Maternal nutritional status influences the developmental environment of fetus which consequently affects birth weight newborn. However, association between maternal factors and is complex not well characterized in Ethiopia.To assess effect anthropometry biochemical profile on babies at Butajira Referral Hospital, Butajira, Ethiopia.Laboratory-based cross-sectional study was conducted among 337 pregnant women hospital. Socio-demographic obstetric characteristics were collected using...

Background There is a worldwide upscale in mass drug administration (MDA) programs to control the morbidity caused by soil-transmitted helminths (STHs): Ascaris lumbricoides, Trichuris trichiura and hookworm. Although anthelminthic drugs which are used for MDA supplied two pharmaceutical companies through donation, there wide range of brands available on local markets efficacy against STHs quality remain poorly explored. In present study, we evaluated albendazole (Bendex Ovis) market...

Malaria caused by Plasmodium vivax and falciparum is among the major public health problems in most endemic areas of world. Artemisinin-based combination therapy (ACT) has been recommended as a first-line treatment for uncomplicated malaria almost all regions. Since ineffectively regulated medicines resource limited settings could favour infiltration poor quality anti-malarial into pharmaceutical supply chain jeopardize positive outcome, regular monitoring critical. Thus, aim this study was...

Abstract Poor quality amoxicillin-clavulanate potassium tablets have been recently discovered in generic drugs related to Augmentin-like medicines containing amoxicillin and clavulanic acid, as well its derivatives falsified active ingredients. One of the most important dosage form characteristics are a detailed pharmaceutical ingredients dissolution release profile evaluation obtained through testing. The test is used development both brand-name drugs. Prior beginning bioequivalence...

Background: More than 80% of all common disease in Ethiopia is infectious origin. Traditional medicine plays a great role combating this disease. Dichrocepala integrifolia (L.f) O.kuntze one the traditional remedies used for treatment wound infection. Objective: To screen major phytochemical constituents and evaluate antibacterial activity tests leaf extracts Dichrocephala (L.f.) O. kuntze. Methods: experimental study involving gradient extraction, disc diffusion broth dilution were...

Dissolution is the critical quality control parameter and used to predict an in vivo oral bioavailability, it support bio-waiver.To evaluate compare dissolution profile of eight brands metformin HCL 500 mg tablets available Jimma town, Southwest Ethiopia.The study was conducted Ethiopia. Eight (seven one comparator) were included. The as per United States Pharmacopeia, compared by one-way ANOVA, model-dependent model-independent approaches.All included tablet complied with single-point...

Though there are reports about V. auriculifera antimicrobial activity, is not enough information its activity on some bacterial and fungal species. Besides, was no quantitative evaluation done for phytochemicals previously. Therefore, the main purpose of this research work to evaluate phenol flavonoid contents auriculifera.The objective study conduct a sequentially extracted leaf Vernonia Hiern.The leaves plant were cleaned with tap water air-dried. The grounded product subsequently by...

Lipoma of the intestine is one uncommon benign tumors alimentary tract first reported by Bauer in 1957. The peak incidence usually seen between 50 and 60 years age more commonly females. They are either asymptomatic or mildly symptomatic. occurrence symptoms mostly related to diameter lesion. We present a single center consecutive case three patients who had giant colonic lipomas presented with intussusception. Two cases for time an emergency condition: acute intestinal obstruction. mode...

The use of Antiretroviral therapy (ART) has become a standard care for the treatment HIV infection. restores immune function and reduces HIV-related adverse outcomes. However, failure erodes this advantage leads to an increased morbidity compromised quality life in patients. Thus, study aimed assess anti-retroviral associated factors among patients on first line ART at Mizan-Tepi University Teaching Hospital. A cross-sectional was undertaken adult patient who have been attending Clinic...

Background The incidence of hypertension in persons 25 years age and older is estimated to be 46% Africa, where it still very common. This concerning rate could explained by the pharmaceutical markets’ accessibility poor quality antihypertensive drugs. Thus, purpose this study was evaluate compare different brands Amlodipine Tablets Commercially available Jimma Town, South-western Ethiopia. Methods control test conducted from August 30, 2019 February 27, 2020 at University Laboratory Drug...

An inflammatory myofibroblastic tumor (IMT) is an uncommon solid neoplasm of mesenchymal origin. They are usually seen in children and adolescents commonly affect the lung, but they can nearly arise from every organ. The prevalence IMT small bowel very rare. tumors have generally a benign clinical course, with some risk local recurrence or distant metastasis. This 55-year-old male patient who presented intermittent abdominal pain, vomiting ingested matter loss appetite for 2 weeks duration....

Background: WHO report of 2017 estimates that the rates substandard and falsified medical products in low- middle-income countries is approximately 10.5% with an estimated spend US$ 30.5 billion.Objective: The purpose study to assess quality different brands metronidazole available Jimma town, Oromia region, South West Ethiopia.Methods: Cross-sectional was conducted regional state, Ethiopia. from May 03 – July 30, 2018. Samples were collected using convenience sampling technique. samples...

Abstract Back-ground : Poor quality Amoxicillin-clavulanate potassium tablets have been recently discovered in generic drugs related to Augmentin-like medicines containing amoxicillin and clavulanic acid, as well its derivatives falsified active ingredients. One of the most important dosage form characteristics is a detailed API dissolution profile obtained through testing. The test used development both brand-name drugs. Prior beginning bioequivalence studies, it critical compare profiles...

Abstract Back-ground : Poor quality Amoxicillin-clavulanate potassium tablets have been recently discovered in generic drugs related to Augmentin-like medicines containing amoxicillin and clavulanic acid, as well its derivatives falsified active ingredients. One of the most important dosage form characteristics is a detailed API dissolution profile obtained through testing. The test used development both brand-name drugs. Prior beginning bioequivalence studies, it critical compare profiles...

Poor quality medicines include substandard and falsified (i.e. counterfeited) medicines. WHO report of 2017 estimates that the rates medical products in low- middle-income countries is approximately 10.5% with an estimated spend US$ 30.5 billion

Background: Poor quality medicines include substandard and falsified (i.e., counterfeited) medicines. WHO report of 2017 estimates that the rates medical products in low- middle-income countries is approximately 10.5% with an estimated spend US$ 30.5 billion. Objective: The purpose study to assess different brands metronidazole available Jimma town, Oromia region, South West Ethiopia. Methods: Cross-sectional was conducted regional state, Ethiopia. from May 03 – July 30, 2018. Samples...