About
Contact & Profiles
A5102868580
Research Areas
- Organoselenium and organotellurium chemistry
- Synthesis and biological activity
- Ferrocene Chemistry and Applications
- Genomics, phytochemicals, and oxidative stress
- Redox biology and oxidative stress
Mansoura University
2021
10.1016/j.bioorg.2021.104713
article
EN
Bioorganic Chemistry
2021-02-09
Hepatocellular carcinoma is a highly aggressive and difficult-to-treat type of cancer. Incorporating urea functionality into the backbone organoselenium compounds expected to develop promising chemotherapeutic leads against liver Methods: Urea-functionalized were synthesized in good yields, their cytotoxicity was evaluated HepG2 cells. Results: 1,1'-(Diselanediylbis(4,1-phenylene))bis(3-phenylurea) (14) exhibited efficient anti-HepG2 activity sub-micromolar concentrations, with no toxicity...
10.4155/fmc-2021-0114
article
EN
Future Medicinal Chemistry
2021-08-24
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