Prostrate knotweed also called Polygonum aviculare is an important edible plant. The polygonum majorly known for the phenolics and antioxidants. antioxidants combat excessive free radicals within body. are implicated in various other diseases like diabetes, Alzheimer’s, inflammation. This study was aimed at exploring antioxidant bioactives their derivatizations to produce new molecules with advanced pharmacological features. We have isolated six compounds (1–6) from aviculare. Furthermore,...

Degradable implant membranes designed to separate hard and soft tissues trigger the growth of underlying bone with antimicrobial properties are needed for management defects, ridge augmentation facilitate dental implants. In this study, composite scaffolds poly(lactic acid) (PLA), poly(caprolactone) (PCL) blended nano hydroxyapatite cefixime‐β cyclodextrin (Cfx‐βCD) inclusion complexes were synthesized by electrospinning. The prepared electrospun fibrous characterized scanning electron...

Undoubtedly, in the new millennium, importance of energy sector for development a country is undeniable. Rapidly increasing knowledge along with speedy technological innovation has resulted provision abundance facilities. This made human beings, consumers or producers, much demanding sources that are used to run mechanical processes. There various which include oil, electricity, gas, coal and nuclear. Countries differ usage alternative sources. In Pakistan major source gas 41 percent total...

There is a need to develop pro-angiogenic biomaterials promote wound healing and assist in regenerative medicine. To this end, various growth factors have been exploited which the potential angiogenesis. However, these are generally expensive labile limits their effectiveness. An alternative approach immobilize heparin onto biocompatible degradable hydrogels. The turn will then bind endogenous proangiogenic induce formation of new blood vessels. In study, we continue our development...

Organocatalytic asymmetric Michael addition is a strong approach for C-C bond formation. The objective of the study to design molecules by exploiting efficiency Adducts. We proceeded with synthesis adducts tailoring substitution pattern on maleimide and trans-β-nitro styrene as acceptors. synthesized compounds were evaluated dual cyclooxygenases (COX) lipoxygenase (LOX) inhibition.The (4, 9-11) through additions. (COX-1 2) (5-LOX) assays used in vitro evaluations compounds. After acute...

Acute respiratory distress syndrome (ARDS), a serious manifestation of acute lung injury (ALI), is debilitating inflammatory disease that caused by multiple risk factors. One the primary causes can lead to ALI/ARDS cigarette smoke (CS) and its mode action via oxidative stress. Despite extensive research, no appropriate therapy currently available treat ALI/ARDS, which means there dire need for new potential approaches. In our study we explored protective effects 70 % methanolic-aqueous...

Electrochemical energy storage devices are ubiquitous for personal electronics, electric vehicles, smart grids, and future clean demand. SCs EES with excellent power density superior cycling ability. Herein, we focused on the fabrication DFT calculations of Na3-δ-MnO2 nanocomposite, which has layered MnO2 redox-active sites, supported carbon cloth. two-dimensional diffusion channels is not labile to structural changes during intercalation; therefore, it considered best substrate...

Differentiation of mouse trophoblast stem cells (TSCs) to giant (TGCs) has been widely used as a model system study placental development and function. While several differentially expressed genes, including regulators TSC differentiation, have identified, comprehensive analysis the global expression genes splice variants in two cell types not reported.Here, we report ~ 7800 TGCs compared TSCs which include cycle, apoptosis, cytoskeleton, mobility, embryo implantation, metabolism, various...

Inflammation, being a well-known and complex pathological condition, is always challenge to the human health. This research work was designed for rationale-based anti-inflammatory study on β-ketoester derivatives of N-ary succinimides. The compounds (A–D) were synthesized by organocatalytic Michael addition. initially screened in vitro 5-lipoxygenase (5-LOX) cyclooxygenase (COX-2) assays. For vivo activity, carrageenan-induced paw edema arachidonic acid-induced ear tests used. Furthermore,...

