A5069761617- Viral Infectious Diseases and Gene Expression in Insects
- Protein purification and stability
- Microbial Metabolic Engineering and Bioproduction
- Plant biochemistry and biosynthesis
- Biosimilars and Bioanalytical Methods
- Antioxidant Activity and Oxidative Stress
- Advancements in Battery Materials
- Monoclonal and Polyclonal Antibodies Research
- Fungal and yeast genetics research
- Microbial Natural Products and Biosynthesis
- Fermentation and Sensory Analysis
- Biofuel production and bioconversion
- Bat Biology and Ecology Studies
- Primate Behavior and Ecology
- Supercapacitor Materials and Fabrication
- Optimal Experimental Design Methods
- CRISPR and Genetic Engineering
- Advanced Battery Materials and Technologies
- Wildlife Ecology and Conservation
Chaudhary Charan Singh Haryana Agricultural University
2023
Texas A&M University
2019-2021
Indian Institute of Technology Delhi
2015-2018
β-Caryophyllene is a plant terpenoid with therapeutic and biofuel properties. Production of terpenoids through microbial cells potentially sustainable alternative for production. Adaptive laboratory evolution complementary technique to metabolic engineering strain improvement, if the product-of-interest coupled growth. Here we use combination pathway adaptive improve production β-caryophyllene, an extracellular product, by leveraging antioxidant potential compound.Using oxidative stress as...
Achieving consistent product quality of a biotherapeutic is major target for any biopharmaceutical manufacturer, even more biosimilar producer as comparability with the innovator regulatory expectation. The complexity products and their tedious manufacturing processes, however, make this non‐trivial exercise. primary motivation work to develop an integrated chromatographic platform purification monoclonal antibody (mAb) therapeutics that can deliver desired separation both charge variants...
Biotherapeutics have become the focus of pharmaceutical industry due to their proven effectiveness in managing complex diseases. Downstream processes these molecules consist several orthogonal, high resolution unit operations designed so as be able separate variants having very similar physicochemical properties. Typical process development involves optimization individual based on Quality by Design principles order define design space within which can deliver product that meets predefined...
Development of a chromatographic step in time and resource efficient manner remains serious bottleneck protein purification. Chromatographic performance typically depends on raw material attributes, feed process factors, their interactions. Design experiments (DOE) based development is often chosen for this purpose. A challenge is, however, performing DOE with such large number factors. split approach knowledge order to reduce the proposed. The first targets optimizing factors that are...
With the rapid increase in use of lithium-ion batteries (LIBs), development safe LIBs has become an important social issue. Replacing flammable organic liquid electrolytes current with water can be alternative route to resolve this safety concern. The water-in-salt (WIS) received great attention as next-generation due their large electrochemical stability window. However, high cathodic limit remains a challenge, impeding low-potential anodes. Here, we report first biodirected synthesis...