdorferi sensu lato species in Europe shows very dynamic spatial and temporal variations. Since different usually correlate with clinical manifestation Lyme borreliosis, knowledge the pathogen is important for understanding ecology epidemiology disease. Our previous studies, based on direct molecular methods, revealed high diversity B. s.l. complex unexpected prevalence lusitaniae Ixodes ricinus ticks from Serbia. aim present study was further...
A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method on amplification of 552 nucleotide bases long sequence 16S rRNA, targeted by specific primers. In the present study, total RNA extracted from Ixodes ricinus used as template. results showed higher sensitivity compared to standard dark-field microscopy. Method specificity confirmed cloning and sequencing obtained base pairs amplicons. Phylogenetic analysis...
When exposed to stressful conditions, plants produce numerous volatile organic compounds (VOCs) that have different biological and environmental functions. VOCs emitted during the rehydration process by fronds of desiccation tolerant fern Asplenium ceterach L. were investigated. Headspace GC–MS analysis revealed volatiles profile rustyback is mainly composed fatty acid derivatives: isomeric heptadienals (over 25%) decadienals 20%), other linear aldehydes, alcohols, related compounds. Aerial...
We have previously found apparent differences in Gpdh allele frequences between borrelia infected and uninfected Ixodes ricinus as revealed by native gel electrophoresis of allozyme polymorphisms. The present study deals with the genetic basis observed polymorphism. Multiple sequence alignment 36 open reading frames identified a total 40 polymorphic nucleotide sites. Of sites, 34 were silent (did not result amino acid residue change), while six active causing change chain. All sites situated...
In order to describe seasonal changes in Lyme diseases risk rate at three localities Serbia, during the period of 2003-2005, a total 1542 Ixodes ricinus ticks (493 nymphs, 525 females and 524 males) were examined. The prevalence Borrelia burgdorferi Bovan Lake County higher than average for European (45.9% adults 18.8% nymphs). Mt. Avala Kljajicevo counties nymphs were, respectively, infected following percentages: 26.3, 10.7; 16.2 7.6%. outcome indicates relatively high contracting disease...