A5085235957- T-cell and B-cell Immunology
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Reproductive System and Pregnancy
- Virus-based gene therapy research
- Immune Cell Function and Interaction
Deutsche Knochenmarkspenderdatei
2018-2020
The killer-cell immunoglobulin-like receptor (KIR) genes regulate natural killer cell activity, influencing predisposition to immune mediated disease, and affecting hematopoietic stem transplantation outcome. Owing the complexity of KIR locus, with extensive gene copy number variation allelic diversity, high-resolution characterization has so far been applied only relatively small cohorts. Here, we present a comprehensive high-throughput genotyping approach based on next generation...
Molluscum contagiosum virus (MCV) is a common cause of benign skin lesions in young children and currently the only endemic human poxvirus. Following infection primary keratinocytes epidermis, MCV induces proliferation infected cells this results production wart-like growths. Full productive observed after differentiate. During prolonged replication cycle must avoid elimination by host immune system. We therefore sought to investigate function two major histocompatibility complex...