A5045165124- Muscle Physiology and Disorders
- Nutrition and Health in Aging
- Vitamin C and Antioxidants Research
- Muscle activation and electromyography studies
- Body Composition Measurement Techniques
- Sports injuries and prevention
Shirley Ryan AbilityLab
2021-2024
Abstract Background Progressive functional decline is a key element of cancer-associated cachexia. No therapies have successfully translated to the clinic due an inability measure and improve physical function in cachectic patients. Major barriers translating pre-clinical include lack cancer models that accurately mimic use non-specific outcome measures function, like grip strength. New approaches are needed investigate cachexia-related at both basic clinical science levels. Methods Survival...
Progressive functional decline is a key element of cancer-associated cachexia. Major barriers to translating preclinical therapies into the clinic include lack cancer models that accurately mimic decline, which develops over time, and use nonspecific measures, like grip strength, as surrogates for physical function. In this study, we aimed extend survival longevity model, investigate cachexia-related function at basic science level. Survival extension studies were performed by testing...