In the present study, cuttlefish bones are used to prepare highly porous hydroxyapatite (HA) scaffolds <italic>via</italic> hydrothermal treatment at 200 °C.

Alzheimer's disease (AD) is a neurodegenerative illness described predominantly by dementia. Even though has been known for over century, its origin remains mystery, and researchers are exploring many therapy options, including the cholinesterase technique. A decreased acetylcholine ACh neurotransmitter level believed to be among important factors in progression of disease.In continuation synthesizing potential anti-Alzheimer agents appreciative pharmacological amide-containing compounds,...

An oronasal fistula is a passage between the oral and nasal cavity. Currently, surgical procedures use mucosal flaps or collagen grafts to make barrier cavities. Our aim was develop cell-free synthetic repair material for closure of fistulas. We surface functionalized electrospun polyurethane (PU) poly-L-lactic acid (PLLA) composite polymer (PU-PLLA) membranes with acrylic through plasma polymerization. Membranes were treated in layer-by-layer approach highly charged electrostatic layer that...

In the current study, a ternary nanocomposite (NiO–ZnO–CaO) was successfully synthesized through co-precipitation method using Azadirachta Indica (neem) leaves extract as green approach. The characterization of prepared conducted FT-IR, XRD, SEM and EDS to determine metal oxides absorption bands, structural properties, elemental composition, surface morphology nanocomposite. FT-IR analysis revealed characteristic vibrational peaks at 621, 684, 721 cm −1 , corresponding Ni-O, Zn-O, Ca-O bond...

The utilization and subsequent deployment of resources characterize economicgrowth. A hallmark economic development is the after theirutilization. Due to scarcity energy sources unpredictability energypricing, it essential analyze past changes in value while developing an energystrategy. Energy plans must take into account ever-changing pricing thescarcity supplies by studying variations values throughout history.Renewable OECD nations examined this research, along with theeffects...

This research aims to identify the impact of ecological footprint, energy innovation and financial technology on climate change in G7 Countries. Ecological technology, resource management, development, industrialization, urbanization are significantly influencing Climate across World. Therefore, current study arranged panel dataset addressing evidence from economies. For this purpose, a Countries’ economies comprising 1990 2022 collected World development Indicators, IMF KOFG Index. First,...

The authority to carry out a job is matter of delegation power and jurisdiction. When women are empowered, they can make their own decisions have access resources. society strives for growth in its social economic spheres, it said be developing socially economically. Half the world's population comprises women, who comprise significant percentage via reproductive productive labor. This article examines significance women's empowerment socio-economic progress, which crucial country's...

The current study aims to use a facile and novel method remove Congo red (CR) Methyl Orange (MO) dyes from contaminated water with Maize offal biomass (MOB) its nanocomposite magnetic nanoparticles (MOB/MNPs). MOB MOB/MNPs were characterized Fourier-transform infrared (FTIR), scanning electron microscopy (SEM), BET, XRD point of zero charge (pHPZC). influence initial CR MO levels (20–320 mg/L), adsorbent dosage (1-3 g/L), pH (3-9), co-exiting ions, temperature (25–45 °C) time (15–180 min)...

With the rapid increase in use of lithium-ion batteries (LIBs), development safe LIBs has become an important social issue. Replacing flammable organic liquid electrolytes current with water can be alternative route to resolve this safety concern. The water-in-salt (WIS) received great attention as next-generation due their large electrochemical stability window. However, high cathodic limit remains a challenge, impeding low-potential anodes. Here, we report first biodirected synthesis...

Background: Ischemic heart disease (IHD) is one of the leading causes mortality in Pakistan. With advancement research, multiple have contributed development web causation this public health issue. The objective study was to assess gender differences risk factors associated with ischemic patients presenting at biggest cardiology hospital Lahore.&#x0D; Patients and methods: A comparative cross-sectional carried out Punjab Institute Cardiology, Lahore from January August, 2018 on a sample 296...