A5107988875- Sensor Technology and Measurement Systems
- Advanced Sensor Technologies Research
- Advanced MEMS and NEMS Technologies
- Acoustic Wave Resonator Technologies
- Analytical Chemistry and Sensors
- Innovative Energy Harvesting Technologies
- Non-Invasive Vital Sign Monitoring
- Mechanical and Optical Resonators
- Advanced Sensor and Energy Harvesting Materials
- Energy Harvesting in Wireless Networks
- Magnetic Properties and Synthesis of Ferrites
- Multiferroics and related materials
- Advanced Fiber Optic Sensors
- Inhalation and Respiratory Drug Delivery
- Retinoids in leukemia and cellular processes
- Chemokine receptors and signaling
- Wireless Power Transfer Systems
- Hemodynamic Monitoring and Therapy
- Gas Sensing Nanomaterials and Sensors
- Fault Detection and Control Systems
- Balance, Gait, and Falls Prevention
- Receptor Mechanisms and Signaling
- Neonatal Respiratory Health Research
- Advanced Control Systems Design
- Ocular Surface and Contact Lens
National Institute of Technology Tiruchirappalli
2014-2024
Sri Sivasubramaniya Nadar College of Engineering
2024
Sri Ramachandra Institute of Higher Education and Research
2024
Forest Institute
2022-2023
Wake Forest University
2006-2023
University of Engineering & Management
2020
University of Oslo
1998
Objective To determine the effects of aging and oxidative stress on response human articular chondrocytes to insulin‐like growth factor 1 (IGF‐1) osteogenic protein (OP‐1). Methods Chondrocytes isolated from normal cartilage obtained tissue donors were cultured in alginate beads or monolayer. Cells stimulated with 50–100 ng/ml IGF‐1, OP‐1, both. Oxidative was induced using tert ‐butyl hydroperoxide. Sulfate incorporation used measure proteoglycan synthesis, immunoblotting cell lysates...
The human airways are complex structures with important interactions between cells, extracellular matrix (ECM) proteins and the biomechanical microenvironment. A robust, well-differentiated in vitro culture system that accurately models these would provide a useful tool for studying normal pathological airway biology. Here, we report development characterization of physiologically relevant air-liquid interface (ALI) 3D 'organ tissue equivalent' (OTE) model three novel features: native...
This paper presents modeling and experimental evaluation of a cantilever-based piezoelectric energy harvester with cavity. The introduction cavity in the beam shifts neutral axis away from surface element which turn increases strain generated voltage. voltage cantilever is higher when compared to without found vary its position thickness. analytical results are close agreement. generates 75% than
Systems using microcontrollers make the interface of a transducer with digital world much easier. They build smart, lucid, compact, cheap, and less power consuming electronic interfaces. Limited acquisition time is critical for many industrial applications. Single-element resistive sensors are used on large scale. An attempt has been made to reduce measuring system compared existing work which converts change in sensor resistance three charge–discharge cycles. Efforts have this paper two The...
Previously we reported that the G protein-coupled receptor (GPCR) agonist thrombin potentiated mitogenic effect of epidermal growth factor (EGF) on human airway smooth muscle (ASM) by promoting sustained late-phase activation PI3K and p70S6K via a pathway dependent Gbetagamma subunits heterotrimeric proteins. Here, provide additional mechanistic insight reveal robustness this phenomenon demonstrating H1 histamine thromboxane receptors utilize same mechanism to augment ASM specific protein...
Although G protein-coupled receptor (GPCR) kinases (GRKs) have been shown to mediate desensitization of numerous GPCRs in studies using cellular expression systems, their function under physiological conditions is less well understood. In the current study, we employed various strategies assess effect inhibiting endogenous GRK2/3 on signaling and endogenously expressed s-coupled receptors human airway smooth muscle (ASM) cells. inhibition by a Gbetagamma sequestrant, dominant-negative...
