A5061650302- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Silk-based biomaterials and applications
- Periodontal Regeneration and Treatments
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Hydrogels: synthesis, properties, applications
- Diabetic Foot Ulcer Assessment and Management
- Proteoglycans and glycosaminoglycans research
- Angiogenesis and VEGF in Cancer
- Pressure Ulcer Prevention and Management
- Nanocomposite Films for Food Packaging
- biodegradable polymer synthesis and properties
- Dental materials and restorations
- Osteoarthritis Treatment and Mechanisms
- Graphene and Nanomaterials Applications
- Oral microbiology and periodontitis research
- Nanoparticles: synthesis and applications
- Nanoplatforms for cancer theranostics
- Dental Implant Techniques and Outcomes
- Electrochemical sensors and biosensors
- Natural Fiber Reinforced Composites
- Polymer Surface Interaction Studies
- Tissue Engineering and Regenerative Medicine
COMSATS University Islamabad
2015-2024
University of Lahore
2015-2021
Queen Mary University of London
2007
University College London
2007
Johnson Matthey (United Kingdom)
2007
Introduction: Diabetic wounds are challenging to treat due a wide range of pathophysiological changes. Hypoxia is one the predominant contributing factors poor vascularization and chronicity in diabetic wounds. This study was designed develop polycaprolactone (PCL)-based oxygen-releasing electrospun wound dressings evaluate their efficacy for improved full thickness healing rats. Methods: PCL-based oxygen releasing were made using electrospinning technology. The developed characterized terms...
A series of crystalline homometallic and heterometallic cobalt nickel hydroxides oxides were prepared using a continuous hydrothermal flow synthesis system. In all syntheses, the relevant metal salt solutions pumped under high pressure to meet pH or other chemical modifiers (H2O2 PVP) before mixture was brought into contact with feed superheated (or supercritical) water, whereupon precipitation particle growth occurred. The resulting nanoparticle (typically less than 100 nm in diameter)...
New blood vessel formation is an essential part of wound healing to provide cells with the nutrients and oxygen for their survival. Many nonhealing ulcers fail heal because poor supply skin grafts will also take on poorly vascularized beds. There a real need proangiogenic biomaterials assist healing. In vivo heparin binds growth factors helps regulate new formation, hence containing are attractive. To achieve hydrogel high binding capacity composite chitosan, poly(vinyl alcohol) (PVA)...
In this report, a gold nanoparticle decorated single walled carbon nanotube (SWCNTs) nanocomposite was shown to possess synergistic intrinsic peroxidase like activity and enhanced affinity towards H<sub>2</sub>O<sub>2</sub> oxidation.
This review summarizes current developments in improving the biological behavior of bioactive glasse and their composites.
There is a need to develop pro-angiogenic biomaterials promote wound healing and assist in regenerative medicine. To this end, various growth factors have been exploited which the potential angiogenesis. However, these are generally expensive labile limits their effectiveness. An alternative approach immobilize heparin onto biocompatible degradable hydrogels. The turn will then bind endogenous proangiogenic induce formation of new blood vessels. In study, we continue our development...
A novel eco-friendly high throughput continuous hydrothermal flow system was used to synthesise phase pure ZnO and doped in order explore their properties for tissue engineering applications. Cerium, zirconium, copper were introduced as dopants during synthesis of nanoparticles, Zirconium successfully synthesised, however secondary phases CeO CuO detected X-ray diffraction (XRD). The nanoparticles characterised using diffraction, Brunauer-Emmett-Teller (BET), Dynamic Light scattering...
In the maxillofacial area, specifically orbital floor, injuries can cause bone deformities in head and face that are difficult to repair or regenerate. Treatment methodologies include use of polymers, metal, ceramics on their own combinations mainly for purposes, but little attention has been paid identify suitable materials floor regeneration. Polyurethane (PU) hydroxyapatite (HA) micro- nano- sized with different percentages (25%, 40% & 60%) were used fabricate bioactive tissue engineering...
Following recent work from our group on a small ribose-derived sugar 2-deoxy-d-ribose which stimulates angiogenesis in chick chorionic allantoic membrane bioassay and skin wounds healthy rats, we tested the effect of this when added to common alginate wound dressing well-accepted diabetic model rats. Dressings were simply loaded with filter-sterilized solutions that proved stable at room temperature for least two weeks. Prior undertaking animal study, assessed vitro release dressings either...