The objective of this study is to describe the quality life (QoL) in cancer patients with solid tumors and at different chemotherapy (CT) cycles.A total 200 were included. With some modification, European Organization for Research Treatment Cancer QoL Questionnaire (EORTC QLQ-C30) was used measure student patients.There no correlation between variables such as age, sex, marital status, duration disease, economic conditions, occupational function. Furthermore, found patients' educational...

Diagnosis of glioblastoma multiform (GBM) with MRI lacks molecular information and requires a biopsy for pathologic confirmation. The EGFRvIII, is constitutively active mutant the EGF receptor, identified in high percentage brain cancers associated increased invasiveness resistance, making it good target to improve imaging diagnosis. present study shows that conjugation near-infrared quantum dot (Qd800) an anti-EGFRvIII single domain antibody, made variable region extra cysteine...

Gold nanoparticles with suitable properties are supreme therapeutic agents and provide effective signal enhancement in photodynamic therapy (PDT).

Objective: To determine the radioprotective effects of Silymarin in adult male Sprague-Dawley rats irradiated with γ-rays.Methods: The present experimental study was performed Tehran University Medical Sciences, Tehran, Iran from December 2009 to March 2010.The on 40 rats, which were randomly and equally divided into four groups: 1) control group: neither received nor γ-rays; 2) γ-irradiation testis region exposed 2Gy 3) & γ-irradiation: 100 mg/kg 24hrs before exposure 4) 200 γ-rays.After...

Patients with recurrent cervical carcinoma within a previously irradiated area respond poorly to chemotherapy. We have treated these patients simultaneous cisplatin and hyperthermia (CDDP + HT) investigated response, toxicity, palliative effect survival.Between 1992 2005 47 received CDDP HT. Response was evaluated by gynaecologic examination CT-scan. The Common Toxicity Criteria (CTC) were used for evaluation of toxicity effect. Kaplan-Meier method estimate survival, Cox regression analysis...

Introduction: The growing interest and participation in multi-institutional trials involving deep hyperthermia treatment is an important step towards the further consolidation of as oncological modality. However, differences clinical procedures application also raises questions how to compare reported temperatures data obtained by different institutes. In this study our recent developed approach, RHyThM (Rotterdam Hyperthermia Thermal Modulator), has been used for thermal analysis...

Treatment reproducibility is important to guarantee reproducible treatment-outcome, a low-complication rate and efficient treatment procedures. This study evaluated the performance of loco-regional deep hyperthermia with four BSD-2000 configurations during 1990–2005 using direct available parameters, i.e., temperature power. Primary cervical cancer patients (n = 444) were all treated within Sigma-60. Patients grouped in three weight-groups: <61 kg, 61–70 >70 kg. Different power indices...

Purpose: To characterize the basic performance of Sigma-60-Ellipse applicator.Materials and methods: The E-field distributions were measured using Schottky diode sheets in a cylindrical phantom (diameter 26 cm, length 50 cm), filled with saline-water (2 g NaCl/L). was positioned symmetrically applicator. stability SAR distribution assessed as function power frequency. Furthermore, accuracy target steering evaluated at various frequencies. Finally, characteristics compared those Sigma-60...

Currently ROS is known as the cause of many diseases and damage to cells tissues. Many studies have shown that related such cancer, cardiovascular, diabetic nephropathy even processes aging infertility. The past two decades reveal low controlled values in physiological process cell are secondary; while their essential for normal activity cell. Studies show most cells, amounts produced by NADPH oxidase family enzymes. These enzymes present plasma membrane where they increase production...

Introduction Radiation protection is an important safety issue for radiographers and patients. The aim of this study was to assess the observance radiation regulations in radiology departments Kermanshah University Medical Sciences, Kermanshah, Iran. Materials Methods In total, 48 8 radiography rooms were evaluated three hospitals Additionally, 120 patients randomly selected present study. For data collection, a questionnaire on devices, radiographers, completed. Data analyzed, using...

One of the systems used by hyperthermia (HT) groups for heating tumours in pelvic region is BSD2000 system. Previous versions operate on a PDOS machine and majority currently installed BSD2000/3D are still running under PDOS. Availability formatted treatment data provided has some difficulties. To facilitate analysis generated programme, called RHyThM (Rotterdam Hyperthermia Thermal Modulator) been created. The purpose first to read check integrity validity each measurement time space as...

Purpose: To investigate whether one can replace the Sigma-60 with Sigma-Eye applicator (or vice versa) during a deep hyperthermia treatment series without loss in quality of treatment.

Increasing use of cell-phone is one the most important risk factors for population health. We designed an experimental study aimed at evaluating effects radiofrequency (RF) waves exposure on fertilization in mice. Two hundred male and female NMRI-mice were used. One males divided five groups (n = 20) as control exposed groups. Those irradiated with RF "Standby-mode" 1, 5 10 h daily named II, III IV; respectively. Group V "Active-mode" hour daily. After 30 days irradiation, 50 females kept 24...

One of the leading causes death is brain tumors. Accurate tumor classification leads to appropriate decision making and providing most efficient treatment patients. This study aims optimize MR images accuracy using optimal threshold, PCA training Adaptive Neuro Fuzzy Inference System (ANFIS) with different repetitions.The procedure used in this consists five steps: (1) T1, T2 weighted collection, (2) separation threshold levels, (3) feature extraction, (4) presence absence reduction applying...

Recently, multidetector computed tomography (MDCT) has been introduced into clinical practice. MDCT become the noninvasive diagnostic test of choice for detailed evaluation biliary obstruction.the main objective present study was to evaluate value compared invasive procedures detecting obstruction causes.Since February 2009 until May 2011 fifty patients based on clinical, laboratory or ultrasonographic findings, were evaluated by Multidetector-row tomography. The causes obstruction, which...

The aim of this work was to present a theoretical analysis how phantom dimensions and tissue heterogeneities in interstitial brachytherapy affect on dose distributions.This carried out using Gafchromic film measurement Monte Carlo simulation for 192 Ir source.Results show that treatment planning systems (TPS) which consider the patient geometry as homogeneous medium, lead underestimation up 8.2% lung an overestimation 9% bone.These values depend thickness distance from source.Thus, TPSs...

After observing rather severe acute neurotoxicity in a few patients following deep hyperthermia treatment for pelvic tumour, we evaluated the incidence of all treated with pelvis between June 1990 and April 2004.Hyperthermia registrations hospital charts 736 were reviewed. Differences subgroups by 2 x exact tests.Grade or 3 occurred 2.3% patients, grade 0.7%. The duration symptoms was longer than months 6 (0.8%). Neurological examination 5 showed that most commonly involved structures are...

Traumatic spinal cord injury (TSCI) is a condition with suffering of neural structures from acute trauma short-term or permanent sensory and motor problems. This study was conducted the aim determining prevalence TSCI in Tehran emphasis on demographic characteristics patients to evaluate effect computed tomography (CT) fracture type severity grade among patients. In cross-sectional study, all (N = 520) who referred main center Tehran, Iran, 2013 2014 were selected. Radiography CT scan...

Introduction: Tissue type assignment, i.e. differentiation tumour from normal tissue, is a procedure for interstitial thermometry. In our department, thermometry in patients with the lower pelvis usually restricted to intra-luminal tracks. It unknown whether discrimination between and tissue relevant deep regional hyperthermia thermal dosimetry using only contact adjacent This study has analysed acquired temperature data order answer this question.Patients methods: Seventy-five locally...