Théophile Grébert

ORCID: 0000-0003-0699-1194
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About
Contact & Profiles
Research Areas
  • Microbial Community Ecology and Physiology
  • Photosynthetic Processes and Mechanisms
  • Algal biology and biofuel production
  • Wildlife Ecology and Conservation
  • Protist diversity and phylogeny
  • Genomics and Phylogenetic Studies
  • Wildlife-Road Interactions and Conservation
  • Marine and coastal ecosystems
  • Ecology and Vegetation Dynamics Studies
  • Cancer Research and Treatments
  • Plant Virus Research Studies
  • Biomedical Text Mining and Ontologies
  • Biochemical and Molecular Research
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Advanced biosensing and bioanalysis techniques
  • Enzyme Structure and Function
  • CRISPR and Genetic Engineering
  • Biocrusts and Microbial Ecology
  • Land Use and Ecosystem Services
  • Bacteriophages and microbial interactions
  • Advanced Text Analysis Techniques
  • Pancreatic function and diabetes
  • RNA and protein synthesis mechanisms
  • Topic Modeling
  • Botany and Plant Ecology Studies

Station Biologique de Roscoff
2018-2024

Adaptation et Diversité en Milieu Marin
2019-2024

Sorbonne Université
2018-2024

Centre National de la Recherche Scientifique
2018-2023

Institut Pasteur
2023

Université Paris Cité
2023

Laboratoire de Biométrie et Biologie Evolutive
2021

Université Claude Bernard Lyon 1
2021

Université Clermont Auvergne
2020

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020

Abstract Genetic tools derived from the Cas9 RNA-guided nuclease are providing essential capabilities to study and engineer bacteria. While importance of off-target effects was noted early in Cas9’s application mammalian cells, cleavage by bacterial genomes is easily avoided due their smaller size. Despite this, several studies have reported experimental setups which expression toxic, even when using catalytic dead variant (dCas9). Specifically, dCas9 shown be toxic complex with guide RNAs...

10.1093/nar/gkad170 article EN cc-by-nc Nucleic Acids Research 2023-03-17

Marine Synechococcus cyanobacteria are major contributors to global oceanic primary production and exhibit a unique diversity of photosynthetic pigments, allowing them exploit wide range light niches. However, the relationship between pigment content niche partitioning has remained largely undetermined due lack single-genetic marker resolving all types (PTs). Here, we developed employed robust method based on three distinct genes ( cpcBA , mpeBA mpeW ) estimate relative abundance known PTs...

10.1073/pnas.1717069115 article EN Proceedings of the National Academy of Sciences 2018-02-12

Synechococcus cyanobacteria are ubiquitous and abundant in the marine environment contribute to an estimated 16% of ocean net primary productivity. Their light-harvesting complexes, called phycobilisomes (PBS), composed a conserved allophycocyanin core, from which radiates six eight rods with variable phycobiliprotein chromophore content. This variability allows cells optimally exploit wide variety spectral niches existing ecosystems. Seven distinct pigment types or subtypes have been...

10.1093/gbe/evac035 article EN cc-by-nc Genome Biology and Evolution 2022-03-08

Numbering in excess of 10 million per milliliter water, it is now undisputed that aquatic viruses are one the major factors shaping ecology and evolution Earth's microbial world. Nonetheless, environmental viral diversity roles remain poorly understood. Here we report first thorough characterization a virus (designated TsV) infects coastal marine microalga Tetraselmis striata. Unlike previously known microalgae-infecting viruses, TsV small (60 nm) DNA virus, with 31 kb genome. From range...

10.3390/v7072806 article EN cc-by Viruses 2015-07-17

Abstract All characterized members of the ubiquitous genus Acaryochloris share unique property containing large amounts chlorophyll (Chl) d , a pigment exhibiting red absorption maximum strongly shifted towards infrared compared to Chl . is major in these organisms and notably bound antenna proteins structurally similar those Prochloron Prochlorothrix Prochlorococcus only three cyanobacteria known so far contain mono- or divinyl-Chl b as pigments lack phycobilisomes. Here, we describe...

10.1038/s41598-018-27542-7 article EN cc-by Scientific Reports 2018-06-08

Significance Of all cyanobacteria on Earth, marine Synechococcus are those displaying the greatest pigment diversity. The most sophisticated type is cells able to reversibly modify their color by a phenomenon called IV chromatic acclimation or CA4. Two genetically distinct CA4 types (CA4-A and CA4-B) have evolved in different lineages. Together, they represent almost half of oceanic areas equally abundant but occupy complementary ecological niches. While molecular mechanism CA4-A has...

10.1073/pnas.2019715118 article EN Proceedings of the National Academy of Sciences 2021-02-24

A bstract The Theory of Island Biogeography (TIB) promoted the idea that species richness within sites depends on site connectivity, i.e. its connection with surrounding potential sources immigrants. TIB has been extended to a wide array fragmented ecosystems, beyond archipelagoes, surfing analogy between habitat patches and islands patch-matrix framework. However, patch connectivity often little contributes explaining in empirical studies. Before interpreting this trend as questioning broad...

10.1101/640995 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2019-05-17

Abstract Synechococcus picocyanobacteria are ubiquitous and abundant photosynthetic organisms in the marine environment contribute for an estimated 16% of ocean net primary productivity. Their light-harvesting complexes, called phycobilisomes (PBS), composed a conserved allophycocyanin core from which radiates six to eight rods with variable phycobiliprotein chromophore content. This variability allows optimally exploit wide variety spectral niches existing ecosystems. Seven distinct pigment...

10.1101/2021.06.21.449213 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-06-21
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