- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Colorectal and Anal Carcinomas
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Screening and Detection
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Intraperitoneal and Appendiceal Malignancies
- Genetic factors in colorectal cancer
- Gallbladder and Bile Duct Disorders
- COVID-19 and healthcare impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroendocrine Tumor Research Advances
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Stoma care and complications
- Radiomics and Machine Learning in Medical Imaging
- Clinical Nutrition and Gastroenterology
- Tracheal and airway disorders
- Diverticular Disease and Complications
Universidade de São Paulo
2016-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2025
Amrita Institute of Medical Sciences and Research Centre
2025
Amrita Vishwa Vidyapeetham
2025
Centro Universitário das Faculdades Metropolitanas Unidas
2025
Instituto do Câncer do Estado de São Paulo
2015-2024
Hospital Universitário da Universidade de São Paulo
2000-2024
Sociedade Brasileira de Oncologia Clínica
2024
Centro Brasileiro de Pesquisas Físicas
2023-2024
Pirogov Russian National Research Medical University
2024
Report overall long-term results of stage 0 rectal cancer following neoadjuvant chemoradiation and compare between operative nonoperative treatment.Two-hundred sixty-five patients with distal adenocarcinoma considered resectable were treated by (CRT) 5-FU, Leucovorin 5040 cGy. Patients incomplete clinical response referred to radical surgical resection. surgery resulting in p0 compared complete treatment. Statistical analysis was performed using chi2, Student t test Kaplan-Meier...
Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence of relaxations the lower sphincter and peristalsis along body. As result, patients typically present with dysphagia, regurgitation occasionally chest pain, pulmonary complication malnutrition. New diagnostic methodologies therapeutic techniques have been recently added to armamentarium for treating achalasia. With aim offer clinicians an up-to-date framework making informed decisions on management this...
Several studies have indicated that a restrictive erythrocyte transfusion strategy is as safe liberal one in critically ill patients, but there no clear evidence to support the superiority of any perioperative patients with cancer.In randomized, controlled, parallel-group, double-blind (patients and outcome assessors) trial intensive care unit tertiary oncology hospital, authors evaluated whether (transfusion when hemoglobin concentration <7 g/dl) was superior <9 for reducing mortality...
INTRODUCTION: The aim of this study was to evaluate the impact combined radiotherapy and chemotherapy (leucovorin 5-fluorouracil) on treatment potentially resectable low rectal cancer using following end points: 1) toxicity modality regimen; 2) clinical pathologic response rate local control; 3) downstaging tumor its influence number sphincter-saving operations; 4) disease-free interval, patterns relapse, overall survival. METHODS: From 1991 1996, 118 patients with cases histologically...
Colorectal carcinoma is considered the fourth leading cause of cancer deaths worldwide. Several microorganisms have been associated with carcinogenesis, including Enterococcus spp., Helicobacter pylori, enterotoxigenic Bacteroides fragilis, pathogenic E. coli strains and oral Fusobacterium. Here we qualitatively quantitatively evaluated presence intestinal in fecal microbiota colorectal patients healthy controls. Seventeen (between 49 70 years-old) visiting Cancer Institute Sao Paulo State...
Chemoradiotherapy has the potential to downsize and downstage tumors before surgery, decrease locoregional recurrence, induce a complete sterilization of tumor cells for middle low locally advanced rectal cancer. A watch-and-wait tactic been proposed patients with clinical response.The purpose this study was verify our ability identify response in cancer based on radiologic criteria.This prospective study.The conducted at single institution, setting randomized trial.Consecutive stage T3...
<h3>Importance</h3> Ninety-day mortality rates after esophagectomy are an indicator of the quality surgical oncologic management. Accurate risk prediction based on large data sets may aid patients and surgeons in making informed decisions. <h3>Objective</h3> To develop validate a model death within 90 days for cancer using International Esodata Study Group (IESG) database, largest existing prospective, multicenter cohort reporting standardized postoperative outcomes. <h3>Design, Setting,...
Cancer of the oesophagus has great diversity in geographical distribution and incidence. The rate oesophageal cancer been increasing some areas reasons for this are not clear. This review outlines fascinating epidemiological aspects risk factor squamous cell carcinoma oesophagus. While Western world effects alcohol tobacco substantial preconditions, worldwide other factors, such as diet, nutritional deficiencies, environmental exposure infectious agents (especially papillomavirus fungi),...
BACKGROUND The ability to predict biologic behavior and treatment responsiveness would be a valuable asset in the multimodality approach esophageal carcinoma. authors examined whether alterations of p53 gene correlate with clinicopathologic parameters, response preoperative chemotherapy/radiotherapy, outcome patients METHODS Histopathologic/genetic analysis was performed on formalin fixed, paraffin embedded tissues. Tissue sections were stained immunohistochemically for protein followed by...
ABSTRACT Background: Despite recent advances in diagnosis and treatment, esophageal cancer still has high mortality. Prognostic factors associated with patient disease itself are multiple poorly explored. Aim: Assess prognostic variables patients. Methods: Retrospective review of all patients an oncology referral center. They were divided according to histological (444 squamous cell carcinoma 105 adenocarcinoma), their demographic, pathological clinical characteristics analyzed compared...
Background and Objectives Gastric cancer (GC) has recently been categorized in molecular subtypes, which include Epstein‐Barr (EBV)‐positive microsatellite instability (MSI) tumors. This distinction may provide prognostic information identifies therapeutic targets. The aim of this study was to evaluate EBV, MSI, PD‐L1 immunoexpression GC its relationship with clinicopathological characteristics patient's prognosis. Methods We evaluated 287 patients who underwent D2‐gastrectomy through...
Surgery remains the cornerstone treatment modality for gastric cancer, fifth most common type of tumor in Brazil. The aim this study was to analyze surgical outcomes patients with cancer who were referred a high-volume university hospital.We reviewed all consecutive underwent any procedure due from prospectively collected database. Clinicopathological characteristics, and survival evaluated, emphasis on treated curative intent.From 2008 2017, 934 tumors procedures our center. Gastric...
Patients undergoing abdominal surgery for solid tumours frequently develop major postoperative complications, which negatively affect quality of life, costs care and survival. Few studies have identified the determinants perioperative complications in this group. We performed a prospective observational study including all patients (age > 18) cancer at single institution between June 2011 August 2013. emergency surgery, palliative procedures, or participating other were excluded. Primary...