A5101417731- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Workplace Health and Well-being
- Spondyloarthritis Studies and Treatments
- Musculoskeletal Disorders and Rehabilitation
- Sociology and Education Studies
- Psychology, Coaching, and Therapy
- Corporate Management and Leadership
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Health and Medical Studies
- Education Methods and Technologies
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Job Satisfaction and Organizational Behavior
- Medical Practices and Rehabilitation
- Innovation, Technology, and Society
- School Health and Nursing Education
- Employment and Welfare Studies
- Ethics and Social Impacts of AI
- Teacher Professional Development and Motivation
- Immunodeficiency and Autoimmune Disorders
- Inflammatory Myopathies and Dermatomyositis
- Lymphoma Diagnosis and Treatment
- Corporate Governance and Management
- Sarcoidosis and Beryllium Toxicity Research
Immanuel Krankenhaus
2016-2025
FHNW University of Applied Sciences and Arts
2011-2024
Deutsche Gesellschaft für Urologie
2020-2023
Weatherford College
2022
University of Oxford
2020
ETH Zurich
2017-2019
Kantonsschule Olten
2018
Medizinische Hochschule Hannover
2012-2017
Idorsia (Switzerland)
2017
CHI Health Immanuel
2006-2015
<h3>Objective</h3> To evaluate the Rheumatoid Arthritis Observation of Biologic Therapy (RABBIT) Risk Score for serious infections in patients with rheumatoid arthritis (RA). <h3>Methods</h3> The RABBIT was developed 2011 on a cohort RA enrolled German biologics register between 2001 and 2007. this score, we used data from after 1 January 2009. Expected numbers expected at least one infection per year were calculated by means compared observed evaluation sample. <h3>Results</h3> score an...
To report for the first time on efficacy and safety of anti-TNF therapy after 8 years follow-up in patients with active AS, analyse possible short-term predictors long-term clinical outcomes.In this open-label extension a randomized controlled trial, proportions initially included 69 AS were treated infliximab 5 mg/kg i.v./6 weeks years. The last was published All analyses based completers.Overall, 33 (48%) completed Their mean (s.d.) BASDAI [2.6 (1.9)], BASFI [3.3 (2.6)] BASMI [2.7 (2.4)]...
As the central strain dimension of burnout, emotional exhaustion is a popular indicator poor mental health in work and organizational psychology. Based on job demands-resources (JD-R) model, present article focuses antecedents processes leading to exhaustion. We hypothesized that sickness presenteeism (conceptualized as active problem-focused coping) would partially mediate relationship between characteristics (workload coworker support) Additionally, we examined potential interaction...
The growing threat of terrorism has increased the importance aviation security and work airport officers (screeners). Nonetheless, research yet to focus on emotional exhaustion job satisfaction as major determinants screeners' performance. present study bridges this gap by applying demands-resources (JD-R) model using work-family conflict (WFC) an intervening variable relationships between characteristics (workload supervisor support), exhaustion, in 1,127 screeners at a European airport....
Zusammenfassung Die Beurteilung von Patienten mit v. a. einer interstitiellen Lungenerkrankung (ILD) umfasst die klinischer, radiologischer und oft histopathologischer Daten. Da bislang noch keine dezidierten Empfehlungen für Evaluation bei Verdacht auf eine ILD in Deutschland existierten, war es Ziel dieses interdisziplinären Konsensusstatements, praktische Orientierungshilfe den klinischen Alltag Bezug interdisziplinäre Diagnostik der ILDs zu geben. Dazu gehören umfassende...
<h3>Objective</h3> To evaluate the safety and efficacy of tocilizumab in clinical practice patients with rheumatoid arthritis (RA) inadequate responses (IR) to disease-modifying antirheumatic drugs (DMARDs) or both DMARDs tumour necrosis factor α inhibitors (TNFis). <h3>Methods</h3> Patients—categorised as TNFi-naive, TNFi-previous (washout) TNFi-recent (no washout) —received open-label (8 mg/kg) every 4 weeks ± for 24 weeks. Adverse events (AEs) treatment discontinuations were monitored....
Objectives To investigate the impact of disease activity and treatment with disease-modifying antirheumatic drugs (DMARDs) on all-cause mortality in patients rheumatoid arthritis prevalent interstitial lung (RA-ILD). Methods Patients RA-ILD were selected from biologics register Rheumatoid Arthritis: Observation Biologic Therapy (RABBIT). Using time-varying Cox regression, association between clinical measures was investigated. The DMARDs analysed by (1) regression considering cumulative...
To evaluate the safety and feasibility of laparoscopic adrenalectomy (LA) performed in several German centres with different experience, as LA has become gold-standard approach for benign surgical adrenal disorders; however, solitary metastasis or primary cancer its precise role is uncertain.The data 363 patients who underwent a were prospectively collected 23 centres. All stratified into three groups according to their experience: group A (<10 LAs/year), B (10-20 LAs/year) C (>20 LAs/year)....
The aim of this study was to evaluate the safety and efficacy rituximab (RTX) in a large cohort patients with rheumatoid arthritis routine care, monitor changes daily practice since introduction RTX therapy. This multicentre, prospective, non-interventional conducted under conditions Germany. Efficacy evaluated using Disease Activity Score 28 joints (DAS28) Health Assessment Questionnaire-Disability Index (HAQ-DI). Safety assessed by recording adverse drug reactions (ADRs). Physician patient...
Abstract In the past, empirical research findings from psychosciences contributed to avoiding erroneous judgments and decisions in criminal proceedings. However, for some time now, developments have arisen that threaten reverse achievement at turn of millennium introduced a clear scientific orientation into sex offense This article highlights five retrograde uses three examples illustrate how these can interact and, particular, offer purported explanation lack memory experienced abuse....
The clinical course of fibrosing alveolitis (FA) in patients with systemic sclerosis (SSc) may vary considerably from stable condition for years to continuous fatal progression. This prospective study aimed at identifying the prognostic value bronchoalveolar lavage fluid (BALF) analysis FASSc.Seventy three consecutive SSc and signs pulmonary involvement were enrolled. Every patient underwent examination, lung function tests, computed tomography (CT), gallium scan, echocardiography, (BAL)....
Purpose The paper seeks to investigate into the shared services phenomenon in context of government reforms. It especially aims address emergence and shaping services. develop notion service centres (SSCs) networks (SSNs). Design/methodology/approach An interview‐ document analysis‐based multiple case study was conducted Germany. qualitative analysis covered two projects on local level. Findings Important preconditions for are identified, including cost pressure as motive, existence key...
The objective of this study was to use data from a noninterventional evaluate the effectiveness adalimumab in rheumatoid arthritis (RA) patients during routine clinical practice and explore potential impact patient disease characteristics response therapy. A total 2,625 RA with specified at baseline (prior initiating treatment) 12 months entered between April 2003 March 2009. We evaluated therapy conducted stepwise regression subgroup analyses factors influencing therapeutic response. During...