Leila Suemi Harima Letaif
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Telemedicine and Telehealth Implementation
- Infection Control and Ventilation
- Disaster Response and Management
- Family and Patient Care in Intensive Care Units
- Infection Control in Healthcare
- Machine Learning in Healthcare
- Viral Infections and Outbreaks Research
- COVID-19 diagnosis using AI
- Health Systems, Economic Evaluations, Quality of Life
- Artificial Intelligence in Healthcare
- Multi-Criteria Decision Making
- Prostate Cancer Treatment and Research
- Mobile Health and mHealth Applications
- Hormonal and reproductive studies
- Health, Environment, Cognitive Aging
- Frailty in Older Adults
- Healthcare during COVID-19 Pandemic
- Dermatological and COVID-19 studies
- Healthcare Policy and Management
- Healthcare Regulation
- SARS-CoV-2 and COVID-19 Research
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2024
Universidade de São Paulo
2008-2023
The aim of this study was to determine whether Post-acute Sequelae SARS-CoV-2 Infection (PASC) are associated with physical inactivity in COVID-19 survivors. This is a cohort survivors discharged from tertiary hospital Sao Paulo, Brazil. Patients admitted as inpatients due laboratory-confirmed between March and August 2020 were consecutively invited for follow-up in-person visit 6 11 months after hospitalization. Ten symptoms PASC assessed using standardized scales. Physical activity by...
Abstract Background CoronaVac, a vaccine containing inactivated SARS-CoV-2, demonstrated efficacy of 50.39% 14 days or more after the 2nd dose. The objective this study is to report occurrence symptomatic COVID-19 in cohort HCW vaccinated with CoronaVac and estimate its effectiveness. Methods was given HCWs inHospital das Clinicas on 18-21 January, 2021 (epi week 3) (22,402 HCWs), 14-16 February, 7) (21,652 HCWs). Weekly cases were evaluated. Using period from 2020 epi 24 through 2 (before...
As of August 30, 2020, Brazil ranked second among countries with the highest number COVID-19 cases, city São Paulo as national epidemic epicenter. Local public healthcare institutions were challenged to respond a fast-growing hospital demand, reengineering care provision optimize clinical outcomes and minimize intra-hospital coronavirus infection. In this paper we describe how largest complex in Latin America faced unprecedented burden, managing severe cases while sustaining specialized...
The coronavirus disease 2019 pandemic increased global demand for personal protective equipment (PPE) and resulted in shortages. study evaluated the re-use of surgical masks respirators by analysing their performance safety before after reprocessing using following methods: oven, thermal drying, autoclave, hydrogen peroxide plasma vapour.In total, 45 69 were decontaminated. Visual integrity, air permeability, burst resistance, pressure differential particulate filtration efficiency new...
Coronavirus disease 2019 (COVID-19) is associated with high mortality among hospitalized patients and incurs costs. Severe acute respiratory syndrome coronavirus 2 infection can trigger both inflammatory thrombotic processes, these complications lead to a poorer prognosis. This study aimed evaluate the association temporal trends of D-dimer C-reactive protein (CRP) levels incidence venous thromboembolism (VTE), hospital mortality, costs inpatients COVID-19.Data were extracted from electronic...
Obesity is believed to be a risk factor for COVID-19 and unfavorable outcomes, although data on this remains better elucidated. To evaluate the impact of obesity endpoints patients hospitalized due SARS-CoV-2. This retrospective cohort study evaluated at tertiary hospital (Hospital das Clínicas da Faculdade de Medicina USP) from March December 2020. Only positive (real-time PCR or serology) were included. Data collected medical records included clinical demographic information, weight...
To evaluate the long-term outcomes and satisfaction of nonurgent patients who seek care in emergency department (ED) are diverted to primary health services (PHS).Data were collected from 264 ED a tertiary public university hospital São Paulo, Brazil. The patient definition was performed by Manchester triage system version II (MTS-II) associated medical interview service. Satisfaction levels evaluated telephone interviews. assessed within 30 days after visit.Based on MTS-II, 56.4 percent...
Abstract Background COVID-19 caused more than 622 thousand deaths in Brazil. The infection can be asymptomatic and cause mild symptoms, but it also evolve into a severe disease lead to death. It is difficult predict which patients will develop disease. There are, the literature, machine learning models capable of assisting diagnose predicting outcomes for several diseases, usually these require laboratory tests and/or imaging. Methods We conducted observational cohort study that evaluated...
We designed a cohort study to describe characteristics and outcomes of patients with coronavirus disease (COVID-19) admitted the intensive care unit (ICU) in largest public hospital Sao Paulo, Brazil, as Latin America becomes epicenter pandemic.This is protocol for being conducted at an academic Brazil 300 adult ICU beds dedicated COVID-19 patients. will include suspected or confirmed during period. The main outcome survival 28 days. Data be collected prospectively retrospectively by trained...
Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration enhance quality and efficiency. Methods At FMUSP-HC academic health system, we implemented innovative flow management routines for collecting, organizing analyzing demographic data, COVID-related data biological materials from over 4,500 patients with confirmed SARS-CoV-2 hospitalized 2020 2022. This strategy was mainly planned in...
As a consequence of the SARS-CoV-2 pandemic, social contact among people has undergone significant changes. To slow spread virus, distancing measures, such as isolation and maintenance distance between individuals, which includes changing manner in greet each other, are place, demonstrating responsible health practices. The lack physical with other human beings is major challenge during this highly contagious pandemic. protect vulnerable people, hospitals have discontinued all visitations; [...]
This study assessed the disinfection using 70% ethanol; H2O2-quaternary ammonium salt mixture; 0.1% sodium hypochlorite and autoclaving of four 3D-printed face shields with different designs, visor materials; thickness (0.5-0.75 mm). We also investigated their clinical suitability by applying a questionnaire to health workers (HW) who used them. Each type was done 40 times on each mask without physical damage. In contrast, led appreciable
Abstract Importance Strength and muscle mass are predictors of relevant clinical outcomes in critically ill patients, but hospitalized patients with COVID-19 remains to be determined. Objective To investigate whether strength or predictive hospital length stay (LOS) moderate severe COVID-19. Design Prospective observational study. Setting Clinical Hospital the School Medicine University Sao Paulo. Participants One hundred ninety-six were evaluated. Ten did not test positive for SARS-CoV-2...
Para planejar-se diante da emergência infecção por COVID-19 na China, que viria a se tornar uma pandemia com imensa demanda dos serviços de saúde, o Hospital das Clínicas Faculdade Medicina Universidade São Paulo (HCFMUSP) ativou precocemente seu plano desastres e, como resposta, posteriormente isolou maior instituto, 900 leitos, para ficasse exclusivamente dedicado ao atendimento pacientes COVID-19. Esse processo envolveu transferência e (unidades internação emergência) os outros...
RACIONAL: O processo patológico mais discutido na gênese da cirrose hepática é a fibrose progressiva, porém alterações vasculatura do órgão têm sido apontadas como elementos fundamentais fisiopatologia doença e de suas complicações, hipertensão portal, insuficiência carcinoma hepatocelular. OBJETIVO: Avaliar densidade microvascular em 35 casos necropsias pacientes com mediante pesquisa imunoistoquímica marcador endotelial CD34 fim comparar os informes obtidos semi-quantificação aqueles...
Optimal COVID-19 management is still undefined. In this complicated scenario, the construction of a computational model capable extracting information from electronic medical records, correlating signs, symptoms and prescriptions, could improve patient management/prognosis.