Geraniol presents many pharmacological properties including antifungal and antibacterial activity. The objective of this study was to conduct a review the literature concerning in vitro antimicrobial activity, anti-biofilm action, association studies with drugs geraniol. based on search from 2007 2019, databases Lilacs, Scielo, Science Direct, PubMed. results 21 articles 8were selected where most studied genera were Candida Staphylococcus. Broth microdilution methods frequently used...

Staphylococcus aureus is able to rapidly develop mechanisms of resistance various drugs and form strong biofilms, which makes it necessary new antibacterial drugs. The essential oil Melaleuca alternifolia used as an antibacterial, a property believed be mainly due the presence terpinen-4-ol. Based on this, objective this study was evaluate antibiofilm potential terpinen-4-ol against S. aureus. Minimal Inhibitory Bactericidal Concentrations (MIC MBC) were determined, effect its combination...

The increase in Staphylococcus aureus resistance to conventional antibacterials and persistent infections related biofilms, as well the low availability of new antibacterial drugs, has made development therapeutic alternatives necessary. Medicinal plants are one main sources bioactive molecules myrtenol is a natural product with several biological activities, although its antimicrobial activity little explored. Based on this, objective this study was evaluate against S. aureus, determining...

Introduction: Laboratory diagnosis related to clinical microbiology is highly complex, due subjectivity when interpreting the results. Among bacterial pathogens, those linked Staphylococcus genus are relevant from a and epidemiological point of view. Aim: To review literature relative main laboratory methods used for isolation identification microorganisms Staphylococcus. Methodology: The study was based on search between 2000 2020, in BVS, PubMed, Scielo, ScienceDirect CAPES Periodical...

Introduction: Type 1 diabetes mellitus (T1DM) is an autoimmune disease that requires continuous insulin therapy to improve patient survival. Objective: To evaluate the use of and related practices by T1DM patients in Cuité, Paraíba. Methodology: This cross-sectional, descriptive, quantitative study included 30 receiving Cuité/PB. Results: Most participants were male (56.7%), over 70 years old (33.4%), had low education (66.7%), income 1–3 minimum wages (86.7%). It was observed 83.3% reported...

Introduction: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, primarily affecting the lungs but capable of other structures and organs such as kidneys, meninges, bones, among others. This infection typically has a greater impact on immunocompromised individuals those with congenital infection. Despite importance epidemiological surveillance TB, there need for research this topic in pregnant women. Objective: Therefore, study aimed to outline profile women...

A dissecação anatômica em cadáveres humanos é uma prática fundamental no ensino da anatomia, proporcionando a visualização tridimensional das estruturas do corpo e o desenvolvimento de habilidades clínicas. Apesar dos avanços tecnológicos uso modelos anatômicos virtuais, permanece um método eficaz ao promover experiência consolidação conhecimento. Assim, presente estudo teve como objetivo relatar criação aplicação curso humanos, entre os meses abril maio 2024, universidade pública Estado...

Vulvovaginal candidiasis is one of the most common fungal infections in women, at some point their lives affecting approximately 75% this population. It primarily caused by fungus Candida albicans and can be triggered many factors, such as antibiotic use, diabetes, pregnancy, use hormonal contraceptives. The current large increase mycotic C. frequent therapeutic failure conventional antifungals, when added to development microorganism resistance has led need for antifungal studies on...

This study reports a social action carried out on National Health Day at municipal landfill in the state ofCeará, focusing democratization of comprehensive health and community care. The work, qualitative anddescriptive nature, exposes reality recyclable material collectors, historically marginalized group that facesunhealthy working conditions health, environmental, socio-economic vulnerabilities. action, promoted byvolunteers, included services such as blood pressure measurement, glucose...

The genus Candida is one of the main causes otomycosis. growing index fungal strains resistant to antifungals makes necessary search for new agents and α-pinene a phytoconstituent present in plants with remarkable antimicrobial activity, which becomes an interesting object study. Thus, objective this research was evaluate antifungal activity against species isolated from otomycosis, determining Minimum Inhibitory Fungicide Concentrations, micromorphological analysis verifying effects...

The enantiomers (R)-(+)-β-citronellol and (S)-(−)-β-citronellol are present in many medicinal plants, but little is understood about their bioactivity against Candida yeasts. This study aimed to evaluate the behavior of positive negative β-citronellol on strains albicans C. tropicalis involved candidemia. minimum inhibitory concentration (MIC) fungicide (MFC) were determined. evaluation growth kinetics, mechanism action, association studies with Amphotericin B (AB) using checkerboard method...

