A5078000036- Enzyme Structure and Function
- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- 2D Materials and Applications
- Enzyme Production and Characterization
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Community Ecology and Physiology
- Protein Structure and Dynamics
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Genomics and Phylogenetic Studies
- Toxin Mechanisms and Immunotoxins
- Adsorption and biosorption for pollutant removal
- Photosynthetic Processes and Mechanisms
- Genetics, Aging, and Longevity in Model Organisms
- Biochemical and Structural Characterization
- Evolution and Genetic Dynamics
- Electrochemical Analysis and Applications
- Chemical Synthesis and Analysis
- Nanoplatforms for cancer theranostics
- Evolutionary Game Theory and Cooperation
- Transgenic Plants and Applications
- Biochemical and Molecular Research
- Supramolecular Self-Assembly in Materials
- Computational Drug Discovery Methods
Manipal University Jaipur
2015-2025
Manipal Academy of Higher Education
2021-2022
Brookhaven National Laboratory
2010-2011
Indian Institute of Science Bangalore
2002-2007
Background: In the current scenario, synthesis of nanoparticles (NPs) using environmentally benign methods has gained significant attention due to their facile processes, cost-effectiveness, and eco-friendly nature. Methods: present study, copper oxide (CuO NPs) were synthesized aqueous extract Coelastrella terrestris algae as a reducing, stabilizing, capping agent. The CuO NPs characterized by X-ray diffraction (XRD), UV-visible spectroscopy (UV-Vis), Fourier transform infrared (FTIR),...
The green synthesized hybrid nanocomposite CS/CMC/BN/CuO NC exhibited remarkable photocatalytic efficiency and outstanding antibacterial properties. Hence, this holds significant potential for wastewater treatment applications.
The self-assembly of a dehydrophenylalanine containing dipeptide (see figure), yielding highly ordered nanotubular structures, is discussed. tubes are longer and thinner than previously reported peptide-based tubular structures; they stable to boiling-water temperatures, different pH conditions, nonspecific protease (Proteinase K). Supporting information for this article available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c1774_s.pdf or from author. Please note:...
Abrin and agglutinin-I from the seeds of Abrus precatorius are type II ribosome-inactivating proteins that inhibit protein synthesis in eukaryotic cells. The two toxins share a high degree sequence similarity; however, is weaker its activity. We compared kinetics inhibition by abrin different cell lines found approximately 200-2000-fold higher concentration needed for same inhibition. Like abrin, also induced apoptosis cells triggering intrinsic mitochondrial pathway, although at...
Adenine deaminase (ADE) catalyzes the conversion of adenine to hypoxanthine and ammonia. The enzyme isolated from Escherichia coli using standard expression conditions was low for deamination (k(cat) = 2.0 s(-1); k(cat)/K(m) 2.5 × 10(3) M(-1) s(-1)). However, when iron sequestered with a metal chelator growth medium supplemented Mn(2+) prior induction, purified substantially more active k(cat) values 200 s(-1) 5 10(5) s(-1), respectively. apoenzyme prepared reconstituted Fe(2+), Zn(2+), or...
Surface and interface engineering play a crucial role in enhancing the CO2 methanation performance of heterogeneous catalysts. In this study, we present NiO-TiO2 nanoparticles modified with oxygen vacancy-rich Fe3O4 clusters, significantly improving performance. The as-prepared catalyst (referred to as NiO@Fe3O4) achieves an impressive CH4 selectivity 91.2% methane production yield 6400.50 μmol/g at 573 K, approximately 83% increase compared unmodified NiO (3154.2 μmol/g). results physical...
Heavy metal pollution is a formidable global environmental concern, with far-reaching consequences for ecosystems and grave health risks to humans wildlife. This study investigated the potential of extremophilic Bacillus Sp: strains, namely halotolerans, as bioresources addressing heavy contamination through bioremediation. These species exhibited remarkable resistance biodegradation capabilities toward toxic metals rigorous lab-scale fermentation experiments. Within 24–48 h, strains...
The arid and semi-arid regions of Rajasthan are one the most extreme biomes India, possessing diverse microbial communities that exhibit immense biotechnological potential for industries. Herein, we sampled study sites from Thar Desert, Rajasthan, India subjected them to chemical, physical metagenomics analysis. diversity was studied using V3-V4 amplicon sequencing 16S rRNA gene by Illumina MiSeq. Our metagenomic analyses revealed consist mainly Proteobacteria (19-31%) followed unclassified...
The current investigation involves the green synthesis of copper nanoparticles (CuNPs) from an aqueous plant extract Moringa oleifera Lam by two methods: (I) time-based approach and (II) heat treatment solution. Prepared CuNPs were characterised via Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy transmission EM. study also reveals potential bioactivity prepared CuNPs. In vitro anti-microbial efficiency was estimated against bacterial fungal strains...
Abstract Adenine deaminase (ADE) from the amidohydrolase superfamily (AHS) of enzymes catalyzes conversion adenine to hypoxanthine and ammonia. Enzyme isolated Escherichia coli was largely inactive toward deamination adenine. Molecular weight determinations by mass spectrometry provided evidence that multiple histidine methionine residues were oxygenated. When iron sequestered with a metal chelator growth medium supplemented Mn 2+ before induction, post‐translational modifications...
Microorganisms have the capability to survive in all extremity's environments.The most preferred range of environmental conditions for microorganisms are temperature (20 -40 o C), pH (nearly neutral), pressure (1atm), adequate amount oxygen, water supply, nutrients and salts concentration.But there a few organisms which extremely harsh where normal life fails flourish these known as "Extremophiles".In order differentiate different forms microorganism is still optimal organism grows they...
To enhance the efficiency of painless targeted nanotherapies, integrating optical imaging capabilities into nanoplatforms is gaining momentum. Our study presents a cost-effective synthesis MoS2 nanoflower (MNF) and Indocyanine green (ICG) composites (MNF-ICG) using physical method based on van der Waals interactions. MNF, prepared via hydrothermal method, underwent characterization through UV-vis, FTIR, fluorescence spectroscopy, while FESEM XRD techniques were employed to analyse morphology...
Abstract This study reports the instantaneous synthesis of stable silver nanoparticles (AgNPs) at room temperature using a digallate (DG) derivative linked through hydrophilic oxyethylene spacer. The DG was synthesized standard ester coupling reaction and employed for production AgNPs. Digallate acted as very strong reducing stabilizing agent it reduced Ag ions in an aqueous media into (DG‐AgNPs) instantaneously temperature. DG‐AgNPs were characterized by UV/Vis, XPS, XRD, HR‐TEM, SEM, AFM,...
Additional Supporting Information may be found in the online version of this article. Please note: The publisher is not responsible for content or functionality any supporting information supplied by authors. Any queries (other than missing content) should directed to corresponding author
A vital method for diagnosing diseases, particularly in the detection of cancer, is antibody-antigen binding, prostate cancer second most common among men. Prostate typically diagnosed through specific antigen testing. Here, we synthesized a nanoplatform with gold functionalized molybdenum disulphide (MoS2) nanospheres, which can be useful modification working electrode electrochemical sensor detection. It based on identification biomarkers. For functionalization MoS2 nanospheres (Au)...