Nagarajan Muruganandam

ORCID: 0000-0003-0430-221X
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About
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Research Areas
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Viral Infections and Immunology Research
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory viral infections research
  • Ichthyology and Marine Biology
  • Identification and Quantification in Food
  • Cervical Cancer and HPV Research
  • Malaria Research and Control
  • Fish Biology and Ecology Studies
  • Herpesvirus Infections and Treatments
  • Virus-based gene therapy research
  • Reproductive tract infections research
  • GABA and Rice Research
  • Animal Disease Management and Epidemiology
  • Viral Infections and Outbreaks Research
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Hepatitis Viruses Studies and Epidemiology
  • Hepatitis B Virus Studies
  • Retinal and Optic Conditions
  • Oral Health Pathology and Treatment
  • Influenza Virus Research Studies
  • Agricultural Economics and Practices
  • Head and Neck Cancer Studies

Regional Medical Research Centre
2015-2025

Indian Council of Medical Research
2012-2025

Regional Medical Research Centre
2014-2025

Indian Agricultural Research Institute
2024-2025

Ministry of Health and Family Welfare
2024

Tamil Nadu Agricultural University
1995-2024

Meenakshi Academy of Higher Education and Research
2024

Regional Medical Research Centre
2013-2023

Jawaharlal Institute of Post Graduate Medical Education and Research
2023

Chaudhary Charan Singh Haryana Agricultural University
2023

This longitudinal follow-up study of 203 patients with serologically confirmed chikungunya (CHIK) virus infection describes the clinical features CHIK fever during first and tenth months illness. During acute stage presents a wide array symptoms. The foremost chronic symptoms at end month were rheumatism (75%) fatigue (30%). symptoms/signs observed joint pain/swelling (46%), (13%) neuritis (6%). cure rate 9 was 51%. Among who had pain, 36% (34/94) met American College Rheumatology criteria...

10.1016/j.trstmh.2010.01.011 article EN Transactions of the Royal Society of Tropical Medicine and Hygiene 2010-02-20

Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus indigenous to tropical Africa and Asia. Acute illness characterized by fever, arthralgias, conjunctivitis, rash, sometimes arthritis. Relatively little known about the antigenic targets for immunity, no licensed vaccines or therapeutics are currently available pathogen. While Aedes aegypti mosquito its primary vector, recent evidence suggests that other carriers can transmit CHIKV thus raising concerns spread outside of...

10.1371/journal.pntd.0000928 article EN cc-by PLoS neglected tropical diseases 2011-01-11

Chikungunya virus (CHIKV) has caused large outbreaks worldwide in recent years. Acute-phase CHIKV infection been reported to cause mild severe febrile illness, and some patients, this may be followed by long-lasting polyarthritis. The mainstay of treatment includes nonsteroidal anti-inflammatory drugs other disease-modifying agents, the use which is based on assumption an immunological interference mechanism pathogenesis. present study designed generate preliminary evidence test hypothesis....

10.1089/vim.2010.0123 article EN Viral Immunology 2011-08-01

Abstract Background Human papillomavirus (HPV) is associated with cervical cancer and dysplasia worldwide. Data on HPV prevalence in a region important because it serves as predictor of the likelihood population that particular acquiring cancer. Moreover, availability effective vaccines, public health system must be aware preponderance to implement vaccine. The present study was designed understand factors among women South Andaman Island. Methods A cross-sectional conducted married...

10.1186/s12905-024-02967-7 article EN cc-by BMC Women s Health 2024-02-23

Human papillomavirus (HPV) is a viral infection, and its acquisition persistence are significantly influenced by the vaginal microbiota. Understanding comparing microbiome of HPV infected women in Andaman Nicobar Islands crucial. The study involved collecting swabs extracting DNA using QIAamp Minikit. was then subjected to PCR amplification confirm infection. illumina NovaSeq 6000 platform utilized perform sequencing utilizing 2 x 250 paired end chemistry. Taxonomic analysis performed...

10.3389/fcimb.2024.1486166 article EN cc-by Frontiers in Cellular and Infection Microbiology 2025-01-15

Background: WHO data on increased CVDs in India is estimated to be one of the greatest any country world. The Nicobarese tribes are indigenous tribes, habited difficult reach, rural, and remote Islands Bay Bengal. Methods: A community-based cross-sectional study was conducted among 365 Nicobar Tribes using HEARTS risk prediction charts distribution determinants NCD factors predict 10-year CVD risk. Results: 66.8% were obese, 24.4% smokers. Smokeless tobacco use prevalent 74.8 62.5% reported...

10.18203/2394-6040.ijcmph20250314 article EN International Journal of Community Medicine and Public Health 2025-01-31

The goal of the study is to understand drillship structural behavior under extremely hazardous hurricane conditions, as well variables influencing their strength and stability. In present study, two cases are considered: a analyzed sea states severe storm conditions using data from Gulf Mexico, ice loads acting impact loads. Studies show that experienced instability caused by excessive roll pitch response motion. critical design shear stress longitudinal bending moment predominantly affected...

