- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Cervical and Thoracic Myelopathy
- Dental Implant Techniques and Outcomes
- Titanium Alloys Microstructure and Properties
- Scoliosis diagnosis and treatment
- Spinal Hematomas and Complications
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Orthopedic Infections and Treatments
- Medical Imaging and Analysis
- Dental materials and restorations
- Bone fractures and treatments
- Management of metastatic bone disease
- Bone Tumor Diagnosis and Treatments
- Additive Manufacturing and 3D Printing Technologies
- Additive Manufacturing Materials and Processes
- Infectious Diseases and Tuberculosis
- Hip disorders and treatments
- Sarcoma Diagnosis and Treatment
- Spondyloarthritis Studies and Treatments
- Spinal Dysraphism and Malformations
- Case Reports on Hematomas
Kyoto University
2016-2025
Shiga Medical Center
2025
Kyoto University Hospital
2008-2025
Nishikawa Hospital
2024-2025
Research Organization of Information and Systems
2021-2025
Japan Agency for Medical Research and Development
2021-2023
Kitasato University
2023
Nagoya University
2019-2023
Graduate School USA
2023
Kudanzaka Hospital
2021
Abstract The apatite‐forming ability of titania gels with different structures has been investigated in a simulated body fluid ion concentrations nearly equal to those human blood plasma. Titania an amorphous structure or anatase rutile were prepared by the sol‐gel process subsequent heat treatment at various temperatures. did not induce apatite formation on their surfaces , whereas induced surfaces. deposition was more pronounced than gels. This indicates that specific is effective inducing...
Prospective consecutive clinical study to assess the decompressive benefit and outcome of oblique lateral interbody fusion for lumbar degenerative diseases.To evaluate radiologically effect distraction upon neural patency via an anterolateral retroperitoneal approach treatment diseases.Traditional symptomatic stenosis uses direct posterior decompression with or without fusion. Symptoms radiculopathy neurological claudication may also be alleviated indirectly through restoration...
Postoperative outcomes of cervical pedicle screw (CPS) placement were evaluated. The screws inserted in degenerative vertebrae using anatomic landmarks.To evaluate the risks this procedure caused by misplacements and subsequent complications.The CPS gives superior vertebral fixation but causing artery spinal cord injury. However, few clinical reports have been published concerning misplacement complications. Therefore, risk is still unclear.There 18 consecutive patients, who submitted to...
The precise biological characteristics of human mesenchymal stem cells (hMSCs), including growth regulatory mechanisms, have not yet been defined. Using 29 strains hMSCs isolated from bone marrow, we performed extensive analyses the profiles in vitro. All stopped proliferating with a mean population doubling (PD) 28, although there was considerable difference among strains. telomere restriction fragment length passaged twice correlated well final number PDs each strain, suggesting value this...
Retrospective survey.To clarify the present incidence and management of iatrogenic vertebral artery injury (VAI) during cervical spine surgery.VAI is a rare complication surgery, but it may be catastrophic. Anterior decompression (ACD) posterior atlantoaxial transarticular screw fixation (Magerl fixation) have been main causes, with reported incidences 0.3% to 0.5% 0% 8.2%, respectively. Popular new surgical techniques, such as pedicle or C1 lateral mass fixation, also entail potential risk...
In Brief Study Design. We evaluated the trajectories of atlantoaxial transarticular and C2-pedicle screws in 3 dimensions using computerized tomography. Objective. To compare anatomic risk for vertebral artery injury associated with screws. Summary Background Data. The fixation technique C1-lateral mass combined is considered a safer preventing than fixation. However, few reports have compared that Methods. A total 62 consecutive patients cervical lesions were 3-dimensional images...
Study Design. Retrospective nationwide questionnaire-based survey of complications. Objective. To elucidate the incidence complications and risk factors associated with lateral interbody fusion (LIF). Summary Background Data. After its introduction to Japan in February 2013, numbers LIF cases have increased substantially because advantages this minimally invasive procedure. However, has potential several unique Although there are many reports complications, no been conducted. Methods....
In Brief Study Design. A retrospective clinical study. Objective. To confirm the impact of O-C2 angle on dyspnea and dysphagia after posterior occipitocervical (O-C) fusion. Summary Background Data. Dyspnea are complications O-C fusion with malalignment, may be prolonged or occasionally serious. However, it is difficult to select a safe alignment during surgery, no indicators appropriate have been available preclude these complications. Methods. The authors retrospectively reviewed 29...
Ossification of the posterior longitudinal ligament (OPLL) can cause severe and irreversible paralysis in not only cervical spine but also thoracolumbar spine. To date, however, prevalence distribution OPLL whole has been precisely evaluated patients with OPLL. Therefore, we conducted a multi-center study to comprehensively evaluate using multi-detector computed tomography (CT) images analyze what factors predict presence ossified lesions who were diagnosed by plain X-ray. Three hundred...
Abstract In cementless fixation systems, surface character is an important factor. Alkali and heat treatments of titanium metal have been shown to produce strong bonding bone a higher ongrowth rate. this study we examined the effect alkali on rods in intramedullary rabbit femur model, regard hip stem. The implant were 5 mm diameter 25 length. Half implants immersed mol/L sodium hydroxide solution heated at 600°C for 1 h (AH implants), other half untreated (CL implants). implanted into distal...
Abstract NaOH and heat treatments of titanium metal induce an apatite‐forming ability on the by producing a bioactive graded sodium titanate structure its surface. An enhancement induced treatment was attempted conjoining water treatments. These are assumed to convert into anatase, which is presumed be more effective for apatite nucleation. The gel formed from shown transform anatase simple immersion in pure water, with subsequent Forming significantly improved simulated body fluid (SBF)....
A macroporous titanium surface layer is often formed on and alloy implants for morphological fixation of the to bone via bony ingrowth into porous structure. The metal was recently shown become highly bioactive by being subjected 5.0 M-NaOH treatment at 60°C 24 h subsequent heat 600°C 1 h. In present study, NaOH treatments were applied a substrate plasma spraying method. produced an uniform amorphous sodium titanate titanium. induced bonelike apatite formation in simulated body fluid early...
As reported previously, bioactive titanium is prepared by simple alkali and heat treatment, can bond to living bone directly. The purpose of this study was accelerate the bioactivity in vivo. In vitro study, sodium removal hot water immersion enhanced apatite-forming ability simulated body fluid dramatically. specific anatase structure titania gel effective for apatite formation vitro. current we investigated vivo effect on bone-bonding strength titanium. Sodium-free plates were an aqueous...
In Brief Study Design. Retrospective multi-institutional study Objective. To describe the surgical outcomes in patients with ossification of posterior longitudinal ligament thoracic spine (T-OPLL) and to clarify factors related outcomes. Summary Background Data. Detailed analyses T-OPLL have been difficult because rarity this disease. Methods. The subjects were 154 who surgically treated at 34 institutions between 1998 2002. procedures laminectomy 36, laminoplasty 51, anterior decompression...