A5101828936- Multiple Sclerosis Research Studies
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Breast Lesions and Carcinomas
- Bone and Joint Diseases
- Neuroscience and Neuropharmacology Research
- Systemic Lupus Erythematosus Research
- Functional Brain Connectivity Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Alzheimer's disease research and treatments
- Breast Cancer Treatment Studies
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Traditional Chinese Medicine Studies
- Cerebral Venous Sinus Thrombosis
- Mental Health Research Topics
- Migraine and Headache Studies
- Sperm and Testicular Function
- Education and Work Dynamics
- Hair Growth and Disorders
- Rheumatoid Arthritis Research and Therapies
- Cognitive Science and Education Research
- Proteoglycans and glycosaminoglycans research
- Environmental Monitoring and Data Management
- Scoliosis diagnosis and treatment
The Affiliated Yongchuan Hospital of Chongqing Medical University
2018-2025
Chongqing Medical University
2018-2025
Xuzhou Medical College
2023
Harbin Medical University
2020
First Affiliated Hospital of Harbin Medical University
2020
Capital Medical University
2016
Beijing Tongren Hospital
2016
Wuhan University of Science and Technology
2016
Hainan Normal University
2014
The First Affiliated Hospital, Sun Yat-sen University
2013
Objectives To investigate whether patients with neuromyelitis optica spectrum disorder (NMOSD) have tract-specific alterations in the white matter (WM) and correlations between cognitive impairment. Materials Methods In total, 40 NMOSD 20 healthy controls (HCs) who underwent diffusion tensor imaging (DTI) scan neuropsychological scale assessments were enrolled. Automated fiber-tract quantification (AFQ) was applied to identify quantify 100 equally spaced nodes of 18 specific WM fiber tracts...
Abstract The aim of this study was to investigate the mechanisms underlying demyelination and remyelination with 7.0 T multiparameter magnetic resonance imaging (MRI) in an alternative cuprizone (CPZ) mouse model multiple sclerosis (MS). Sixty mice were divided into six groups (n = 10, each), these imaged MRI treated CPZ administration schedule. 2 -weighted (T WI), susceptibility-weighted (SWI), diffusion tensor (DTI) used compare splenium corpus callosum (sCC) among groups. Prussian blue...
Background Sex-related effects have been observed in relapsing-remitting multiple sclerosis (RRMS), but their impact on functional networks remains unclear. Objective To investigate the sex-related differences connectivity strength and time variability within large-scale RRMS. Methods This is a multi-center retrospective study. A total of 208 RRMS patients (135 females; 37.55 ± 11.47 years old) 228 healthy controls (123 36.94 12.17 were included. All participants underwent clinical MRI...
Abstract Aims To explore large‐scale brain network alterations and examine their clinical neuropsychological relevance in patients with anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis. Methods Twenty‐four anti‐NMDAR encephalitis 26 matched healthy controls (HCs) were enrolled our study. Based on the multimodal MRI dataset, individual morphological, structural, functional networks constructed compared between two groups at multiple levels. The associations clinical/neuropsychological...
To evaluate the microstructural damage in heterogeneity of different white matter areas relapsing-remitting multiple sclerosis (RRMS) patients by using diffusion kurtosis imaging (DKI) and its correlation with clinical cognitive status.Kurtosis fractional anisotropy (KFA), (FA), mean (MK), diffusivity (MD) T1-hypointense lesions (T1Ls), pure T2-hyperintense (pure-T2Ls), normal-appearing (NAWM), healthy controls (WM HCs) were measured 48 RRMS 26 sex- age-matched HCs. All participants assessed...
Objectives . To comprehensively and quantitatively assess the process of lung liquid clearance using ultrasound score. This study is to evaluate whole healthy lungs neonates during first 24 h. Methods Lung was performed in with no respiratory symptoms within 3 h after birth, scans were then repeated at 6 hours hours, respectively. The entire chest wall divided into 12 regions. scores anterior, posterior, upper, lower regions sum all calculated according pattern each region examined. Results...
We describe a modified canaloplasty technique and report the short-term efficacy for primary open-angle glaucoma (POAG) patients with disruption of Schlemm canal (SC) wall resulting from prior surgery.This was single-surgeon prospective cohort study. POAG scheduled were included divided into 2 groups: group1 without history surgery group failed disrupted SC. The status SC determined by gonioscopy ultrasound biomicroscopy. Standard procedures performed in 1. A used 2. Primary outcome measures...
Objectives: To implement a machine learning model using radiomic features extracted from quantitative susceptibility mapping (QSM) in discriminating multiple sclerosis (MS) neuromyelitis optica spectrum disorder (NMOSD). Materials and Methods: Forty-seven patients with MS (mean age = 40.00 ± 13.72 years) 36 NMOSD 42.14 12.34 who underwent enhanced gradient-echo T2*-weighted angiography (ESWAN) sequence 3.0-T MRI were included between April 2017 October 2019. QSM images reconstructed ESWAN,...
This study aimed to investigate iron deposition and thickness signal changes in optic radiation (OR) by enhanced T2*-weighted angiography imaging (ESWAN) patients with relapsing-remitting multiple sclerosis (RRMS) unilateral bilateral lesions or no lesions.Fifty-one RRMS (42 a disease duration [DD] ≥ 2 years [group Mor], nine DD < Les]) 51 healthy controls (group Con) underwent conventional magnetic resonance (MRI) ESWAN at 3.0 T. The mean phase value (MPV) of the OR was measured on image,...
Objective To investigate the differences in short-, middle- and long-range connections between patients with relapse-remitting multiple sclerosis (RRMS) neuromyelitis optica spectrum disorder (NMOSD), their correlation brain tissue volume, structural functional network parameters. Methods A total of 51 RRMS, 42 NMOSD 56 health controls (HC) were recruited. Of these 25 RRMS (median: 1.37 years) 20 1.25 also studied at follow-up. The whole-brain fiber connection was divided into three groups...