Xiaonan Chen

ORCID: 0000-0003-0680-546X
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About
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Research Areas
  • Cardiac Ischemia and Reperfusion
  • Diet and metabolism studies
  • Mitochondrial Function and Pathology

Shanghai Ninth People's Hospital
2022

Shanghai Jiao Tong University
2022

Background Heart failure with preserved ejection fraction (HFpEF) accounts for 50% of patients heart failure. Clinically, HFpEF prevalence shows age and gender biases. Although the majority are elderly, there is an emergence young HFpEF. A better understanding underlying pathogenic mechanism urgently needed. Here, we aimed to determine role aging in pathogenesis Methods Results dietary regimen (high‐fat diet + Nω‐Nitro‐L‐arginine methyl ester hydrochloride) was used induce wild type...

10.1161/jaha.121.024582 article EN cc-by-nc-nd Journal of the American Heart Association 2022-06-03
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