A5003723169- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health and Medical Studies
- Lymphoma Diagnosis and Treatment
- Musculoskeletal Disorders and Rehabilitation
- Immunodeficiency and Autoimmune Disorders
- Systemic Sclerosis and Related Diseases
- Osteoarthritis Treatment and Mechanisms
- Urticaria and Related Conditions
- Salivary Gland Disorders and Functions
- Biosimilars and Bioanalytical Methods
- Hepatitis C virus research
- Asthma and respiratory diseases
- Adolescent and Pediatric Healthcare
- Otitis Media and Relapsing Polychondritis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inflammatory Myopathies and Dermatomyositis
- Psoriasis: Treatment and Pathogenesis
- Oral Health Pathology and Treatment
- Child and Adolescent Health
- Tuberculosis Research and Epidemiology
- Pharmaceutical studies and practices
German Rheumatism Research Centre
2016-2025
Charité - Universitätsmedizin Berlin
2016-2025
Klinikum Stuttgart
2023
Olgahospital
2023
MRC Epidemiology Unit
2021
University of Birmingham
2016
Leibniz Association
2015
Kerckhoff Klinik
2007-2014
Justus-Liebig-Universität Gießen
2007-2014
German Society of Surgery
2013
Abstract Objective To introduce a new standardized ultrasound score based on 7 joints of the clinically dominant hand and foot (German US7 score) implemented in daily rheumatologic practice. Methods The included following foot: wrist, second third metacarpophalangeal proximal interphalangeal, fifth metatarsophalangeal joints. Synovitis synovial/tenosynovial vascularity were scored semiquantitatively (grade 0–3) by gray‐scale (GS) power Doppler (PD) ultrasound. Tenosynovitis erosions for...
Objective. To investigate the prevalence of comorbidities in a population-based cohort persons with rheumatoid arthritis (RA) compared to matched controls and examine their association patient-reported outcomes survey sample. Methods. Data 96,921 RA [International Classification Diseases, 10th ed (ICD-10) M05/M06] 484,605 age- sex-matched without German statutory health fund were studied regarding 26 selected (ICD-10). A self-reported questionnaire, comprising joint counts [(tender count...
To compare event and incidence rates of herpes zoster (HZ), also known as shingles, in patients with rheumatoid arthritis under treatment conventional synthetic (cs), targeted (ts) or biologic (b) disease-modifying antirheumatic drugs (DMARDs).Patients were prospectively enrolled from 2007 until October 2020. Reported HZ events assigned to ongoing treatments those terminated within 1 month prior the event. Exposure-adjusted (EAERs) calculated per 1000 patient years (py) adjusted HRs 95% CIs...
To estimate the effects of Janus kinase inhibitors (JAKi), tumour necrosis factor (TNFi), other biologic(b) or conventional synthetic(cs) disease-modifying antirheumatic drugs (DMARDs) on risk major adverse cardiovascular events (MACE) in patients with rheumatoid arthritis (RA).Cohort study analysing episodes DMARD-treatment initiated between January 2017 and April 2022 biologics register Rheumatoid Arthritis: Observation Biologic Therapy. Incidence rates (IRs) per 100 patient-years 95% CIs...
Objective To analyse work participation among patients with inflammatory rheumatic musculoskeletal diseases (iRMDs), namely rheumatoid arthritis (RA), axial spondyloarthritis (axSpA), psoriatic (PsA), systemic lupus erythematosus (SLE), sclerosis (SSc) and ANCA-associated vasculitis (AAV). Methods A cross-sectional sample of 16 421 from the National Database German Collaborative Arthritis Centers, aged <65 years were analysed. For each diagnosis, yearly rates absenteeism, employment...
Objective To investigate prevalence, incidence and medication of interstitial lung disease (ILD) among German individuals with rheumatoid arthritis (RA). Methods Nationwide BARMER claims data from 2007 to 2020 were used. RA-ILD was identified by diagnosis codes, prescription disease-modifying antirheumatic drugs (DMARDs) diagnostics. ILD assigned as incident or prevalent relative the year first diagnosis. We prescriptions glucocorticoids, conventional synthetic (cs), biological (b) targeted...
METARTHROS (Metabolic impact on joint and bone disease) is a nationwide German network to investigate the overlap between inflammatory metabolic diseases. The objective of this study was compare body mass index (BMI) distribution in patients with early established rheumatoid arthritis (RA) data from general population, evaluate association BMI patient characteristics clinical markers. examined collected at inclusion cohort CAPEA, biologics register RABBIT, National database Collaborative...
Pain and depressive symptoms are common in patients with rheumatoid arthritis (RA). Information on the prevalence treatment of both conditions German RA is scarce.Using data from a nationwide statutory health insurance fund (BARMER GEK), 6193 aged 18 to 79 years were provided questionnaire covering variety items such as demographics, medical condition quality life 2015. caused by joint disorder (11-point scale) was classified none existent/mild, moderate or severe. Depressive determined...
Musculoskeletal diseases and symptoms are very common in the general population. They lead to high healthcare costs pose a significant burden national economy.Based on data from population-based German National Cohort (GNC), frequencies of musculoskeletal reported, including back pain, osteoporosis, osteoarthritis, arthritis.Data were collected March 2014 2017 adults aged 20-75 years during first half baseline survey GNC. The sample comprised 101,779 interviewed subjects, 9370 subjects who...
Studies on prevalence rates of mental comorbidities in patients with juvenile idiopathic arthritis (JIA) have reported varying results and provided limited information related drugs. The purpose this study was to determine the selected health diagnoses range associated drug prescriptions among adolescents young adults (AYA) JIA compared general population controls.
To investigate the prevalence of diabetes in patients with RA and impact on self-reported outcomes health care. between ages 18 79 years were randomly selected from a nationwide statutory insurance fund surveyed about rheumatological care disease burden. Comorbid (E10–14) was analysed regarding age, sex, BMI socioeconomic status. Disease burden, comorbidity prescriptions compared without diabetes. Predictors identified by multivariate regression. Of 2535 patients, 498 (20%) had Diabetes more...
Objective. To investigate prevalence and patient-reported outcomes of dental implants in patients with Sjögren syndrome (SS). Methods. A total 205 female from an observational cohort study answered oral health questionnaires about periodontal signs symptoms, dentures, implants, comorbidities, therapies that may interfere bone remodeling. Data were compared the reports 87 healthy controls. Results. The older than controls (58 ± 12 54 14 yrs, respectively) differed substantially self-reported...