A5057383266- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- COVID-19 Clinical Research Studies
- Virology and Viral Diseases
- Studies on Chitinases and Chitosanases
- Viral Infections and Immunology Research
- Viral Infections and Outbreaks Research
- HIV/AIDS Research and Interventions
- Respiratory viral infections research
- Malaria Research and Control
Universidade de São Paulo
2020-2025
Research Institute for Tropical Medicine
2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021-2023
Instituto de Medicina Avançada
2020
The COVID-19 pandemic has highlighted the critical need for scalable, rapid, and cost-effective diagnostic solutions, especially in resource-limited settings. In this study, we developed a sustainable magnetic electrochemical biosensor mass testing of SARS-CoV-2, emphasizing affordability, environmental impact reduction, clinical applicability. By leveraging recycled materials from spent batteries plastics, achieved circular economy-based fabrication process with recyclability rate 98.5%....
Yellow fever virus (YFV) was detected in two distinct geographic locations Sao Paulo State, Brazil, between September 2024 and February 2025. Phylogenetic analysis of six new genomes revealed a re-introduction 2022 from Midwest Brazil followed by persistence state. Continued surveillance neotropical primates is required to prevent cases humans.
Introduction—The dynamics of SARS-CoV-2 shedding and replication in humans remain incompletely understood. Methods—We analyzed from multiple sites individuals with an acute COVID-19 infection by weekly sampling for five weeks 98 immunocompetent 25 immunosuppressed individuals. Samples culture supernatants were tested via RT-PCR to determine viral clearance rates vitro replication. Results—A total 2447 clinical specimens evaluated, including 557 nasopharyngeal swabs, 527 saliva samples, 464...
Background Chikungunya-fever (CHIKF) remains a public health major issue. It is clinically divided into three phases: acute, post-acute and chronic. Chronic cases correspond to 25–40% individuals and, though most of them are characterized by long-lasting arthralgia alone, many exhibit persistent or recurrent inflammatory signs that define post-Chikungunya chronic joint disease (pCHIKV-CIJD). We aimed identify early clinical markers evolution pCHIKV-CIJD during acute phases....
Chikungunya (CHIK) is a debilitating mosquito-borne disease with an epidemiology and early clinical symptoms similar to those of other arboviruses-triggered diseases such as dengue or Zika. Accurate rapid diagnosis CHIK virus (CHIKV) infection therefore challenging. This international study evaluated the performance automated VIDAS® anti-CHIKV IgM IgG assays compared that manual competitor ELISA for detection antibodies in 660 patients suspected CHIKV infection. Positive negative agreements...
In Brazil, Dengue, Zika and Chikungunya viruses constitute a major threat to the public health system. Simultaneous circulation of these arboviruses occurs in many regions world due expansion transmission vectors. The infection by triggers similar symptoms during their acute phase. However, some cases, severe may occur, leading different types disabilities even death. this context, considering similarity symptoms, problems caused arboviruses, increasing risk coinfection humans, differential...
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The ongoing COVID-19 pandemic continues to have a significant impact on our daily lives, necessitating the rapid development of early diagnostic tools mitigate emergence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks. In this context, biosensor technology has emerged as highly promising strategy address challenges low sensitivity, specificity, and high cost associated with clinical diagnosis. study, we present novel cost-effective approach for detection SARS-CoV-2...
Abstract Background COVID-19 disease (Coronavirus 2019) caused by SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) is widespread worldwide, affecting more than 11 million people globally (July 6 th , 2020). Diagnostic techniques have been studied in order to contain the pandemic. Immunochromatographic (IC) assays are feasible and low cost alternative for monitoring spread of population. Methods Here we evaluate sensitivity specificity eleven different immunochromatographic tests...
COVID-19 disease is spread worldwide and diagnostic techniques have been studied in order to contain the pandemic. Immunochromatographic (IC) assays are feasible a low-cost alternative especially low middle-income countries, which lack structure perform certain techniques. Here we evaluate sensitivity specificity of eleven different IC tests 145 serum samples from confirmed cases using RT-PCR 100 negative blood donors collected February 2019. We also evaluated cross-reactivity with dengue 20...
Infecções pelo vírus Chikungunya (CHIKV) podem frequentemente resultar no desenvolvimento de Doença Articular Inflamatória Crônica pós-Chikungunya (pCHIKV-CIJD). Essa condição gera impactos na qualidade vida dos pacientes e nos gastos com a saúde pública. Neste estudo, visamos identificar mecanismos moleculares precocemente envolvidos evolução para pCHIKV-CIJD. Pacientes em fase aguda chikungunya foram incluidos uma coorte prospectiva tiveram o seguimento 90 dias. Aqueles que permaneceram...
Introduction- The dynamics of SARS-CoV-2 shedding and replication in humans remain incompletely understood. Methods- We analyzed from multiple sites individuals with an acute COVID-19 infection by weekly sampling for five weeks 98 immunocompetent 25 immunosuppressed individuals. Samples culture supernatants were tested RT-PCR to determine viral clearance rates vitro replication. Results- A total 2447 clinical specimens evaluated, including 557 nasopharyngeal swabs, 527 saliva samples, 464...
The recognition of the causal association between Zika virus (ZIKV) infection during pregnancy and congenital abnormalities including microcephaly underlines importance preventing this disease in pregnant women (PW) childbearing age (WCA). Although Brazil other Latin American countries reported a significant reduction number ZIKV infections recent years, epidemic waves can recur settings with previous outbreaks as conditions for transmission remain optimal susceptible populations are...