One of the most common challenges in brain MRI scans is to perform different sequences depending on type and properties tissues. In this paper, we propose a generative method translate T2-Weighted (T2W) Magnetic Resonance Imaging (MRI) volume from T2-weight-Fluid-attenuated-Inversion-Recovery (FLAIR) vice versa using Generative Adversarial Networks (GAN). To evaluate proposed method, novel evaluation schema for synthetic approaches based radiomic features. For purpose, consider 510...

Introduction Radiotherapy treatment plans traditionally rely on physical indices like Dose-volume histograms and spatial dose distributions. While these metrics assess delivery, they lack consideration for the biological effects tumors healthy tissues. To address this, radiobiological models tumor control probability (TCP) Normal tissue complications (NTCP) are increasingly incorporated to evaluate efficacy potential complications. This study aimed predictive power of TCP in breast cancer...

Grid therapy recently has been picking momentum due to favorable outcomes in bulky tumors. This is being termed as Spatially Fractionated Radiation Therapy (SFRT) and lattice therapy. SFRT can be performed with specially designed blocks made brass or cerrobend repeated holes using multi-leaf collimators where dosimetry uncertain. The dosimetric challenge grid the mystery behind lower percentage depth dose (PDD) fields. knowledge about beam quality, indexed by TPR

The diagnosis accuracy of computed tomography (CT) systems and the reliability calculated Hounsfield Units (HUs) are critical in tumor detection cancer patients' treatment planning. This study evaluated effects scan parameters (Kilovoltage peak or kVp, milli-Ampere-second mAS reconstruction kernels algorithms, field view, slice thickness) on image quality, HUs, dose planning system (TPS).A quality verification phantom was scanned several times by a 16-slice Siemens CT scanner. DOSIsoft ISO...

Background: In the past, GRID therapy was used as a treatment modality for of bulky and deeply seated tumors with orthovoltage beams. Now introduction megavoltage beams to radiotherapy, some radiotherapy institutes use photons palliative tumors. Since can be barrier weakening photoneutrons produced in head medical linear accelerators (LINAC), well secondary source producing photoneutrons, therefore, terms radiation protection, it is important evaluate effect on photoneutron dose patients....

Laminated barriers incorporating metal sheets provide effective protection for space-restricted radiotherapy centers. This study aimed to assess photoneutron contamination in smaller vaults protected by different compositions of multilayer during simulated pelvic with 18 MV photon beams. Monte Carlo Simulations LINAC (Varian 2100 C/D) and Medical Internal Radiation Dose (MIRD) phantom were used within reconstructed combinations sheet borated polyethylene (BPE) radiotherapy. The findings...

Abstract Purpose: This study compares tumor control probability (TCP) and normal tissue complication (NTCP) across different hypo-fractionated (HypoRT) conventional breast radiotherapy regimens using radiobiological models. Materials methods: Computed tomography data from 30 patients with left breast-conserving surgery were used to evaluate three HypoRT (39 Gy 41·6 in 13 fractions, 40 15 fractions) a regimen (50 25 fractions). Dose-volume histograms (DVHs) extracted for calculations...

Background: The objective of this study was to design and construct a CO2 incubator with nonmetallic walls investigate the viability cells microwave irradiance inside incubator. Methods: Because conventional incubators are made metal, causes scattering, reflection, absorption electromagnetic waves. We decided build wall examine under radiation. Incubator were using polyvinyl chloride Plexiglas then temperature, pressure, humidity sensors placed in it. Atmel® ATmega1284, low-power CMOS 8-bit...

Nowadays, in most radiotherapy departments, the commercial treatment planning systems (TPS) used to calculate dose distributions needs be verified; therefore, quick, easy‐to‐use, and low‐cost distribution algorithms are desirable test verify performance of TPS. In this paper, we put forth an analytical method phantom scatter contribution depth on central axis based equivalent square concept. Then, was generalized profiles at any for several field shapes — regular or irregular fields—under...

One of the leading causes death is brain tumors. Accurate tumor classification leads to appropriate decision making and providing most efficient treatment patients. This study aims optimize MR images accuracy using optimal threshold, PCA training Adaptive Neuro Fuzzy Inference System (ANFIS) with different repetitions.The procedure used in this consists five steps: (1) T1, T2 weighted collection, (2) separation threshold levels, (3) feature extraction, (4) presence absence reduction applying...

Abstract Spatially fractionated radiation therapy (SFRT) refers to the delivery of a single large dose within target volume in heterogeneous pattern using either custom GRID block, multileaf collimators, and virtual methods such as helical tomotherapy or synchrotron-based microbeams. The potential impact this technique on regression bulky deep-seated tumors that do not respond well conventional radiotherapy has been remarkable. To date, number patients have treated SFRT techniques. However,...

Neutron contamination in radiation therapy is of concern treatment with high-energy photons (> 10 MV). With the development new radiotherapy modalities such as spatially fractionated grid (SFGRT) or briefly radiotherapy, more studies are required to evaluate risks associated neutron contamination. In 15 MV SFGRT, high-Z materials lead and cerrobend used block on tray linear accelerator (linac) which can probably increase photoneutron production. On other hand, high-dose fractions (10-20 Gy)...

Trauma patients often suffer from multiple injuries and require undergoing various radiography which is referred to as multifield radiographic examinations. Protective measures may be ignored for these examinations due stressful emergency situations or patients' conditions. This study was conducted evaluate the scattered doses received by pelvis during different common with an emphasis on field size adjustment.

Introduction: One of the important input factors in commissioning radiotherapy treatment planning systems is phantom scatter factor (Sp) which requires same collimator opening for all radiation fields.In this study, we have proposed an analytical method to overcome issue.Methods: The measurements were performed using Siemens Primus Plus with photon energy 6 MV field sizes from 5×5cm 2 40×40cm .Phantom was measured through division total output (Scp), and (Sc). Results:The mean percent...

Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because its capability tumor characterization.To assess based on histopathological findings transrectal ultrasound (TRUS)-guided biopsy as reference, an increase in signal intensity prostatic lesions comparison with normal background tissue b-value diffusion-weighted images could be sign malignancy.Fifty-three consecutive patients...

Nowadays, the use of radiopharmaceuticals in medicine is unavoidable. Depending on distribution radiopharmaceutical cells, nucleus absorbed dose changes by variations their geometry size. Therefore, this study aims to investigate S-value variation size using Geant4 toolkit.Two spherical cells with a variety have been considered as cancerous cell. Monoenergetic electrons ranging from 5 300 keV are distributed uniformly. The for four target-source components (including Nucleus←Cytoplasm,...

Introduction: Pituitary neuroendocrine tumours (PitNETs) are common accounting for 10 to 25 % of all intracranial tumours. This project describes the feasibility developing a novel membrane-based biomarker that could be used fluorescent guided surgery. The aim was catalogue differential expression membrane proteins between non-functional PitNETs and pituitary glands. Methodology: Ten gland tissue specimens were obtained from National Institute Health (NIH) NeuroBio- Bank twenty Northwestern...