10.33175/mtr.2025.275456 article EN Maritime Technology and Research 2025-02-07

Abstract In the changing climatic scenario, application of proteomics for accelerated identification elite genes is an important way to speed up development lines. Seeds, reservoir protein expression in most aspects plant development, are attractive platform identifying unique/novel proteins. There has been no report on seed proteome basmati rice ( Oryza sativa L.). This study presents, first time, superior Indian varieties Pusa Basmati 1121 and 1718, which genetic resources breeding....

10.1002/csc2.70028 article EN Crop Science 2025-03-01

The outbreak of chikungunya fever that surfaced in India during late 2005 has affected more than 1.56 million people, spread to 17 states/union territories, and is still ongoing. Many these areas are dengue- leptospirosis-endemic settings. We carried out a cross-sectional survey one such chikungunya-affected location Dakshina Kannada District Karnataka State estimate the magnitude epidemic proportion virus (CHIKV) infections remained clinically inapparent. seropositivity for CHIKV infection...

10.4269/ajtmh.2010.09-0433 article EN American Journal of Tropical Medicine and Hygiene 2010-10-01

Chikungunya virus (CHIKV) is an important emerging mosquito-borne alphavirus, indigenous to tropical Africa and Asia. It can cause epidemic fever acute illness characterized by arthralgias. The cycle of this infection similar dengue urban yellow viral infections. generation efficient vaccine against CHIKV necessary prevent and/or control the disease manifestations infection. In report, we studied immune response a CHIKV-envelope DNA (pEnv) role nonstructural gene 2 (nsP2) as adjuvant for...

10.1089/vim.2012.0061 article EN Viral Immunology 2013-02-01

Biology and pathogenesis of chikungunya virus (CHIKV) are not clearly established. Host factors play an important role in determining the progression severity disease. Polymorphisms promoter region CD209 gene (rs735239, rs4804803, rs2287886) OAS1 (rs1131454 rs10774671), OAS2 (rs15895 rs1732778), OAS3 (rs2285932 rs2072136) genes were investigated 100 patients with CHIKV infection 101 healthy controls to find out association these polymorphisms infection. To evaluate OAS presence or absence...

10.1089/dna.2015.2819 article EN DNA and Cell Biology 2015-09-23

Human Papillomavirus (HPV) causes various types of cancer in both men and women. Woman with HPV infection has a risk developing invasive cervical cancer. Globally, 16 18 were predominant. This study aims to find the distribution South Andaman.A cross-sectional was conducted among women Andaman, where scrapes collected after collecting written informed consent. Detection genotypes carried out by using PCR assay. Further, sequencing analysis performed MEGA11 identify this territory.Of these...

10.3390/diagnostics13172765 article EN cc-by Diagnostics 2023-08-25

Rotavirus is the most common cause of severe diarrhoea worldwide, affecting over 125 million young children every year in developing countries. The present study a part ongoing childhood diarrhoeal surveillance to determine strain diversity rotaviruses prevalent Andaman and Nicobar Islands. From October 2010 February 2012, 296 stool samples from (age group 6–60 months) with gastroenteritis were obtained different referral hospitals/primary health centres community A total 47 found positive...

10.1159/000342219 article EN Intervirology 2012-12-28

The present study was undertaken to understand the distribution and antimicrobial susceptibility patterns of uropathogens in remote islands India. Patients' demographical data, urine culture results, resistance rates were analyzed multidrug resistant isolates characterized. Significant bacteriuria found 16 (17.7%, 95% confidence interval [CI] 8.47–23.53%) samples, which includes Escherichia coli 9 (56.3%); Klebsiella pneumoniae 3 (18.8%); Enterobacter sp. 2 (12.5%) Proteus mirabilis (12.5%)....

10.1089/mdr.2013.0070 article EN Microbial Drug Resistance 2013-07-17

Summary A sudden upsurge of fever cases with joint pain was observed in the outpatient department, C ommunity H ealth entre, R angat during J uly– ugust 2010 M iddle ndaman, I ndia. The aetiological agent responsible for outbreak identified as chikungunya virus ( CHIKV ), by using RT‐PCR and IgM ELISA . study investigated association polymorphisms human leucocyte antigen class II genes susceptibility or protection against One hundred one patients clinical features suggestive infection 104...

10.1111/imm.12128 article EN Immunology 2013-05-25

SUMMARY Prior to 2009 dengue fever had not been reported in the Andaman and Nicobar archipelago. In 2009, a few patients with fever-like illness were reported, some of whom tested positive for antibodies. 2010, 516 suspected cases including haemorrhagic (DHF) shock syndrome (DSS); 80 (15·5%) DENV RNA was detected five PCR-based typing showed that three these belonged serotype 1 two 2. This confirmed by sequence typing. Two clones virus, one belonging other 2 appeared be circulating Andaman....

10.1017/s0950268811002500 article EN Epidemiology and Infection 2011-12-08
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