A5076900974- Vascular Tumors and Angiosarcomas
- Sarcoma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Chromatin Remodeling and Cancer
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Gestational Trophoblastic Disease Studies
- Cancer and Skin Lesions
- Ear and Head Tumors
- Genetic factors in colorectal cancer
- Testicular diseases and treatments
- Neuroblastoma Research and Treatments
- Endometrial and Cervical Cancer Treatments
- Bladder and Urothelial Cancer Treatments
- Cardiac tumors and thrombi
- Lymphoma Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Bone Tumor Diagnosis and Treatments
- Uterine Myomas and Treatments
- HER2/EGFR in Cancer Research
- Prenatal Screening and Diagnostics
Rajiv Gandhi Cancer Institute and Research Centre
2015-2025
Creative Commons
2023
Cancer Institute (WIA)
2018
Maharishi Markandeshwar University, Mullana
2012
Work-life balance is a critical aspect to enhance teacher effectiveness and satisfaction in the context of student learning. It has been proved time again that good quality work life results into wellness faculty also improved behaviour. The present study investigated work-life among Indian teachers serving different academic stream across universality colleges. emerged from outcome designation teachers, their nature appointment, which they are teaching, institution affect directly...
IntroductionFumarate hydratase (FH) deficient uterine leiomyomas account for only 0.4 % of all leiomyomas. They are characterized by some distinct histological features and may be associated with Hereditary leiomyomatosis renal cell carcinoma (HLRCC) syndrome.MethodsHerein we present a series five cases FH in patients mean age 30 years. All underwent myomectomy. Three these had an outside histopathologic diagnosis ranging from Smooth muscle tumor uncertain malignant potential (STUMP) to...
Primary classical Hodgkin lymphomas of the gastrointestinal tract are rare lymphoproliferative neoplasms as against other well established mucosa-associated lymphoid tissue (MALT) lymphomas. The primary nature these cases is based on chest radiograph, computed axial tomography, positron emission peripheral blood and bone marrow biopsy examination. Here, we report a 79-year-old male patient, who presented to emergency department with complaints abdominal discomfort right side low grade fever....
Spindle epithelial tumor with thymus-like elements (SETTLE) is a rare malignant neoplasm of the thyroid gland which believed to arise from intrathyroidal thymic tissue. It predominantly affects young adults and children presenting mass variable duration rarely occurs in adults. has high overall survival tendency for delayed metastasis. SETTLE biphasic lobulated composed spindle shaped cells along glandular formations seen on histopathological examination. Despite its typical morphology it...
Eosinophilic solid and cystic renal cell carcinoma (ESCRCC) is an under-recognized, emerging new entity of sporadic neoplasms, with approximate incidence 0.2% tumors. A total 60 cases have been reported in the literature till date. ESCRCC are usually seen adult females, a low stage indolent behavior, rare recurrence or metastasis. They tumors variably sized cysts resembling eosinophilic RCC, showing characteristic positive immune-expression for PAX-8, CK20 (in ~80% cases) and/or Melan–A...
Pseudomyogenic hemangioendothelioma (PMH) is a rare tumor of vascular origin with intermediate malignant potential which commonly presents as subcutaneous and soft-tissue mass or without concurrent bone involvement. However, PMH presenting primary multifocal lesions rare. Histomorphologically, it mimicks other epithelioid tumors cytokeratin expression in can prompt an erroneous diagnosis metastatic carcinoma, especially elderly patient. Diligent histopathological examination judicious...
Giant cell tumor of bone (GCTB) is a benign neoplasm, which can sometimes be diagnostic challenge, especially in small biopsies, due to its histologic and malignant mimics. We evaluated the role H3.3 G34W immunohistochemistry (IHC) antibody diagnosing GCTB differentiating it from close A total 120 cases (80 40 mimics) were retrieved subjected IHC. Of 80 GCTB, 72 showed positive nuclear immunoexpression, while all mimics negative staining for Sensitivity specificity this mutation-specific...
Male breast cancers (MBCs) are uncommon and account for 1% of all cancers. Medical conditions that increase the estrogen to testosterone ratio implicated as risk factors. Morphologically similar, but MBCs have biological differences compared with female cancer (FBC).The present study was aimed examine immunophenotype MBC, subsequent molecular subtypes, their association clinicopathological features, prognosis.We analyzed features 42 cases classified them according classification using...
The ASCO/CAP guidelines for HER2 reporting in breast cancer published 2007 and were updated 2013 to assure that the right patient receives targeted therapy. have lowered threshold positivity criteria altered equivocal category both IHC FISH. This first study from India addresses impact of these various categories at a tertiary care centre. We compared trend 1 year before (Period A) after B) implementation guidelines. All cases post reclassified as per detect additional number been put into...
Human epidermal growth factor receptor 2 (HER-2) is an established prognostic and predictive biomarker for breast cancer. To ensure accuracy uniformity HER-2 testing, ASCO/CAP published guidelines in 2007 which were updated 2013 recently 2018. In this first study from Indian Oncology center, we evaluated the impact of 2018 guidelines. We found a substantial decrease equivocal IHC cases (P-value < .00001). On reclassification, total 5.6% positive categories (2013 guidelines) shifted to...
Hepatoid adenocarcinoma of lung is a rare entity, accounting for 5% all hepatoid adenocarcinoma. Distinguishing it from metastatic hepatocellular carcinoma essential, but occasionally can be very challenging, especially with concurrent liver mass. A judicious immunohistochemical panel warranted accurate diagnosis and subsequent preservation tissue molecular testing. There limited data on the mutational status, behavior management strategies this type We report largest series six cases citing...
Ewing sarcoma (ES) are malignant small round cell tumors (MSRCT) characterized by rearrangements of EWSR1 gene. Although gold standard for diagnosis is detection specific fusion genes molecular testing, these ancillary tests costly and only available in limited number settings. There a persuasive evidence reliability NKX2.2 immunohistochemistry (IHC) as surrogate marker gene rearrangement ES.The aim this study to correlate the immuno-expression with genetically confirmed ES cases also assess...
Lymphoepithelial carcinoma (LEC) of head and neck region predominantly arises in salivary gland, oral cavity, oropharynx, nasal paranasal sinuses, larynx; those arising from tongue are rare. Morphologically, it is a poorly differentiated squamous cell carcinoma, with early regional distant metastasis. Diagnosis LEC can sometimes be challenging especially small biopsy more so when seen at unusual location. Combination morphology immunohistochemistry (IHC) helps the diagnosis. Herein, we...
Epithelioid hemangioma of bone is a rare and locally aggressive vascular neoplasm associated with good prognosis. Because its worrisome histomorphologic features clinicoradiologic findings, at times multifocal presentation, they tend to simulate malignant tumors. We report series four cases epithelioid their clinicopathologic characteristics. All had adjacent soft tissue involvement two disease. Microscopically, all tumor in lobular configuration, composed endothelial cells the formation...
Epithelioid variant of angiomyolipoma (EAML) is a newly defined entity and close mimicker renal cell carcinoma.There growing body evidence to suggest its aggressive behavior in terms local recurrence, metastasis death.The treatment for this subset patients has posed challenges the experts.Chemotherapy plays little active role so molecular profiling identify genomic alterations amenable targeted therapies paved way.Recently, tyrosine kinase inhibitors mTOR have been utilised both adjuvant...