- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Consumer Attitudes and Food Labeling
- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Eosinophilic Esophagitis
- Protein Hydrolysis and Bioactive Peptides
- Agricultural safety and regulations
- Child Nutrition and Feeding Issues
- Food Safety and Hygiene
- Infant Health and Development
Bambino Gesù Children's Hospital
2019-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024
Vatican Secret Archives
2018
The use of eliciting doses (EDs) for food allergens is necessary to inform individual dietary advice and allergen risk-management. Eliciting Dose 01 (ED01) milk egg, calculated from populations allergic subjects undergoing oral challenges (OFCs), are 0.2 mg total protein. respective 05 (ED05) 2.4 2.3 egg. As about 70% children such foods may tolerate them when baked, we sought verify the EDs that subpopulation egg-allergic children.We retrospectively assessed consecutive OFC fresh egg...
The frequency and severity of reactions in food-allergic consumers exposed to unintentional food allergen contamination during production is unknown. To warn allergic consumers, it has been suggested for pre-packaged foods be precautionary labelled when the may exceed amount which 1%-5% population could react (ED01-ED05). ED01 hazelnut milk have estimated at 0.1 0.2 mg, respectively, by Voluntary Incidental Trace Allergen Labelling (VITAL) initiative. respective reference doses recommended...
Abstract Background In Europe, Omalizumab (anti‐IgE) is indicated for the treatment of moderate to severe asthma, but not IgE‐mediated food allergy (FA). Objective We assessed impact on efficacy, safety, and quality life (FA‐QoL) in patients with asthma who have a history anaphylaxis peanut, tree nuts, fish, egg, milk, and/or wheat. Methods Food‐allergic children (6–18 years) underwent oral challenges (OFCs) establish threshold reaction culprit food(s) at baseline (T0) 4‐month intervals (T1,...
Purpose of review The purpose this is to provide an overview the perspectives regarding precautionary allergen labelling (PAL) prepackaged foods following consultation conducted by Food and Agriculture Organization (FAO) WHO. Recent findings FAO/WHO provided a comprehensive assessment current status practices PAL implementation worldwide. One key highlighted Expert Committee was need for improvement in existing systems. It noted that many countries lacked uniformity practices, leading...
Background : In Europe, Omalizumab (anti-IgE) is indicated for the treatment of moderate/severe asthma, but not IgE-mediated food allergy (FA). Objective We prospectively assessed impact efficacy, safety, and quality life (FA-QoL) in patients with asthma history anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or wheat. Methods Food-allergic children (6-18yrs) underwent oral challenges (OFCs) establish threshold reaction culprit food(s) at baseline (T0) four-month intervals (T1, T2,...
Extremely sensitive food-allergic patients may react to very small amounts of allergenic foods. Precautionary allergen labelling (PAL) warns from possible contaminations. We evaluated by oral food challenge the reactivity a brand PAL-labelled milk- and egg-free biscuits children with severe milk egg allergy. explored ability proteomic methods identify minute milk/egg allergens in such biscuits. Traces and/or were measured two different liquid-chromatography-mass spectrometry methods. The...
Extremely sensitive food-allergic patients may react to very small amounts of allergenic foods. Precautionary allergen labelling (PAL) warns from possible contaminations. We explored the ability proteomic methods identify minute milk/egg allergens in a brand PAL-labelled milk- and egg-free biscuits. evaluated reactivity children with severe milk egg allergy, by oral food challenge. Traces and/or biscuits were measured two different liquid-chromatography-mass spectrometry methods. The binding...
In multiple food allergy, the avoidance of offending foods reduces patient’s and his family’s quality life. Biologics (omalizumab) represent most promising approach1, but serum IgE levels > 1,500 kUI/L may limit their use. immunoapheresis be used to decrease improve patients’ conditions2. We aim assess efficacy on tolerance clinical status children with asthma allergy. this prospective, open label study (IAO, ImmunoApheresis for Omalizumab; OPBG EC approval 599/18), we evaluated severe...
Background. The use of eliciting doses (EDs) for food allergens is necessary to inform individual dietary advice and allergen risk-management. Eliciting Dose 01 (ED01) milk egg, calculated from populations allergic subjects undergoing diagnostic Oral Food Challenges (OFCs), are 0.2 mg total protein. respective 05 (ED05) 2.4 2.3 egg. As about 70% children such foods may tolerate them when baked, we sought verify the EDs that subpopulation egg-allergic children. Methods. We retrospectively...