A5040236545- Helicobacter pylori-related gastroenterology studies
- Inflammatory Bowel Disease
- IL-33, ST2, and ILC Pathways
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Eosinophilic Esophagitis
- Neuroendocrine regulation and behavior
- Genomics, phytochemicals, and oxidative stress
- Tannin, Tannase and Anticancer Activities
- Cytokine Signaling Pathways and Interactions
- Sirtuins and Resveratrol in Medicine
- Histone Deacetylase Inhibitors Research
- Phytochemicals and Antioxidant Activities
- Tea Polyphenols and Effects
- Bioactive Compounds and Antitumor Agents
- Ubiquitin and proteasome pathways
- Curcumin's Biomedical Applications
- CRISPR and Genetic Engineering
- Nigella sativa pharmacological applications
- Colorectal and Anal Carcinomas
- RNA Interference and Gene Delivery
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Essential Oils and Antimicrobial Activity
- Gastrointestinal Tumor Research and Treatment
Shahrekord University of Medical Sciences
2016-2024
Center for Digestive and Liver Diseases
2024
Massachusetts General Hospital
2020-2022
Harvard University
2020-2022
Weill Cornell Medicine
2020
Cornell University
2020
Context Experiencing early-life adversity plays a key role in the development of mood disorders adulthood. adversities during early life period negatively affects brain development. Sex steroids such as progesterone affect structure and functions subsequently behaviour.Objective We assess antidepressant-like effect mouse model maternal separation (MS) stress, focussing on its anti-neuroinflammatory antioxidative effects.Materials methods NMRI mice were treated with (10, 50, 100 mg/kg, i.p.,...
Background and objectives: With regard to their ease of harvest common developmental origin, dental pulp stem cells (DPSCs) may act as a favorable source in generation nerves. Moreover; cellular migration differentiation well survival, self-renewal, proliferation neuroprogenitor species require the presence central nervous system (CNS) mitogens including EGF bFGF. Accordingly, possibility induction neuronal DPSCs by bFGF was evaluated present study.Materials methods: were treated with 20...
Background: Ulcerative colitis (UC) is a chronic inflammatory disorder of the large intestine histologically characterized by indistinct sustained responses. Genetical susceptibility and environmental factors' effects play roles in disease occurrence it can be life threatening if remains untreated. It seems that intensification responses this condition not restricted to specific cell line T lymphocytes. Our aim was determine number helper 9 (Th9) cells inflamed colonic biopsies UC patients....
Abstract Background Experiencing early-life stress plays an important role in the pathophysiology of anxiety disorders. Ferulic acid is a phenolic compound found some plants which has several pharmacological properties. N-methyl-D-aspartate (NMDA) receptors are involved mood In this study we aimed to assess anxiolytic-like effect ferulic mouse model maternal separation (MS) by focusing on possible involvement NMDA receptors. Methods Mice were treated with (5 and 40 mg/kg) alone combination...
Fra-1 (fosl1) belongs to the activator protein1 (AP-1) family inducing IL-11 expression in oxidative stress condition. plays a pivotal role protecting epithelial barriers integrity. In this study, we investigated gene inflamed mucosa of patients with ulcerative colitis (UC) as well its relation expression. We enrolled 20 and healthy controls definite UC based on clinical criteria. non-inflamed colonic biopsies was determined by real-time polymerase chain reaction (RT-PCR). The protein...
Medicinal plants have long been studied due to their anticancer effects and use of them is commonly increased as a complementary alternative medicine (CAM therapies) among patients with cancer. In this study, Alhagi maurorum (A.m) Amygdalus haussknechtii (A.h) extracts were evaluated for on inhibiting the growth 4T1 breast cancer cells. Based MTT assay results, IC50s A.m A.h 57 µg/ml 85 µg/ml, respectively. Then cell migration, gene expression, degree apoptosis after 48 hours in each treated...
Colorectal cancer is common in Iran. However our knowledge about survival of rectal province low. The aim this study to evaluate question.Patients with documented pathology adenocarcinoma the rectum and rectosigmoid junction referred center from September 2004 2012 were enrolled study. Metastatic recurrent patients excluded. A questionnaire including clinicopathologic parameters, quality sequence treatment modalities was filled for each patient. Patients treated a combination surgery,...
One of the most important causes nosocomial infections is Staphylococcus aureus. The aim this study was to determine frequency these genes and rate expression during nasal colonization among personnel Kashani Hajar hospitals.In Analytical-descriptive study, 240 swab specimens were collected from different departments hospitals in Shahr-e-kord. Nasal cultured 110 strains isolated. Based on results, carriers aureus identified. clfA, clfB, fnbA fnbB 36.3%, 86.3%, 7.2% 43.6% respectively. It...
Abstract Degeneration and apoptotic death of the photoreceptor cell‐layer retina are a major cause irreversible blindness in development era. The stem cell replacement therapy is one strategies for retinal repairing. In addition, exogenous signals critically contribute to direction lineage decisions that causes fate‐restricted progenitors from progeny culture. It has been found epidermal growth factor (EGF), taurine, retinoic acid (RA) initially act instructive as well lineage‐restricted way...