We have previously shown that retinoids inhibit activation of human peripheral blood B-lymphocytes. In the present paper, we wished to explore involvement nuclear retinoid-specific receptors in this process by using ligands specific for retinoic acid (RARs) and retinoid X (RXRs). found RAR-specific ligand TTAB reduced anti-IgM-induced B-cell a dose-dependent manner. Thus, at 100 nM TTAB, DNA synthesis was approximately 60%. contrast, RXR-selective SR11217 had no effect on synthesis. Similar...
A novel dual-slope resistance to digital converter (RDC) for compensating lead is presented. The RDC uses a analog-to-digital (ADC) structure along with three switches and diode. It completes measurement in one charging–discharging cycle only, hence provides an improvement existing RDCs based on direct microcontroller interfaces (DMIs), where two or cycles are required. Moreover, it incorporates the feature of compensation RDCs. scheme works by connecting resistive sensor input terminal...
In the present study, a modified limb lead (MLL) system was used to record Ta wave in sinus rhythm and with AV block male patients.Eighty subjects (mean age 36 ± 7 years) 20 patients 72 5 were included this study. Standard (SLL) ECGs MLL recorded for 60 seconds each an EDAN SE-1010 PC ECG system.In subjects, observable duration 109 4.7 ms, P-Ta 196 5.1 corrected 238 7.2 ms. The peak amplitude -42 8 µV. patients, 314 28 ms 418 29 46 31 while -37 9 A correlation found between P amplitude, no...
Objective: Continuous cuffless blood pressure (BP) monitoring research has emerged as is one of the dynamic parameters which reflects cardiac arrhythmias and rheological disorders without drawbacks current techniques. All existing measurement techniques are cuff-based with such being discontinuous in nature, uncomfortable for patient, etc. Therefore, goal to develop an algorithm estimate BP accurately using pulse transit time (PTT), photoplethysmogram intensity ratio (PIR) Womersley number...
In this proposed work, temperature sensors, namely, a thermocouple and thermistor were linearized using deep neural networks. The feedforward network (DFNN) technique was to linearize the K-type thermocouple's output, in given range −100 °C 1372 °C, while nonlinearity reduced from 2.03% 0.002% full scale span (FSS). Deep layer recurrent (DLR-NN) used reduce of negative coefficient (NTC) 84.63% 0.13% FSS. for cold junction compensation (CJC) thermocouple. both thermistor, linearization...
Adenoviral infection is a major risk factor for otitis media. We hypothesized that adenovirus promotes bacterial ascension into the middle ear through disruption of normal function in Eustachian tubes due to inflammation-induced changes. An intranasal model chinchilla was used test ability type 5 promote by Streptococcus pneumoniae. The hyperinflammatory mutant dl327 and nonreplicating H5wt300ΔpTP were role inflammation viral replication, respectively, promotion pneumococcal infection....
Nontypeable Haemophilus influenzae (NT Hi ) is an extremely common human pathobiont that persists on the airway mucosal surface within biofilm communities, and our previous work has shown NT maturation coordinated by production uptake of autoinducer 2 (AI-2) quorum signals. To directly test roles for AI-2 in maintenance biofilms, we generated 86-028NP mutant which luxS transcription was under control xylA promoter :: ), rendering inducible xylose.
Rare earth substituted strontium hexaferrite powders were synthesised through a molten salt route at 900°C for 5 h. The influence of rare-earth magnetic ion substitution on microstructural features, morphology and temperature-dependent properties was investigated. lattice parameter ratio less than 3.98 proves that all the samples primarily present phase. Fourier transform infrared peaks also confirmed presence metal-oxygen bond. A 66% increase in saturation, 38% coercivity more two-time...
A central hallmark of tumorigenesis is metabolic alterations that increase mitochondrial reactive oxygen species (mROS). In response, cancer cells upregulate their antioxidant capacity and redox-responsive signaling pathways. promising chemotherapeutic approach to ROS levels incompatible with tumor cell survival. Mitochondrial peroxiredoxin 3 (PRX3) plays a significant role in detoxifying hydrogen peroxide (H2O2). PRX3 molecular target thiostrepton (TS), natural product FDA-approved...