A5000953051- Glioma Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Cervical Cancer and HPV Research
- Cancer-related molecular mechanisms research
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Head and Neck Anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Oral and Maxillofacial Pathology
- Cardiac tumors and thrombi
- Ear and Head Tumors
- Neurofibromatosis and Schwannoma Cases
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Urologic and reproductive health conditions
- Meningioma and schwannoma management
- Epigenetics and DNA Methylation
- Lung Cancer Treatments and Mutations
- CNS Lymphoma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
Instituto Nacional de Cancerología
2016-2025
Clínica Santa María
2017-2023
Universidad Nacional de Colombia
2013-2023
Medico
2023
Moffitt Cancer Center
2023
University of Palermo
2011
Universidad De Santander
2010
Infant
1999
Hospital Materno-Infantil
1999
Clinical parameters and proteins have recently been suggested as possible causes of radiotherapy (RT) resistance in cervical carcinoma (CC). The objective the present study was to validate prognostic biomarkers radiation resistance. prospective included patients undergoing RT with curative intent for histologically proven locally advanced squamous cell CC. Tissues blood samples were systematically collected before initiation. Immuno-histochemistry performed (IGF-IR α β, GAPDH, HIF-1 alpha,...
Background: Ectopic thyroid tissue is usually found anywhere along the embryonic descent pathway of medial anlage from tongue to trachea (Wölfler area). However, ectopic in adrenal gland (ETTAG) not easy understand on basis embryology; because it so rare, possibility metastasis should first be considered. Here, we describe two cases ETTAG with pathogenetic implications and review associated literature. Patient findings: Two presented as incidental cystic masses adult females, one having a...
To determine the correlation between results of thyroid fine-needle aspirations interpreted using Bethesda system and final histopathological reports for patients at an oncology hospital (OH) non-oncology hospitals (NOHs).A retrospective, cross-sectional, descriptive study was performed to compare cytology histopathology with nodules in three Colombian hospitals. The diagnoses two methods is reported. In Colombia, health provides existence general care specializing cancer.A total 196 were...
Gliosarcoma is a rare central nervous system (CNS) neoplasm with biphasic glial and non-glial malignant components. Here we describe the radiologic histopathologic features observed in five cases of primary gliosarcoma. The mean age at diagnosis studied patients was 54.2 years; these were predominantly males (male:female ratio = 4:1). At all had several clinical deterioration. most common symptoms presentation were: headache (5/5 cases), seizures (4/5 cases) hemiparesis (1/5 cases). All...
High hypoxic, glycolytic and acidosis metabolisms characterize cervical cancer tumors have been described to be involved in chemoradioresistance mechanisms. Based on these observations, the present study assessed four selected novel biomarkers prognosis of locally advanced carcinoma. A total 66 patients with stage IIB/IIIB were retrospectively included. The protein expression levels glucose transporter 1 (GLUT1), carbonic anhydrase 9 (CAIX) hexokinase (HKII) investigated by...
Background Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal dominant disorder marked by pathogenic variants in the MEN1 tumor suppressor gene, leading to tumors parathyroid glands, pancreas, and pituitary. The occurrence of ACTH-producing pancreatic neuroendocrine carcinoma exceedingly rare MEN1. Case presentation This report details a Colombian family harboring novel variant identified through genetic screening initiated index case. Affected members exhibited primary...
Desmoplastic infantile ganglioglioma (DIG) is a rare supratentorial tumor in the central nervous system. Definitive diagnosis of this neoplasm based on histopathologic analysis evaluating distinctive findings such as fibroblastic differentiation. Here we present clinical case DIG with long follow-up an eight-year-old boy six-month history recurrent emesis, psychomotor hyperactivity and generalized tonic-clonic seizures. Computed tomography scan magnetic resonance imaging (MRI) showed cystic,...
This article is a preliminary investigational study that aimed at giving hints about the interesting biomarkers involved in transition process from low-grade cervix lesion to invasive cervical cancer. Our focuses on risk factors and tumour molecular changes one patient. First 1986, she was diagnosed preinvasive lesion. Then, 16 years later, an The 2002 diagnosis squamous cell carcinoma of cervix, stage IIIB (FIGO), whereas had been high-grade intraepithelial Retrospectively, analysis samples...
Introduction: Thyroid cancer is the most common endocrine neoplasia and papillary subtype frequent; there are histological clinical factors associated with a higher risk of recurrence metastasis.Objective: The aim this study was to examine histological, prognostic characteristics thyroid carcinomas diagnosed at National Cancer Institute Colombia.Materials methods: A retrospective cohort carried out on 619 patients carcinoma between 2006 2012; we analyzed sociodemographic,...
Introduction. Neoplasms originating from the urachus are rare. The most common urachal malignancy is adenocarcinoma, whereas extragonadal germ cell tumors, primarily of urachus, an extremely rare finding. Objective. To describe a primary yolk sac tumor (YST) in adult. Case report. A 44-year-old woman presented with 6 months pelvic pain associated sensation progressive mass growth. At time resection, was found to be attached by pedicle dome bladder, no injury adjacent organs. Pathological...
Background: Few studies have analyzed the association between human telomerase reverse transcriptase (hTERT) protein expression (nuclear and cytoplasmic localization), hTERT methylation status, papillomavirus (HPV) genotype infection in cervical cancer. Patients Methods: One hundred seventy-three patients with cancer were analyzed. was detected by immunohistochemistry. DNA analysis performed using a PCR-RLB-hTERT assay, targeting two regions of promoter. Type specific HPV GP5+/GP6+PCR-RLB....
localizada en el polo inferior del riñón izquierdo, por lo cual, se realizó una biopsia renal, la que evidenció un tumor maligno indiferenciado, cuyos estudios de inmunohistoquimica sugerían los diagnósticos neuroectodermico primitivo Vs SS.Con anterior, iniciaron quimioterapia y realizaron nefrectomía radical.
Resumen Objetivo Determinar la expresion de CAIX, GLUT-1, HKII y establecer si existe asociacion entre respuesta temprana al tratamiento en carcinomas escamocelulares cuello uterino. Sujetos metodos En este estudio tipo cohorte retrospectiva se incluyo a 66 pacientes estadios FIGO IIB IIIB durante el periodo del 2001 2007, con una edad promedio 47 anos. De las pacientes, 22 fueron tratadas radioterapia exclusiva 44 quimioterapia concomitante radioterapia. La proteinas GLUT-1 fue determinada...
Solid cell nests (SCNs) of the thyroid are single or multiple foci solid and/or cystic clusters squamoid cells (main cells) with a minor proportion C-cells, found in normal thyroid. The SCNs have also been reported heart as an ultimobranchial heterotopia. Here, authors describe case thyroid-type associated struma ovarii. Main were positive for simple and stratified epithelial-type cytokeratins, carcinoembryonic antigen, carbohydrate antigen 19.9, p63, bcl-2, galectin-3. neuroendocrine...