A5084701879- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiomyopathy and Myosin Studies
- Cardiac electrophysiology and arrhythmias
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac tumors and thrombi
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Effects of Exercise
- Cardiovascular Disease and Adiposity
- Pericarditis and Cardiac Tamponade
- Venous Thromboembolism Diagnosis and Management
- Cardiac Ischemia and Reperfusion
- Ultrasound in Clinical Applications
- Aortic aneurysm repair treatments
- Pulmonary Hypertension Research and Treatments
- Advanced MRI Techniques and Applications
IRCCS Humanitas Research Hospital
2020-2024
Humanitas University
2020-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2022
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2003-2021
Vita-Salute San Raffaele University
2011-2021
IRCCS Ospedale San Raffaele
2004-2020
San Raffaele University of Rome
2010-2019
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2017
University of Messina
2017
Medical University of South Carolina
2016
Repair of mitral regurgitation (MR) is more demanding in case prolapse the anterior leaflet, posterior leaflet with calcified annulus, or both leaflets. We evaluated a repair which consists anchoring free edge prolapsing to corresponding facing leaflet: 'edge-to-edge' (E-to-E) technique. The correction results double orifice valve when middle portion and smaller close commissure.Out 432 patients MR submitted between January 1991 September 1997, 121 (mean age 56 +/- 15.8 years) underwent...
The introduction of devices for transcatheter aortic valve implantation, mitral repair, and closure prosthetic paravalvular leaks has led to a greatly expanded armamentarium catheter-based approaches patients with regurgitant as well stenotic valvular disease. Echocardiography plays an essential role in identifying suitable these interventions providing intra-procedural monitoring. Moreover, echocardiography is the primary modality post-procedure follow-up. echocardiographic assessment...
Valvular regurgitation represents an important cause of cardiovascular morbidity and mortality. Imaging is pivotal in the evaluation native valve echocardiography primary imaging modality for this purpose. The assessment valvular should integrate quantification regurgitation, anatomy function, consequences disease on cardiac chambers. In clinical practice, management patients with largely relies results imaging. It crucial to provide standards that aim at establishing a baseline list...
AimsThis study sought to evaluate the feasibility and early outcomes of a percutaneous edge-to-edge repair approach for mitral valve regurgitation with MitraClip® system (Evalve, Inc., Menlo Park, CA, USA).
Background— The aim of this study was to assess the results mitral valve (MV) repair in functional regurgitation because end-stage dilated cardiomyopathy (DCM). Methods and Results— Seventy-seven patients with idiopathic (26 patients) or ischemic (51 DCM underwent MV for (3 4+/4+). Fifty-eight (75.3%) were New York Heart Association class III, 19 (24.6%) IV. In 23 (29.8%) a coaptation depth <1 cm, an isolated undersized annuloplasty used. remaining 54 (70.1%), ≥1 “edge-to-edge” technique...
Arterial hypertension is frequently associated with the presence of structural alterations in small arteries. Moreover, a reduced coronary flow reserve and vasodilator capacity has been observed essential hypertensive patients, possibly due, at least part, to microangiopathy vessels. The aim present study was evaluate possible relationship between subcutaneous artery structure or patients hypertension.A total 20 mild moderate were included study, underwent biopsy fat from gluteal region....
AimsCardioband system is a direct annuloplasty adjustable device that implanted in the beating heart on posterior annulus under fluoroscopic and transoesophageal echocardiographic (TEE) guidance. We report early (1 month) outcomes of first-in-man pre-CE-mark feasibility safety trial.
With an increasing prevalence of patients with valvular heart disease (VHD), a dedicated management approach is needed. The challenges encountered are manifold and include appropriate diagnosis quantification valve lesion, organization adequate follow-up, making the right decisions, in particular regard to timing choice interventions. Data from Euro Heart Survey have shown substantial discrepancy between guidelines clinical practice field VHD many denied surgery despite having clear...
The Cardioband™ (Edwards Lifesciences) is a transcatheter implant designed to reduce mitral annulus size and regurgitation (MR) severity. We report the 1-year outcomes of consecutive patients who underwent Cardioband procedure between 2013 2016. Sixty with moderate or severe secondary MR (72 ± 7 years, 60% ischaemic origin) on guideline-recommended medical therapy were treated analyzed at 11 European institutions. There two in-hospital deaths (none device-related), one stroke, coronary...
The aim of this study was to report medium-term outcomes MitraClip implantation in inoperable or high-risk surgical candidates with functional mitral regurgitation (FMR) our single-centre experience. From October 2008, 109 consecutive patients FMR underwent (mean age 69±9 years; 82% NYHA Class III-IV). Logistic EuroSCORE 22±16%. Comorbidities included: chronic renal failure (47%), diabetes (22%), COPD (28%). Mean EF 28±11%; LVEDD 68±8 mm. Procedural success 99% and 30-day mortality 1.8%. At...
To assess the evolution of tricuspid regurgitation (TR) in dilated cardiomyopathy (DCM) patients submitted to mitral repair for functional (MR).Ninety-one DCM (mean age 61+/-11.3) MV (+/-tricuspid repair) MR were included. Preoperative EF was 30.9+/-6.5%, left ventricular (LV) end-diastolic volume 113+/-31.5 ml/m(2), LV end-systolic 81.8+/-26.7 > or =3+/4+. TR classified as < =1+/4+ 57 (62.6%), 2+/4+ 21 (23%) and =3+/4+ 13 (14.2%). Most NYHA class III IV. A annuloplasty associated whenever...