Introdução: Disfunção Temporomandibular (DTM) é o termo para designar um quadro de desorganização neuromuscular identificada pela presença cefaleias crônicas, sons na articulação temporomandibular, restrições dos movimentos mandibulares, hiperestesia e dor nos músculos da mastigação, cabeça do pescoço. Objetivo: realizar uma revisão literatura sobre a DTM. Material Método: foi feita seleção artigos científicos partir das bases dados LILACS SCIELO utilizando os descritores “Articulação...

This work describes the synthesis of spiro 1,3,4‐thiadiazolines from isatin‐β‐thiosemicarbazone acetylation, using microwave irradiation as a source heating reaction medium. N ‐substituted isatin derivatives were used substrates to obtain thiosemicarbazones by adding thiosemicarbazide ketone carbonyl. The final synthetic step was with acetic anhydride under get compounds. Reaction times ranged 6 18 minutes resulting in yields up 90%. Biological assays have shown promising antibacterial and...

Klebsiella pneumoniae causes a wide range of community and nosocomial infections. The high capacity this pathogen to acquire resistance drugs makes it necessary develop therapeutic alternatives, discovering new antibacterial molecules. Acetamides are molecules that have several biological activities. However, there no reports on the activity 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide. Based this, study aimed investigate in vitro molecule K. pneumoniae, evaluating whether presence chloro...

Onychomycosis is the most common disease affecting nail unit and accounts for at least 50% of all diseases. In addition, Candida albicans responsible approximately 70% onychomycoses caused by yeasts. This study investigated antifungal effect (R) (S)-citronellal enantiomers, as well its predictive mechanism action on C. from voriconazole-resistant onychomycoses. For this purpose, in vitro broth microdilution molecular docking techniques were applied a complementary manner to mechanisms...

The objective of the study was to develop and characterize gel based on Aloe vera for Manoel Casado de Almeida Pharmacy School. research done at Education Health Center off Federal University Campina Grande, located in city Cuité (PB). For quality control, chemical physical tests were carried out as determine pH, apparent density, viscosity, spreadability centrifugation test. demonstrated acceptable physicochemical characteristics exhibiting pH 5, bulk density 0.1018 (± 0.0008), viscosity...

The aim of this study was to determine the minimum inhibitory concentration carvacrol and evaluate antifungal activity when combinated with fluconazole, ketoconazole or amphotericin B against non-albicans Candida species. MICs were determined using microdilution method, combination conducted checkerboard method. MIC ranged between 128 512 μg/mL. greatest displayed ketoconazole. Conversely, fluconazole lowest activity. Amphotericin showed ranging from 0.5 2 best combinations observed...

<p><strong>Introduction</strong>: bacterial infections are a public health problem. Besides, the emergence of strains resistant to antimicrobials has<br />contributed search for new alternatives, such terpenes with antimicrobial potential. <strong>Objectives</strong>: objective this<br />study was determine possible interaction isolated monoterpenes (-)-Carveol, Geraniol, Citronellol, α-terpineol, R-(-) Carvone,<br />(-)-Menthol, Linalool,...

<p class="ECS-Texto"><span>O <em>Staphylococcus aureus</em> é um coco Gram-positivo encontrado em pele e mucosas de seres humanos. Em alimentos, pode produzir toxinas termo-estáveis capazes causar intoxicação estafilocócica. O presente estudo teve como objetivo fazer uma revisão bibliográfica acerca da contaminação alimentos pela bactéria <em>S. aureus,</em> ressaltando fatores que propiciam o seu desenvolvimento riscos atrelados a essa contaminação. Houve...

The present study aimed to elucidate the epidemiological profile of tuberculosis patients in Natal-RN between years 2010 and 2018. This was an epidemiological, retrospective documentary study, which recovery secondary data occurred from “Departamento de Informática do Sistema Único Saúde (DATASUS)” Brazil. following variables were studied: year notification, gender, age, schooling, area residence, ethnicity factors that facilitate onset tuberculosis. Statistical association performed using...

As dermatofitoses são infecções superficiais que caracterizam-se pelo acometimento de pele, e unhas, apresentando fungos do gênero Microsporum como importantes causadores dessas afecções. Assim, o presente estudo teve objetivo realizar uma revisão literatura sobre Microsporum, destacando-se as possíveis espécies desse podem causar, assim como, características epidemiológicas, patogênicas, imunológicas, diagnóstico tratamento farmacológico atualmente empregado. M.canis M.gypseum tem se...