A5048098697- Mosquito-borne diseases and control
- Virology and Viral Diseases
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Rabies epidemiology and control
- Vaccine Coverage and Hesitancy
- Viral Infections and Immunology Research
- Venomous Animal Envenomation and Studies
- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Autoimmune and Inflammatory Disorders Research
- Medical and Biological Ozone Research
- Identification and Quantification in Food
- Fish Biology and Ecology Studies
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- Ichthyology and Marine Biology
- Marine Invertebrate Physiology and Ecology
- Biosimilars and Bioanalytical Methods
- Vibrio bacteria research studies
- Infectious Encephalopathies and Encephalitis
- Leptospirosis research and findings
National Institute for Research in Reproductive Health
2020-2024
Indian Council of Medical Research
2011-2024
Department of Health Research
2021-2024
Community Link
2021
Topiwala National Medical College & BYL Nair Charitable Hospital
2021
Government of Maharashtra
2019-2021
Government of India
2019-2021
Regional Medical Research Centre
2011-2020
Regional Medical Research Centre
2011-2016
ICAR - Central Island Agricultural Research Institute
2016
Chikungunya virus (CHIKV) has caused large outbreaks worldwide in recent years. Acute-phase CHIKV infection been reported to cause mild severe febrile illness, and some patients, this may be followed by long-lasting polyarthritis. The mainstay of treatment includes nonsteroidal anti-inflammatory drugs other disease-modifying agents, the use which is based on assumption an immunological interference mechanism pathogenesis. present study designed generate preliminary evidence test hypothesis....
Vaccination and passive antibody therapies are critical for controlling infectious diseases. Passive administration has limitations, including the necessity purification multiple injections efficacy. is associated with a lag phase before generation of immunity. Novel approaches reported here utilize benefits both methods rapid effective immunity.A novel antibody-based prophylaxis/therapy entailing electroporation-mediated delivery synthetic DNA plasmids encoding biologically active...
In Brief Rates of severe coronavirus disease 2019 (COVID-19), intensive care unit admission, and maternal mortality increased among pregnant postpartum women admitted for COVID-19 in the second wave compared with first India.
India has remarkably the highest number of snakebite cases contributing to nearly 50% global deaths. Despite this fact, there is limited knowledge and awareness regarding management practices for in Indian population. The study aimed explore knowledge, awareness, perception snakes snakebites, first aid, treatment amongst community frontline health workers a tribal block Dahanu, Maharashtra, India.A cross-sectional was carried out from June 2016 October 2018 Dahanu Block, Maharashtra....
Background Snakebite envenoming (SBE) is an acute, life-threatening emergency in tropical and subtropical countries. It occupational hazard a major socioeconomic determinant. Limited awareness, superstitions, lack of trained health providers, poor utilization anti-venom results high mortality morbidity. India the snakebite capital world. Yet, information on knowledge, perceptions about limited. Data capacity building systems its potential impact lacking. Recommended by National Task Force...
Biology and pathogenesis of chikungunya virus (CHIKV) are not clearly established. Host factors play an important role in determining the progression severity disease. Polymorphisms promoter region CD209 gene (rs735239, rs4804803, rs2287886) OAS1 (rs1131454 rs10774671), OAS2 (rs15895 rs1732778), OAS3 (rs2285932 rs2072136) genes were investigated 100 patients with CHIKV infection 101 healthy controls to find out association these polymorphisms infection. To evaluate OAS presence or absence...
Rotavirus is the most common cause of severe diarrhoea worldwide, affecting over 125 million young children every year in developing countries. The present study a part ongoing childhood diarrhoeal surveillance to determine strain diversity rotaviruses prevalent Andaman and Nicobar Islands. From October 2010 February 2012, 296 stool samples from (age group 6–60 months) with gastroenteritis were obtained different referral hospitals/primary health centres community A total 47 found positive...
Summary A sudden upsurge of fever cases with joint pain was observed in the outpatient department, C ommunity H ealth entre, R angat during J uly– ugust 2010 M iddle ndaman, I ndia. The aetiological agent responsible for outbreak identified as chikungunya virus ( CHIKV ), by using RT‐PCR and IgM ELISA . study investigated association polymorphisms human leucocyte antigen class II genes susceptibility or protection against One hundred one patients clinical features suggestive infection 104...
SUMMARY Prior to 2009 dengue fever had not been reported in the Andaman and Nicobar archipelago. In 2009, a few patients with fever-like illness were reported, some of whom tested positive for antibodies. 2010, 516 suspected cases including haemorrhagic (DHF) shock syndrome (DSS); 80 (15·5%) DENV RNA was detected five PCR-based typing showed that three these belonged serotype 1 two 2. This confirmed by sequence typing. Two clones virus, one belonging other 2 appeared be circulating Andaman....
Fingerprick blood spotted onto filter paper offers an alternative to venous for use in population-based surveillance because it is comparatively inexpensive, acceptable, and easy manage the field. Prior studies have shown excellent agreement immunoglobulin G (IgG) antibody detection from dried spots (DBS) samples. However, much of this evidence high-income settings or laboratories where samples were unlikely be exposed extreme temperatures humidity, factors known degrade DBS. We report...
Chikungunya virus (CHIKV) is an Alphavirus belonging to the family Togaviridae. In 2006, CHIKV infection struck Andaman and Nicobar archipelago, with attack rate of 60%. There were more than 10 cases acute flaccid paralysis simulating Guillian Barre Syndrome. The majority patients presented severe joint pain. cause for such explosive nature outbreak increased morbidity was not known. isolation attempted succeeded from nine subjects presenting clinical symptoms fever. cDNA all isolates...
Background: Chikungunya (CHIKV) disease is a serious emerging mosquito-transmitted viral infection responsible for epidemic outbreaks. Currently, no licensed vaccines or therapies are available against this virus, resulting in significant global spread with concurrent population morbidity. Methods & Materials: This study describes novel immune-based intervention that utilizes vivo deliver of synthetic DNA plasmids encoding monoclonal antibody (mAb) targeting the CHIKV envelope protein....
In alignment with the Measles and Rubella (MR) Strategic Elimination plan, India conducted a mass measles rubella vaccination campaign across country between 2017 2020 to provide dose of MR containing vaccine all children aged 9 months 15 years. We estimated coverage in five districts assessed awareness factors associated during better understand reasons for not receiving dose.