SummaryIt is shown that exudative diathesis in the chick, produced by vit. E-free Torula yeast diets, prevented crude sources and purified fractions of Factor 3. Selenium, recently identified as integral part 3, was highly active. Protection obtained with 10 μg selenium per 100 g diet form seleno-cystathionine or sodium selenite; 200 elemental also were effective. All 3 forms element stimulated growth.

IN 1962 the Subcommittee on Poultry Nutrition of National Research Council (N.A.S.-N.R.C, 1962) revised its recommended calcium requirement for laying hens. A level 2.75% was adopted as new recommendation, based many reports indicating need more than 2.25% previously recommended. The also in fifth edition Nutrient Requirements 1966). However, Peterson et al. (1960) reported that a at least 3.4% necessary maximum egg shell quality. They noted environmental temperature had an important...

In response to stress, cancer cells generate nutrients and energy through a cellular recycling process called autophagy, which can promote survival tumor progression. Accordingly, autophagy inhibition has emerged as potential treatment strategy. Inhibitors targeting ULK1, an essential early regulator, have provided proof of concept for this kinase inhibit autophagy; however, these are limited individually in their potency, selectivity, or activity. study, we report two small molecule ULK1...

DURING the 13 years since discovery of nutritional need for selenium in diets rats (Schwarz and Foltz, 1957) chicks, (Scott et al, 1957; Stokstad al., numerous studies conducted on have shown that addition to preventing dietary liver necrosis vitamin E-deficient exudative diathesis is needed prevent myopathies heart skeletal muscles calves lambs, gizzard turkeys, atrophy fibrosis pancreas chicks. While most these selenium-responsive diseases also are responsive E, degeneration chick...

Woods (1) has shown that p-aminobenzoic acid (PABA) antagonizes the sulfanilamide inhibition of bacterial growth.Lampen and Jones (2) found pteroylglutamic (folic acid) related compounds are also active antagonists sulfonamide certain microorganisms.They concluded from their results t,he growt,h by sulfonamides was caused interference in synthesis folic at PABA site molecule.The studies reported t,his paper demonstrate growth bacteria is likewise obtained with pterinsl structurally to...

COTTONSEED meal has been used for many years in ruminant rations. Until recently, however, its use poultry diets curtailed. Cottonseed a number of undesirable characteristics: it contains gossypol and gossypol-like pigments cyclopropene fatty acids, is deficient lysine (Phelps, 1966). Moreover, the phytin cottonseed shown to interfere with utilization various minerals, particularly zinc (Lease Williams, 1967), calcium (Pensack et al, 1958; O'Dell al., 1958) phosphorus (Kastelic Forbes, 1961;...

LIMITED experimental evidence and field observations with chickens indicate that a possible relationship may exist between the requirement for vitamin A or carotene in diet, coccidiosis. Jungherr (1945) noted relatively high association occurrence of hypovitaminosis cecal However, he indicated have been coincidental. Taylor et al. (1946) also found when conditions were favorable development coccidiosis severity disease was enhanced receiving less than minimum A. Davies (1952)) suffering from...

THREE causal factors can be applied to an interdisciplinary approach the determination of food preferences (Scott, 1948; Woods 1949a, b): (1) Physiologists, biochemists and nutritionists tend emphasize effect organic need on choice, directing their experimental work search for mechanisms which direct food-getting behavior in order maintain a steady state with regard any necessary component (Richter, 1947; Lepkovsky, Hollander, 1955). (2) In some cases it appears that are completely...

EARLIER reports from this laboratory (Scott 1950Scott 1951a, 1951b, 1952) have presented results showing that an enlarged hock disorder in young poults occurring when these are fed a diet containing 2 to 4 percent of cod liver oil can be prevented by supplementation the with 5 10 dried brewers’ yeast. Because findings suffering exhibited marked creatinuria and reduction muscle creatine, plus fact was aggravated addition diet, it suggested condition might form nutritional muscular dystrophy....

In recent experimental work on the substitution of soybean meal in chick rations for meat scrap and fish meal, a study was made effect upon growth bone development omitting supplementary phosphorus from which contained no animal protein feedstuffs. Two basal were fed this work. Ration 1 composed 2 percent yellow corn 25 crushed wheat, 10 ground oats, 5 dehydrated alfalfa 30 0.5 B-Y feed, pulverized limestone, iodized salt, plus 100 A.O.A.C. units vitamin D per grams form activated sterol. 2,...

Introduction: The designer benzodiazepine (DBZD) market continues to expand whilst evading regulatory controls. widespread adoption of social media by pro-drug use communities encourages positive discussions around DBZD use/misuse, driving demand. This research addresses the evolution three popular DBZDs, etizolam (E), flubromazepam (F), and pyrazolam (P), available on drug for over a decade, comparing quantitative chemical analyses tablet samples, purchased from internet prior...

THE nature of the carotenoid pigments (xanthophylls) which are deposited in beak, shank and adipose tissues chickens yolks eggs, methods their measurement, effects antioxidants upon utilization, have been studied recently by Marusich et al. (1960); Bunnell (1962); Sullivan Holleman Madiedo (1964a,b); Bornstein Bartov (1966); (1966), others. Following synthesis quantity, according to method Isler (1958), β-apo-8′-carotenal canthaxanthin, crystalline samples these materials became available...

Dietary polychlorinated biphenyls (PCBs), DDT and related compounds, in well controlled experiments, produced no detrimental effects upon egg shell quality Single Comb White Leghorm chickens or Japanese quail. PCBs caused some decrease production a drastic reduction hatchability chickens, but not Inorganic mercury as HgSO4 HgCl2, at dietary levels up to 200 p.p.m. of Hg, had only small effects, if any, production, hatchability, quality, morbidity mortality. However, methyl chloride which...

IN A REVIEW of the amino acid requirements chicken, Almquist (1952) reported that sulfur requirement appeared to be 0.8% a diet containing 20% protein. This is present National Research Council (1954). also stated for methionine and other essential acids increased as protein content increased, but not same extent. He further noted approximately 0.1% more required in maximum efficiency feed utilization than growth. Hill (1953) reviewed cystine chick concluded agreement with total did exceed...