A5047562722- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- Advanced Memory and Neural Computing
- Photoreceptor and optogenetics research
- EEG and Brain-Computer Interfaces
Rice University
2020-2025
University of Houston
2022
Abstract Microinfarcts, the “invisible lesions”, are prevalent in aged and injured brains associated with cognitive impairments, yet their neurophysiological impact remains largely unknown. Using a multimodal chronic neural platform that combines functional microvasculature imaging spatially resolved recording, neurovascular effect of single microinfarct is investigated. Unlike larger strokes, microinfarcts induced only temporary suppression activity minimal cell death, recovery paralleling...
Significance: Electrophysiological recording and optical imaging are two prevalent neurotechnologies with complementary strengths, the combined application of which can significantly improve our capacity in deciphering neural circuits. Flexible electrode arrays support longitudinal same brain region, but their mechanical flexibility makes surgical preparation challenging. Here, we provide a step-by-step protocol by an ultraflexible nanoelectronic thread is co-implanted cranial window single...
Abstract Flexible neural electrodes improve the recording longevity and quality of individual neurons by promoting tissue-electrode integration. However, intracortical implantation flexible inevitably induces tissue damage. Understanding longitudinal vascular recovery following is critical for ever-growing applications in both healthy disordered brains. Aged animals are particular interest because they play a key role modeling neurological disorders, but their interface remains mostly...